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HMOX1


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Symbol:HMOX1
Name(s):heme oxygenase (decycling) 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:HO-1, bK286B10
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18275848 HO-1 upregulation by SAM was causally related to a decrease in NADPH-mediated production of oxygen radicals. Our results demonstrate that the HO-1/ferritin-system is a novel target of the antioxidant compound S-adenosylmethionine.
18200441 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18201862 Observational study of gene-disease association. (HuGE Navigator)
18307065 Increased decidual and serum HMOX1 levels, together with altered decidual expression of some stress-related genes in cases, support the role of oxidative stress and excessive maternal inflammatory response in the pathogenesis of PE.
12377749 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
12566526 Observational study of gene-disease association. (HuGE Navigator)
12579334 Observational study of gene-disease association. (HuGE Navigator)
12736395 Observational study of genotype prevalence and gene-disease association. (HuGE Navigator)
12872043 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
14521259 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDHeme oxygenase 1nitric oxide synthase 1--Pubmed
HPRDheme oxygenase 1Nitric oxide synthase 1--Pubmed
HPRDheme oxygenase 1heme oxygenase 1--Pubmed

Recent Publications on HMOX1:

Pubmed Logo
Effect of dietary fat to produce non-alcoholic fatty liver in the rat.
BACKGROUND AND AIM: Non-alcoholic steatohepatitis (NASH) belongs to a...
3rd November, 2009
Physiology M311, School of Biomedical, Biomolecular and Chemical Sciences, J Gastroenterol Hepatol. 2009 Aug;24(8):1463-71.
DOI Direct Link
Foxo1 integrates insulin signaling with mitochondrial function in the liver.
Type 2 diabetes is a complex disease that is marked by the dysfunction of...
20th October, 2009
Howard Hughes Medical Institute, Division of Endocrinology, Children's Nat Med. 2009 Oct 18.
DOI Direct Link
Signaling pathways involved in phase II gene induction by alpha, beta-unsaturated aldehydes.
Phase II enzymes are induced primarily through the common electrophile...
20th October, 2009
School of Natural Science, University of California at Merced, Merced, CA Toxicol Ind Health. 2009 May-Jun;25(4-5):269-78.
DOI Direct Link
The topical antimicrobial zinc pyrithione is a heat shock response inducer that causes DNA damage and PARP-dependent energy crisis in human skin cells.
The differentiated epidermis of human skin serves as an essential barrier...
8th October, 2009
Department of Pharmacology and Toxicology, College of Pharmacy, Arizona Cell Stress Chaperones. 2009 Oct 7.
DOI Direct Link
Novel strategy to identify genetic risk factors for COPD severity: a genetic isolate.
Studies using genetic isolates with limited genetic variation may be...
3rd October, 2009
University Medical Center Groningen, University of Groningen, Groningen, Eur Respir J. 2009 Sep 24.
DOI Direct Link

View more research publications.

Clinical Trials:

Clinical Trials Logo
The Effects of Oral Curcumin on Heme Oxygenase-1 (HO-1) in Healthy Male Subjects

Patents:

Patents logo
US Patent No.Title
7612181 Dual variable domain immunoglobulin and uses thereof
6706867 DNA array sequence selection
6960439 Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles
6964850 Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles
7169758 Use of hepcidin as a regulator of iron homeostasis

View more patents.

HMOX1 results (if any) from reagent suppliers

Google CSE Logo
Human/Mouse HO-1/HMOX1 Affinity Purified Polyclonal Ab
Detection of HO-1/HMOX1 with AF3776. Lysates from human A549 and DU145, ... Heme Oxygenase 1 (HO-1), also known as HMOX1 and Heat Shock Protein ...
http://www.rndsystems.com/pdf/AF3776.pdf...

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Antibodies to Oxidative Stress Proteins
Hmox1(24451) human ... HMOX1(3162), rat, mouse, IHC (f), WB, pricing. H6915, Anti-Herp (C-terminal) antibody produced in rabbit, affinity isolated antibody
...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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Human Total HO-1/HMOX1 DuoSet IC ELISA
of sandwich ELISAs to measure human HO-1/HMOX1 in cell lysates. .... recombinant human HO-1/HMOX1 when reconstituted with 500 mL of IC Diluent #4. A ...
http://www.rndsystems.com/pdf/DYC3776.pdf...

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HJ-HO
WH0003162M1, Monoclonal Anti-HMOX1 antibody produced in mouse, 5C6 (monoclonal), purified immunoglobulin, human ... HMOX1(3162) ...
https://www.sigmaaldrich.com/etc/controller/controller-page....

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Heme Oxygenase 1 (C-18) Antibody sc-1796
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIMâ„¢ Number. Human, HMOX1, 3162, 22q12.3, NM_002133 ...
http://www.scbt.com/datasheet-1796-heme-oxygenase-1-c-18-ant...

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Human Apoptosis Antibody Array - R&D Systems
Cleaved Caspase-3, HO-1/HMOX1/HSP32, Phospho-p53 (S392). Catalase, HO-2/HMOX2, Phospho-Rad17 (S635). cIAP-1, HSP27, SMAC/Diablo. cIAP-2, HSP60, Survivin ...
http://www.rndsystems.com/product_detail_objectname_humanapo...

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Human/Mouse/Rat HO-2/HMOX2 Affinity Purified Polyclonal Ab
28 Jun 2006 ... (HO-2/HMOX2) and the inducible heme oxygenase-1 (HO-1/HMOX1). HO-1 expression is induced by heme and other non-heme compounds. Human ...
http://www.rndsystems.com/pdf/AF3170.pdf...

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