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HIF1A
| Symbol: | HIF1A | | Name(s): | hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18083891 |
mitochondrial abnormalities that disturb the reactive O(2) species HIF-1alpha-Kv1.5 O(2)-sensing pathway contribute to the pathogenesis of pulmonary arterial hypertension and cancer--REVIEW |
| 18163427 |
There was a significant correlation between nuclear BNIP3 expression and HIF-1alpha expression and HIF-2alpha expression but no correlation between BNIP3 and pre-operative PSA, tumor volume, margin positivity or capsular invasion. |
| 17984117 |
hypoxia-independent promotion of the AKT-HIF-1alpha-VEGF pathway contributes, at least in part, to gastric cancer tumorigenesis and angiogenesis |
| 18290322 |
A role for HIF1A as an endogenous marker of tumor hypoxia is currently not supported by the available clinical data. |
| 17828303 |
Transactivates SAG (sensitive to apoptosis gene) in response to hypoxia. |
| 17999410 |
differential expression of prolidase in 2 breast cancer cell lines showed prolidase-dependent differences in HIF-1 alpha levels |
| 18000826 |
HIF-1 alpha polymorphisms may have a significant influence on the poor prognosis of the patients undergoing radical cystectomy for bladder cancer, while they seem to have no relation to the bladder cancer occurrence |
| 18055454 |
HIF-1 and HIF-2 have roles in SK1 upregulation during hypoxia in glioma cells |
| 18279708 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18024476 |
CCAAT/enhancer-binding protein alpha antagonizes transcriptional activity of hypoxia-inducible factor 1 alpha with direct protein-protein interaction | →View more information from publications. |
Recent Publications on HIF1A: |  |
Hypoxia is Important for Establishing Vascularization During Corpus Luteum Formation in Cattle.
Hypoxia-inducible factor 1 (HIF1) has been demonstrated to have critical... | 3rd November, 2009
| Laboratory of Reproductive Endocrinology, Graduate School of Natural
| J Reprod Dev. 2009 Nov 2.
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[Angiogenic inhibitors and radiotherapy: from the concept to the clinical trial]
Increasing studies show the central role of the tumor microenvironment,... | 3rd November, 2009
| Departement des Radiations, Institut Claudius-Regaud, 31052 Toulouse,
| Cancer Radiother. 2009 Oct;13(6-7):562-7. Epub 2009 Aug 19.
DOI Direct Link |
Role for CaMKII inhibition in rheumatoid arthritis: effects on HIF-1-induced VEGF production by rheumatoid synovial fibroblasts.
BACKGROUND AND AIMS: The present study was designed to investigate the... | 30th October, 2009
| Department of Rheumatology and Clinical Immunology, University Medical
| Ann N Y Acad Sci. 2009 Sep;1173:706-11.
DOI Direct Link |
Possible neuroprotective effect of brimonidine in a mouse model of ischaemic optic neuropathy.
PURPOSE: To investigate the neuroprotective effect of brimonidine... | 29th October, 2009
| Pediatric Division of Ophthalmology, Schneider Children's Medical Center
| Clin Experiment Ophthalmol. 2009 Sep;37(7):718-29.
DOI Direct Link |
FLT3-ITD induces ara-C resistance in myeloid leukemic cells through the repression of the ENT1 expression.
Fms-related tyrosine kinase 3-internal tandem duplications (FLT3-ITD) are... | 27th October, 2009
| Department of Laboratory Medicine, Tokai University School of Medicine,
| Biochem Biophys Res Commun. 2009 Oct 22.
DOI Direct Link |
→View more research publications. |
HIF1A results (if any) from reagent suppliers | 
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HIF-1a Antibody
sists of two subunits, HIF-1a and HIF-1b belonging to the basic helix-loop-helix proteins of the ... endogenous levels of total HIF-1a protein. The antibody ...
http://www.cellsignal.com/pdf/3716.pdf...
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HIF1A Antibody
Specific antibody for the gene product of HIF-1A, the protein Hypoxia-inducible factor 1 alpha. Validated for specificity by gene-silencing with siRNA ...
http://www.piercenet.com/Products/Browse.cfm?fldID=0F6F0C02-...
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Monoclonal Anti-HIF-1a antibody produced in mouse (H6536) - Datasheet
Monclonal Anti-HIF-1α. Clone H1α67. Purified Mouse Immunoglobulin. Product Number H 6536. Product Description. Monoclonal Anti-HIF-1α (Hypoxia Inducible
...
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Datashee...
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HIF-1a Transcription Factor Assay Kit
Transcription Factor HIF-1a Specific Competitor dsDNA 1 vial ... Cayman's HIF1a Transcription Factor Assay is a non-radioactive, sensitive method for ...
http://www.caymanchem.com/pdfs/10006910.pdf...
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HPA001275 Anti-HIF1A antibody produced in rabbit Prestige ...
HPA001275 Anti-HIF1A antibody produced in rabbit Prestige Antibodies Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=HPA0...
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The Abcam catalog
Current highlights: All articles | This pathway card describes the process of cardiac lineage and includes some representative markers | Cardioprotective ...
http://www.abcam.com/index.html?t=61733&pt=1&c=333...
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HIF1A protein, Hif-1 alpha recombinant protein
Buy quality HIF1A protein (n/a), HIF1A, Hif-1 alpha recombinant protein, (n/an/a ). Hif-1 alpha (530-826 aa) Human, Recombinant, E Coli; HIF-1 alpha; ...
http://www.genwaybio.com/product_info.php?products_id=38080...
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