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CTAG2


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Symbol:CTAG2
Name(s):cancer/testis antigen 2
Type:protein-coding
Organism:Homo sapiens
Synonyms:CAMEL, ESO2, LAGE-1, LAGE-2b, MGC138724, MGC3803
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17899192 Observational study of gene-disease association. (HuGE Navigator)
14559844 Data support the immunogenicity of NY-ESO-1/LAGE-1 ORF2 gene products and clearly demonstrate their capability to stimulate T-helper 1 type CD4+ T cells.
14522938 Data showed aberrant expression of NY-ESO-1 and LAGE-1 by IHC/RT-PCR in a significant proportion of epithelial ovarian cancer patients.
15540228 first peptide epitope recognized by sera from a wide spectrum of cancer patients but not healthy donors
15067093 Isolation of CD4+ T cell clones from T cell cultures of two healthy donors leads to identification of four naturally processed HLA-DR-binding CAMEL epitopes, interesting peptides to investigate for future cancer immunotherapy.
12538712 CD4+ T cell clones specific for alternatively translated tumor antigen CAMEL have been isolated from the peripheral blood of a melanoma patient; CAMEL(81-102) is described as a naturally processed epitope recognized and presented by HLA-DR11 and HLA-DR12.
16446548 LAGE-1 expression was detected in esophageal cancer by cDNA RDA. LAGE-1 might have the potential to be a target antigen for anti-tumoral immunotherapy in esophageal cancers because of its tumor-specific expression similar to that of MAGE-A1.
15061963 LAGE-1 expression was more frequently found in squamous cell carcinoma than in adenocarcinoma.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
BINDHomo sapiens LAGE-1 genehistone cluster 4, H4HIST4H4 (H4) interacts with the LAGE-1 (CTAG2) promoter.-Pubmed

Patents:

Patents logo
US Patent No.Title
7611839 Methods for diagnosing RCC and other solid tumors
7371519 Methods and kits for indirect labeling of nucleic acids
6558908 Methods and kits for indirect labeling of nucleic acids
6235483 Methods and kits for indirect labeling of nucleic acids

CTAG2 results (if any) from reagent suppliers

Google CSE Logo
CTAG2 antibodies: Cancer > Tumor immunology > Tumor-associated ...
CTAG2 antibodies. ... CTAG2 antibodies. Code. Name. Applications (see key) & Reactivity (see key). Image Abreview Publication. ab57218 · CTAG2 antibody ...
http://www.abcam.com/index.html?t=231241&pt=1&c=4315&ei=&mu=...

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Abgent - Tag and Specific Antibodies
AP1047aNEW, 6×His Tag Antibody, WB, E. AP1015a, BTag Antibody, WB, E, N/A. AT1664aNEW, CTAG2 monoclonal antibody (M04), ELISA,S-ELISA,WB-Re, H ...
http://www.abgent.com/products/category/tag_specific...

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LAGE-1 siRNA (h) sc-60916
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, CTAG2, 30848, Xq28, NM_020994, ...
http://www.scbt.com/datasheet-60916-lage-1-sirna-h.html...

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Abgent - Cell and Function Antibodies
AT1664aNEW, CTAG2 monoclonal antibody (M04), ELISA,S-ELISA,WB-Re, H. AT1665aNEW, CTBP1 monoclonal antibody (M01), ELISA,IF,IHC-P,S-ELISA,WB-Ce,WB-Re, H ...
http://www.abgent.com/products/category/cell_function...

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NY-ESO-1/LAGE-1 (H-110) Antibody sc-28244
Humano, CTAG2, 30848, Xq28, NM_020994, NM_172377 · O75638 · 300396. Información sobre pedidos. Descripción del producto, Número de catálogo, Unidad, Precio ...
http://www.scbt.com/es/datasheet-28244-ny-eso-1-lage-1-h-110...

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Abcam antibodies and reagents product map
... CD22 proteins and peptides (1) · CD66a + CD66c + CD66d + CD66e antibodies (3 ) · CTAG2 antibodies (1) · CTAGE5 antibodies (1) · CTHRC1 antibodies (3) ...
http://www.abcam.com/index.html?pageconfig=productmap&cl=228...

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NY-ESO-1/LAGE-1 (H-110) Antibody sc-28244
Humain, CTAG2, 30848, Xq28, NM_020994, NM_172377 · O75638 · 300396. Produits disponibles. Nom du produit, Référence, Cond. Prix HT, Quantité, Favoris ...
http://www.scbt.com/fr/datasheet-28244-ny-eso-1-lage-1-h-110...

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