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HRAS


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Symbol:HRAS
Name(s):v-Ha-ras Harvey rat sarcoma viral oncogene homolog
Type:protein-coding
Organism:Homo sapiens
Synonyms:CTLO, HRAS1, K-ras, N-ras, RASH1, c-bas/has
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18039947 Four cases of Costello syndrome had an unusually severe phenotype, associated in three cases with two unusual mutations, c.35G>A, p.G12D in two cases and c.34G>T, p.G12C in the other.
18048363 H-Ras interacts with Spry2-binding partners, c-Cbl and CIN85, in a Spry2-dependent manner.
11097227 Observational study of gene-disease association. (HuGE Navigator)
11303621 Observational study of gene-disease association. (HuGE Navigator)
11487538 Meta-analysis of gene-disease association. (HuGE Navigator)
12115522 Observational study of gene-disease association. (HuGE Navigator)
12540507 Observational study of gene-disease association. (HuGE Navigator)
12838617 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
14688016 Observational study of gene-disease association. (HuGE Navigator)
14693748 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
BINDv-raf murine sarcoma 3611 viral oncogene homolog-ARAF (A-Raf) interacts with an unspecified isoform of HRAS (Ha-Ras).-Pubmed
HPRDBcl 2v-Ha-ras Harvey rat sarcoma viral oncogene homolog isoform 1--Pubmed
HPRDB-cell lymphoma protein 2 alpha isoformH-Ras--Pubmed
HPRDB-Rafv-Ha-ras Harvey rat sarcoma viral oncogene homolog isoform 1--Pubmed
HPRDv-raf murine sarcoma viral oncogene homolog B1H-Ras--Pubmed
HPRDCDC 25Av-Ha-ras Harvey rat sarcoma viral oncogene homolog isoform 1--Pubmed
HPRDcell division cycle 25AH-Ras--Pubmed
HPRDcell division cycle 25A isoform aH-Ras--Pubmed
HPRDgrowth factor receptor-bound protein 2 isoform 1v-Ha-ras Harvey rat sarcoma viral oncogene homolog isoform 1--Pubmed
HPRDgrowth factor receptor-bound protein 2 isoform 1v-Ha-ras Harvey rat sarcoma viral oncogene homolog isoform 1--Pubmed

Recent Publications on HRAS:

Pubmed Logo
Cytostatic Activity of Adenosine Triphosphate-Competitive Kinase Inhibitors in BRAF Mutant Thyroid Carcinoma Cells.
Context: The V600E mutation accounts for the vast majority of thyroid...
3rd November, 2009
Dipartimento di Biologia e Patologia Cellulare e Molecolare c/o Istituto J Clin Endocrinol Metab. 2009 Oct 30.
DOI Direct Link
Comprehensive Genomic Analysis Reveals Clinically Relevant Molecular Distinctions between Thymic Carcinomas and Thymomas.
PURPOSE: Thymomas and thymic carcinomas are rare intrathoracic...
29th October, 2009
Authors' Affiliations: Human Oncology and Pathogenesis Program (HOPP); Clin Cancer Res. 2009 Oct 27.
DOI Direct Link
Activating mutations in FGFR3 and HRAS reveal a shared genetic origin for congenital disorders and testicular tumors.
Genes mutated in congenital malformation syndromes are frequently...
27th October, 2009
Nat Genet. 2009 Nov;41(11):1247-52. Epub 2009 Oct 25.
DOI Direct Link
Viral DNA detection and RAS mutations in actinic keratosis and nonmelanoma skin cancers.
Summary Background Actinic keratosis (AK) is a well-established...
24th October, 2009
Laboratory of Clinical Virology, Medical School, University of Crete, Br J Dermatol. 2009 Aug 29.
DOI Direct Link
RAS Mutations Are the Predominant Molecular Alteration in Poorly Differentiated Thyroid Carcinomas and Bear Prognostic Impact.
Context: Poorly differentiated carcinomas represent an aggressive group of...
20th October, 2009
Department of Clinical and Biological Sciences (M.V., I.R., D.G., M.P.), J Clin Endocrinol Metab. 2009 Oct 16.
DOI Direct Link

View more research publications.

BioNews Results for HRAS

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BioPortfolio Logo
Profile: Erin Gainer
Pharmaceutical Executive:  Aug 18 2009 1:35PM Matching: hras

Patents:

Patents logo
US Patent No.Title
7231074 Method for determining the efficacy of an anti-cancer treatment using image analysis
7402579 Quinobenzoxazine analogs and compositions
7419808 Methods and compositions for the production of adenoviral vectors
7420100 Methods and compositions relating to HDAC 4 and 5 regulation of cardiac gene expression
7434729 Healthcare card closed loop network

View more patents.

HRAS results (if any) from reagent suppliers

Google CSE Logo
H-Ras Antibody / H-Ras Antibodies
H-Ras Antibody / H-Ras Antibodies. ... H-Ras specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-h-ras.html...

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HRAS Antibody
Specific antibody for the gene product of HRAS, the protein v-Ha-ras. Validated for specificity by gene-silencing with siRNA followed by Western blot ...
http://www.piercenet.com/Products/Browse.cfm?fldID=63C942E4-...

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H-Ras (F235) Antibody sc-29
See how others have used H-Ras (F235): sc-29 antibody and or H-Ras (F235) antibody ... Western blot analysis of human recombinant H-Ras fusion protein.
...
http://www.scbt.com/datasheet-29-h-ras-f235-antibody.html...

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HRAS-like Suppressor 2 Antibody HRASLS2
HRAS-like Suppressor 2 antibody was raised against a synthetic peptide of HRAS- like Suppressor 2.,
http://www.prosci-inc.com/shop/catalog1/HRAS-like-Suppressor...

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H-Ras (259) Antibody sc-35
See how others have used H-Ras (259): sc-35 antibody and or H-Ras (259) antibody ... H-Ras (259): sc-35. Western blot analysis of Ras p21 expression in KNRK ...
http://www.scbt.com/datasheet-35-h-ras-259-antibody.html...

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vH RAS antibody [H-Ras-03] - Activation site (ab64705) | Abcam
Mouse monoclonal [H-Ras-03] to vH RAS - Activation site. RAS proteins are signal -transducing, guanine nucleotide-binding proteins that appear to function as ...
http://www.abcam.com/vH-RAS-antibody-H-Ras-03-Activation-sit...

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H-Ras (M90) Antibody sc-53959
mouse monoclonal IgG1, 200µg/ml; raised against recombinant H-Ras protein ... H- Ras (M90): sc-53959. Western blot analysis of H-Ras expression in BJ (A) and ...
http://www.scbt.com/datasheet-53959-h-ras-m90-antibody.html...

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