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UBE2K
| Symbol: | UBE2K | | Name(s): | ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast) | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | DKFZp564C1216, DKFZp686J24237, E2-25K, HIP2, HYPG, LIG | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 16868077 |
Results suggest that in permeabilized, US11-expressing cells polyubiquitination of the MHC class I heavy chain substrate can be catalyzed by E2-25K. |
| 17092742 |
E2-25K is involved in aggregate formation of expanded polyglutamine proteins and polyglutamine-induced cell death. |
Recent Publications on UBE2K: |  |
E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages.
An E3 ubiquitin ligase mediates the transfer of activated ubiquitin from... | 29th January, 2008
| Department of Biochemistry, University of Washington, Box 357350, Seattle,
| Nat Struct Mol Biol. 2007 Oct;14(10):941-8. Epub 2007 Sep 16.
DOI Direct Link |
Ubiquitin-conjugating enzyme E2-25K increases aggregate formation and cell death in polyglutamine diseases.
Polyglutamine diseases are characterized by neuronal intranuclear... | 17th March, 2007
| Graduate School Neurosciences Amsterdam, Netherlands Institute for
| Mol Cell Neurosci. 2007 Jan;34(1):10-9. Epub 2006 Nov 7.
DOI Direct Link |
E2-25K mediates US11-triggered retro-translocation of MHC class I heavy chains in a permeabilized cell system.
In cells expressing human cytomegalovirus US11 protein, newly synthesized... | 26th October, 2006
| Department of Cellular and Molecular Physiology, Pennsylvania State
| Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11589-94. Epub 2006 Jul 25.
DOI Direct Link |
SUMO modification of the ubiquitin-conjugating enzyme E2-25K.
Post-translational modification with small ubiquitin-related modifier... | 6th May, 2005
| University of Gottingen, Department of Biochemistry I, Humboldt Allee 23,
| Nat Struct Mol Biol. 2005 Mar;12(3):264-9. Epub 2005 Feb 20.
DOI Direct Link |
Alzheimer's disease meets the ubiquitin-proteasome system.
Ubiquitin-positive deposits are histopathologically found in patients with... | 26th March, 2005
| Department of Life Science, Gwangju Institute of Science and Technology,
| Trends Mol Med. 2004 Nov;10(11):565-70.
DOI Direct Link |
→View more research publications. |
UBE2K results (if any) from reagent suppliers | 
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HIP2 (A-15) Antibody sc-50733
Mouse, Ube2k, 53323, 5 C3.1, P61087, N/A. Ordering Information. Product Name, Catalog #, Unit, Price, Qty, Wish List. HIP2 (A-15), sc-50733, 200 µg/ml, $259
...
http://www.scbt.com/datasheet-50733-hip2-a-15-antibody.html...
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04604 Lin IBC Poster.indd
Ube2k ubiquitin-conjugating enzyme E2K. Cytoplasm. 2000. 9.57%. Pms2 postmeiotic segregation increased 2. Nucleus. 409. 12.76%. Actb beta-actin. Cytoplasm ...
http://www.sigmaaldrich.com/etc/medialib/safc/biosciences/bi...
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HIP2 siRNA (m) sc-41985
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Mouse, Ube2k, 53323, 5 C3.1, P61087 ...
http://www.scbt.com/datasheet-41985-hip2-sirna-m.html...
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New Products: Enzymes
UBE2K, Recombinant Human Ubiquitin-Conjugating Enzyme E2K. UBE2L3, Recombinant Human Ubiquitin-Conjugating Enzyme E2L 3 ...
http://www.atsbio.com/catalog/new-enzymes.html...
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Huntingtin-Interacting Protein Antibody / Huntingtin-Interacting ...
Huntingtin-Interacting Protein Antibody / Huntingtin-Interacting Protein Antibodies.
http://www.scbt.com/ko/table-huntingtin-interacting_protein....
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