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HLA-E
| Symbol: | HLA-E | | Name(s): | major histocompatibility complex, class I, E | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | DKFZp686P19218, EA1.2, EA2.1, HLA-6.2, MHC, QA1 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18332182 |
crystal structure of CD94-NKG2A in complex with HLA-E bound to a peptide derived from the leader sequence of HLA-G |
| 11137220 |
Observational study of genotype prevalence. (HuGE Navigator) |
| 11270642 |
Observational study of gene-disease association. (HuGE Navigator) |
| 11774212 |
Observational study of genotype prevalence. (HuGE Navigator) |
| 12929994 |
Observational study of genotype prevalence. (HuGE Navigator) |
| 15496202 |
Observational study of gene-disease association. (HuGE Navigator) |
| 15631661 |
Observational study of genotype prevalence. (HuGE Navigator) |
| 16003246 |
Observational study of gene-disease association. (HuGE Navigator) |
| 16362895 |
Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) |
| 16573557 |
Observational study of gene-disease association. (HuGE Navigator) | →View more information from publications. |
Interacting gene products |
| Interaction Type |
Gene 1 |
Gene 2 |
Interaction description |
Complex |
Publication Link |
| HPRD | Beta 2 microglobulin | major histocompatibility complex, class I, E precursor | - | - | Pubmed |
| HPRD | beta-2-microglobulin precursor | HLA-E | - | - | Pubmed |
| HPRD | CD8 antigen alpha polypeptide isoform 1 precursor | major histocompatibility complex, class I, E precursor | - | - | Pubmed |
| HPRD | CD8 antigen alpha polypeptide isoform 1 precursor | major histocompatibility complex, class I, E precursor | - | - | Pubmed |
| HPRD | major histocompatibility complex, class I, E precursor | killer cell lectin-like receptor subfamily C, member 1 isoform NKG2-A | - | - | Pubmed |
| HPRD | major histocompatibility complex, class I, E precursor | killer cell lectin-like receptor subfamily C, member 1 isoform NKG2-A | - | - | Pubmed |
| HPRD | major histocompatibility complex, class I, E precursor | killer cell lectin-like receptor subfamily C, member 2 | - | - | Pubmed |
| HPRD | major histocompatibility complex, class I, E precursor | killer cell lectin-like receptor subfamily C, member 2 | - | - | Pubmed |
| HPRD | major histocompatibility complex, class I, E precursor | killer cell lectin-like receptor subfamily D, member 1 isoform 1 | - | - | Pubmed |
| HPRD | major histocompatibility complex, class I, E precursor | killer cell lectin-like receptor subfamily D, member 1 isoform 1 | - | - | Pubmed |
Recent Publications on HLA-E: |  |
HLA-E and HLA-E-bound peptides: recognition by subsets of NK and T cells.
In humans, major histocompatibility complex (MHC) class I molecules... | 29th October, 2009
| Dipartimento di Medicina Sperimentale and Centro di Eccellenza per le
| Curr Pharm Des. 2009;15(28):3336-44.
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HPLC and MS analysis for the identification and characterisation of peptides presented in the context of the non-classical human leukocytes antigen (HLA) class I molecule HLA-E.
In addition to a variety of other techniques used in T-cell epitope... | 29th October, 2009
| Department of Experimental Medicine, Biochemistry section c/o Center of
| Curr Pharm Des. 2009;15(28):3325-35.
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Minimal requirement for induction of natural cytotoxicity and intersection of activation signals by inhibitory receptors.
Natural killer (NK) cells provide innate control of infected and... | 29th October, 2009
| Laboratory of Immunogenetics, National Institute of Allergy and Infectious
| Blood. 2009 Sep 24;114(13):2657-66. Epub 2009 Jul 23.
DOI Direct Link |
A high-throughput Taqman(R) approach for the discrimination of HLA-E alleles.
Abstract An association between human leukocyte antigen (HLA) molecules... | 23rd October, 2009
| 1 Department of Medical Immunology, University Medical Centre Utrecht
| Tissue Antigens. 2009 Oct 21.
DOI Direct Link |
FTY720 and SEW2871 reverse the inhibitory effect of S1P on natural killer cell mediated lysis of K562 tumor cells and dendritic cells but not on cytokine release.
The aims of this study are to examine the effect of sphingosine... | 14th October, 2009
| Department of Physiology, Institute of Basic Medical Sciences, University
| Cancer Immunol Immunother. 2009 Oct 13.
DOI Direct Link |
→View more research publications. |
Press Releases on HLA-E:
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| Trubion Pharmaceuticals, Inc. Announces Transition in Company Leadership |
16th November, 2009 |
Trubion Pharmaceuticals, Inc. |
SEATTLE, Nov. 16 /PRNewswire-FirstCall/ -- Trubion Pharmaceuticals, Inc. (Nasdaq: TRBN) announced today that Peter Thompson, M.D., FACP, President, Chief Executive Officer, Chairman of the
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| Trubion Announces Acceptance of Two Presentations on Its TRU-016 Product Candidate at the 2009 ASH Annual Meeting |
11th November, 2009 |
Trubion Pharmaceuticals, Inc. |
SEATTLE, Nov. 11 /PRNewswire-FirstCall/ -- Trubion Pharmaceuticals, Inc. (Nasdaq: TRBN) announced today the acceptance of two data presentations on its product candidate, TRU-016,
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| Reportlinker Adds Global Stem Cell and Advanced Technologies Market |
10th November, 2009 |
Reportlinker |
-- Stem Cell Applications (regenerative medicine - neurological disorders,
orthopedics, cancer, hematological disorders, myocardial infarction and
cardiovascular diseases,
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| Trubion Pharmaceuticals, Inc. Reports Third Quarter and Nine Months 2009 Financial Results |
5th November, 2009 |
Trubion Pharmaceuticals, Inc. |
-- In Sept. 2009, patient enrollment was completed in the second Phase 2b
study (2203) of TRU-015 for RA.
2009 Financial Guidance
The company has
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| Trubion Announces Dates for Third Quarter and Nine Months 2009 Earnings Conference Call |
29th October, 2009 |
Trubion Pharmaceuticals, Inc. |
SEATTLE, Oct. 29 /PRNewswire-FirstCall/ -- Trubion Pharmaceuticals, Inc. (Nasdaq: TRBN), today announced that it plans to issue earnings results for its third quarter and nine months ended
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HLA-E results (if any) from reagent suppliers | 
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Search Bioportfolio and other Life Science Sites for HLA-E,
or search for HLA-E on BioPortfolio's antibody search engine.
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