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HLA-DRB1
| Symbol: | HLA-DRB1 | | Name(s): | major histocompatibility complex, class II, DR beta 1 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | DRB1, HLA DRB1, HLA-DR1B, HLA-DRB1* | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18275683 |
HLA-DRB1 alleles could act alone or in combination with other genes to confer differential susceptibility |
| 18256425 |
findings show presence of HLA-DRB1*04 was associated with severe malaria (OR = 2.42, 95% CI = 1.64, 3.58) in northern Gabon |
| 18069933 |
DRB1*0715 differs from DRB1*070101 in a point nucleotide mutation at codon 21 (ACG-->AAG), which produces an amino acid residue change from T to K. |
| 18086264 |
DRB1*1613N is a DRB1 null allele. |
| 18186801 |
In this study, samples from 95 SARS patients and 403 healthy controls were typed for HLA-A, -B and -DRB1 alleles and no association was found between HLA variations and SARS. |
| 17964196 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18203322 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18222012 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18223493 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18236804 |
Observational study of gene-disease association. (HuGE Navigator) | →View more information from publications. |
Interacting gene products |
| Interaction Type |
Gene 1 |
Gene 2 |
Interaction description |
Complex |
Publication Link |
| HPRD | major histocompatibility complex, class II, DR alpha precursor | major histocompatibility complex, class II, DR beta 1 precursor | - | - | Pubmed |
| HPRD | major histocompatibility complex, class II, DR alpha precursor | major histocompatibility complex, class II, DR beta 1 precursor | - | - | Pubmed |
| HPRD | major histocompatibility complex, class II, DR beta 1 precursor | TRA@ protein | - | - | Pubmed |
| HPRD | major histocompatibility complex, class II, DR beta 1 precursor | TRA@ protein | - | - | Pubmed |
Recent Publications on HLA-DRB1: |  |
HLA-DRB1*01 allele and low plasma IgG1 concentration may predispose to herpes-associated recurrent lymphocytic meningitis.
Recurrent lymphocytic meningitis (RLM) is a rare illness caused mostly by... | 3rd November, 2009
| Pain Clinic, Department of Anaesthesiology and Intensive Care Medicine,
| Hum Immunol. 2009 Oct 29.
DOI Direct Link |
Presence of CSF oligoclonal bands (OCB) is associated with the HLA-DRB1 genotype in a West Australian multiple sclerosis cohort.
High-resolution HLA-DRB1 genotyping was performed in 97 OCB-positive and... | 3rd November, 2009
| Australian Neuromuscular Research Institute, Sir Charles Gairdner
| J Neurol Sci. 2009 Oct 29.
DOI Direct Link |
Association of HLA-DRB1* and keloid disease in an Afro-Caribbean population.
Summary Background. Keloid disease (KD) is a fibroproliferative dermal... | 31st October, 2009
| Plastic and Reconstructive Surgery Research, Dermatological Sciences,
| Clin Exp Dermatol. 2009 Oct 23.
DOI Direct Link |
Genetic variants of CC chemokine genes in experimental autoimmune encephalomyelitis, multiple sclerosis and rheumatoid arthritis.
Multiple sclerosis (MS) is a complex disorder of the central nervous... | 30th October, 2009
| Neuroimmunology Unit, Department of Clinical Neuroscience, Center of
| Genes Immun. 2009 Oct 29.
DOI Direct Link |
Peptide microarray - based identification of Mycobacterium tuberculosis epitope binding to HLA-DRB1*0101, DRB1*1501 and DRB1*0401.
A more effective vaccine against Mycobacterium tuberculosis (Mtb) is... | 30th October, 2009
| Department of Microbiology, Tumor and Cell Biology (MTC), Karolinska
| Clin Vaccine Immunol. 2009 Oct 28.
DOI Direct Link |
→View more research publications. |
Press Releases on HLA-DRB1:
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| Trubion Pharmaceuticals, Inc. Announces Transition in Company Leadership |
16th November, 2009 |
Trubion Pharmaceuticals, Inc. |
SEATTLE, Nov. 16 /PRNewswire-FirstCall/ -- Trubion Pharmaceuticals, Inc. (Nasdaq: TRBN) announced today that Peter Thompson, M.D., FACP, President, Chief Executive Officer, Chairman of the
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| Trubion Announces Acceptance of Two Presentations on Its TRU-016 Product Candidate at the 2009 ASH Annual Meeting |
11th November, 2009 |
Trubion Pharmaceuticals, Inc. |
SEATTLE, Nov. 11 /PRNewswire-FirstCall/ -- Trubion Pharmaceuticals, Inc. (Nasdaq: TRBN) announced today the acceptance of two data presentations on its product candidate, TRU-016,
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| Reportlinker Adds Global Stem Cell and Advanced Technologies Market |
10th November, 2009 |
Reportlinker |
-- Stem Cell Applications (regenerative medicine - neurological disorders,
orthopedics, cancer, hematological disorders, myocardial infarction and
cardiovascular diseases,
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| Trubion Pharmaceuticals, Inc. Reports Third Quarter and Nine Months 2009 Financial Results |
5th November, 2009 |
Trubion Pharmaceuticals, Inc. |
-- In Sept. 2009, patient enrollment was completed in the second Phase 2b
study (2203) of TRU-015 for RA.
2009 Financial Guidance
The company has
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| Trubion Announces Dates for Third Quarter and Nine Months 2009 Earnings Conference Call |
29th October, 2009 |
Trubion Pharmaceuticals, Inc. |
SEATTLE, Oct. 29 /PRNewswire-FirstCall/ -- Trubion Pharmaceuticals, Inc. (Nasdaq: TRBN), today announced that it plans to issue earnings results for its third quarter and nine months ended
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HLA-DRB1 results (if any) from reagent suppliers | 
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