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ANXA7


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Gene DB Home
Symbol:ANXA7
Name(s):annexin A7
Type:protein-coding
Organism:Homo sapiens
Synonyms:ANX7, SNX
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17708571 Decreased ANXA7 expression was mostly associated with high invasive potential in multiple tumors. The lymph node metastases from different sites (including prostate and breast) had decreased ANXA7 expression.
17018618 ANXA7 and p53 can distinctly regulate LOX transcription that is potentially relevant to the arachidonic acid -mediated cell growth control in tumor suppression.
11994295 the calcium-dependent membrane fusion activity of annexin 7 in vitro is further potentiated by the combined addition of guanine nucleotide and protein kinase C
12445460 The penta-EF-hand domain of ALG-2 interacts with the amino-terminal domain of annexin VII in a Ca2+-dependent manner.
17112522 Annexin VII was present in reticulocytes but was then lost as the cells matured. A different pattern was found in band 3-deficient samples: annexin VII was in fact present in both mature and immature red cell membranes.
11839755 synexin mediates galectin-3 translocation to the perinuclear mitochondrial membranes, where it regulates mitochondrial integrity critical for apoptosis regulation.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDANXA7S100 calcium binding protein A10--Pubmed
HPRDannexin VII isoform 2Calpactin I, light chain--Pubmed
HPRDannexin VII isoform 2sorcin isoform a--Pubmed
HPRDannexin VII isoform 2sorcin isoform a--Pubmed

Recent Publications on ANXA7:

Pubmed Logo
Monosomy of chromosome 10 associated with dysregulation of epidermal growth factor signaling in glioblastomas.
CONTEXT: Glioblastomas--uniformly fatal brain tumors--often have both...
25th July, 2009
Department of Neurological Surgery, Northwestern Brain Tumor Institute, JAMA. 2009 Jul 15;302(3):276-89.
DOI Direct Link
A network model of a cooperative genetic landscape in brain tumors.
CONTEXT: Gliomas, particularly glioblastomas, are among the deadliest of...
25th July, 2009
Department of Neurological Surgery, Northwestern Brain Tumor Institute and JAMA. 2009 Jul 15;302(3):261-75.
DOI Direct Link
Annexin-A7 protects normal prostate cells and induces distinct patterns of RB-associated cytotoxicity in androgen-sensitive and -resistant prostate cancer cells.
The tumor suppressor role of annexin-A7 (ANXA7) was previously...
18th July, 2009
Department of Anatomy, Physiology and Genetics, Institute for Molecular Int J Cancer. 2009 Dec 1;125(11):2528-39.
DOI Direct Link
Proteomic analysis of changes induced by nonylphenol in Sprague-Dawley rat Sertoli cells.
Nonylphenol (NP) is a common environmental contaminant that is known to...
8th July, 2009
Immunology and Reproductive Biology Laboratory, Medical School, Nanjing Chem Res Toxicol. 2009 Apr;22(4):668-75.
DOI Direct Link
Enhanced heterogeneity of myocardial conduction and severe cardiac electrical instability in annexin A7-deficient mice.
OBJECTIVES: Annexin A7 is involved in cardiomyocyte membrane organization...
30th August, 2008
Department of Medicine-Cardiology, University of Bonn, Germany. Cardiovasc Res. 2007 Nov 1;76(2):257-68. Epub 2007 Jul 6.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7608395 Systemic lupus erythematosus diagnostic assay
7426441 Methods for determining renal toxins
7415358 Molecular toxicology modeling
7251568 Methods and compositions for regulating bone and cartilage formation
7235358 Methods and compositions for diagnosing and monitoring transplant rejection

View more patents.

ANXA7 results (if any) from reagent suppliers

Google CSE Logo
Anti-ANXA7 Polyclonal Antibody
Polyclonal Antibody against ANXA7 for use in Western Blot.
http://www.bioreagents.com/products/productDetails/productDe...

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Antibodies to Calcium-Associated Proteins
purified immunoglobulin, mouse ... Anxa7(11750) human ... ANXA7(310) rat ... Anxa7(155423), bovine, rabbit, chicken, human, rat, mouse, canine ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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ANXA7 Recombinant Protein
RP-38904, Pierce ANXA7 Recombinant Protein, 10 µg, $400.87 ... The RP-38904 ANXA7 protein is a full length bacterially expressed recombinant protein. ...
http://www.bioreagents.com/products/productDetails/productDe...

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Annexin VII (A-1) Antibody sc-17815
Species, Nome del gene, Codice del gene, Locus cromosoma, Isoform (mRNA) Accession #, codice accesso proteina, Numero d' ordine. Human, ANXA7, 310, 10q22
.2 ...
http://www.scbt.com/it/datasheet-17815-annexin-vii-a-1-antib...

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Annexin VII (A-1) Antibody sc-17815
Species, 遺伝子名, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. ヒト, ANXA7, 310, 10q22.2, NM_001156, ...
http://www.scbt.com/ja/datasheet-17815-annexin-vii-a-1-antib...

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Annexin VII (A-1) Antibody sc-17815
Humano, ANXA7, 310, 10q22.2, NM_001156, NM_004034 · P20073 · 186360. camundongo, Anxa7, 11750, 14 A3, Q07076, N/A. Informacoes sobre ordens ...
http://www.scbt.com/pt/datasheet-17815-annexin-vii-a-1-antib...

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Annexin VII (G-8) Antibody sc-55488
Humano, ANXA7, 310, 10q22.2, NM_001156, NM_004034 · P20073 · 186360. Ratón, Anxa7, 11750, 14 A3, Q07076, No Aplicable ...
http://www.scbt.com/es/datasheet-55488-annexin-vii-g-8-antib...

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