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HMMR
| Symbol: | HMMR | | Name(s): | hyaluronan-mediated motility receptor (RHAMM) | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | CD168, IHABP, MGC119494, MGC119495, RHAMM | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18174258 |
Androgen receptor regulates CD168 expression and signaling in prostate cancer |
| 17872502 |
RHAMM is expressed in embryhonic stem cells (ESC) and has an important role in maintenance of ESC pluripotency and proliferation. |
| 17978170 |
RHAMM-R3 peptide vaccination induced both immunologic and clinical responses, and therefore RHAMM constitutes a promising target for further immunotherapeutic approaches |
| 17922014 |
Overexpression of HMMR is associated with breast cancer |
| 17157168 |
RHAMM/CD168 R3-peptide (ILSLELMKL)-specific T-cell responses in chronic myeloid leukemia [CML] patients were demonstrated; vaccination strategies inducing such RHAMM-R3-directed effector T cells might enhance specific immune responses against CML cells. |
| 17395888 |
These data suggest that high molecular form hyaluronan is broken down by reactive oxygen species to form low-molecular-weight fragments that signal via RHAMM and RON to stimulate beat frequency. |
| 11716065 |
Hyaluronate receptors mediate glioma cell migration and proliferation. The expression of the HA-receptors, CD44, and RHAMM, is virtually ubiquitous amongst glioma cell lines, and glioma tumor specimens. |
| 15809329 |
The overall results suggest that IHABP regulates the subcelluar localization of Bach1 in order to fine-tune transactivation of Bach1 target genes such as heme oxygenase-1. |
| 15705883 |
Augmentation of RHAMM expression within human cancers, including myeloma, can directly affect centrosomal structure and spindle integrity and potentially modulate apoptotic and cell cycle progression pathways. |
| 12712331 |
Increased RHAMM expression may enhance and improve the invasion and metastasis of endometrial carcinomas | →View more information from publications. |
Recent Publications on HMMR: |  |
Effect of PPAR{gamma} Inhibition on Pulmonary Endothelial Cell Gene Expression: Gene Profiling In Pulmonary Hypertension.
Peroxisome proliferator-activated receptor type gamma (PPARgamma) is a... | 15th October, 2009
| Medical College of Georgia.
| Physiol Genomics. 2009 Oct 13.
DOI Direct Link |
Acute lymphoblastic leukemia-derived dendritic cells express tumor associated antigens: PNPT1, PMPCB, RHAMM, BSG and ERCC1.
In all types of leukemia both in children and adults there is a need for... | 9th September, 2009
| Department of Pediatric Oncology and Hematology, Medical University of
| Neoplasma. 2009;56(5):428-34.
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Privately managed marine reserves as a mechanism for the conservation of coral reef ecosystems: a case study from Vietnam.
Coral reef ecosystems have been declining at an alarming rate during... | 30th May, 2009
| Marine Institute, University of Plymouth, Drake Circus, UK.
| Ambio. 2009 Mar;38(2):72-8.
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Hyaluronan-mediated motility receptor gene single nucleotide polymorphisms and risk of breast cancer.
A recent study used a network modeling strategy to generate a set of genes... | 28th January, 2009
| University of Cambridge Strangeways Research Laboratory, Worts Causeway,
| Cancer Epidemiol Biomarkers Prev. 2008 Dec;17(12):3618-20.
DOI Direct Link |
A putative role for RHAMM/HMMR as a negative marker of stem cell-containing population of human limbal epithelial cells.
The corneal epithelium is maintained by stem cells located at the... | 7th August, 2008
| North East Stem Cell Institute and, Institute of Human Genetics,
| Stem Cells. 2008 Jun;26(6):1609-19. Epub 2008 Mar 20.
DOI Direct Link |
→View more research publications. |
HMMR results (if any) from reagent suppliers | 
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RHAMM (E-19) Antibody sc-16170
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, HMMR, 3161, 5q34, NM_012484, ...
http://www.scbt.com/datasheet-16170-rhamm-e-19-antibody.html...
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Mouse CD & Other Cellular Antigens
CD168, RHAMM, Hmmr, 70-73kD, broad, hyaluronan-mediated motility receptor, adhesion, cell locomotion, tumor metastasis (intracellular in human breast
cancer ...
http://www.ebioscience.com/ebioscience/whatsnew/mousecdchart...
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RHAMM (H-90) Antibody sc-25488
Humano, HMMR, 3161, 5q34, NM_012484, NM_012485 · O75330 · 600936. Ratón, Hmmr, 15366, 11 A5, Q00547, No Aplicable. Información sobre pedidos ...
http://www.scbt.com/es/datasheet-25488-rhamm-h-90-antibody.h...
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www.ebioscience.com
RHAMM, Hmmr broad hyaluronan-mediated motility receptor, adhesion, cell locomotion, tumor metastasis (intracellular in human breast cancer) ...
http://www.ebioscience.com/ebioscience/whatsnew/pdf/MouseCD_...
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RHAMM (H-90) Antibody sc-25488
Humano, HMMR, 3161, 5q34, NM_012484, NM_012485 · O75330 · 600936. camundongo, Hmmr, 15366, 11 A5, Q00547, N/A. Informacoes sobre ordens ...
http://www.scbt.com/pt/datasheet-25488-rhamm-h-90-antibody.h...
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RHAMM (E-19) Antibody sc-16170
Humain, HMMR, 3161, 5q34, NM_012484, NM_012485 · O75330 · 600936. Souris, Hmmr, 15366, 11 A5, Q00547, Non disponible ...
http://www.scbt.com/fr/datasheet-16170-rhamm-e-19-antibody.h...
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