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par-6
| Symbol: | par-6 | | Name(s): | par-6 | | Type: | protein-coding | | Organism: | Drosophila melanogaster | | Synonyms: | CG5884, DPar-6, DPar6, Dm-Par-6, DmPAR-6, DmPar6, PAR6, Par | | Links: |
Pubmed,
Entrez Gene,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17726059 |
In addition to regulating Par-6-aPKC localization, Cdc42 increases aPKC activity by relieving Par-6 inhibition. |
| 15475968 |
PDZ domain plasticity has a role in internal recognition in the Par-6-Pals1 complex |
| 12900452 |
Results suggest that the interaction of crumbs and Par-6 complexes is required for the organization and maintenance of apical membranes and adherens junctions of photoreceptors. |
| 12629552 |
The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl. |
| 15456726 |
The distributions of several transmembrane proteins required for migration were abnormal following Par-6 or Par-3/Bazooka downregulation, possibly accounting for the migration defects |
Interacting gene products |
| Interaction Type |
Gene 1 |
Gene 2 |
Interaction description |
Complex |
Publication Link |
| BIND | bazooka CG5055-PA, isoform A [Drosophila melanogaster]. | par-6 CG5884-PB, isoform B [Drosophila melanogaster]. | Par-6 interacts with Bazooka. | - | Pubmed |
| BIND | par-6 CG5884-PA, isoform A [Drosophila melanogaster]. | atypical protein kinase C CG10261-PA, isoform A [Drosophila melanogaster]. | aPKC interacts with Par-6. | - | Pubmed |
| BIND | par-6 CG5884-PB, isoform B [Drosophila melanogaster]. | atypical protein kinase C CG10261-PA, isoform A [Drosophila melanogaster]. | Par-6 interacts with aPKC. | - | Pubmed |
| BIND | par-6 CG5884-PB, isoform B [Drosophila melanogaster]. | lethal giant larvae CG2671-PA, isoform A [Drosophila melanogaster]. | Par-6 interacts with Lgl. | - | Pubmed |
| BIND | par-6 CG5884-PB, isoform B [Drosophila melanogaster]. | Cdc42 CG12530-PB, isoform B [Drosophila melanogaster]. | Par-6 interacts with Cdc42. | - | Pubmed |
| BIND | par-6 CG5884-PB, isoform B [Drosophila melanogaster]. | Patj CG12021-PB, isoform B [Drosophila melanogaster]. | Par-6 interacts with Patj. | - | Pubmed |
Press Releases on par-6:
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| Omeros Corporation Reports Third Quarter 2009 Financial Results and Development Highlights |
19th November, 2009 |
Omeros Corporation |
-- Priced the Company's IPO on October 7, 2009, receiving net proceeds of
approximately $61.8 million, and began trading on The NASDAQ Global
Market under the ticker
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| Shamir Optical Industry Ltd. Reports Third Quarter 2009 Results |
18th November, 2009 |
Shamir Optical Industries Ltd. |
KIBBUTZ SHAMIR, Israel, Nov. 18 /PRNewswire-FirstCall/ -- Shamir Optical Industry Ltd. (Nasdaq: SHMR) ("Shamir"), a leading provider of innovative products and
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| Jiangbo Pharmaceuticals Announces First Quarter Fiscal Year 2010 Results |
17th November, 2009 |
Jiangbo Pharmaceuticals, Inc. |
LAIYANG, China, Nov. 17 /PRNewswire-Asia-FirstCall/ -- Jiangbo
Pharmaceuticals, Inc. (OTC Bulletin Board: JGBO) ("Jiangbo" or the "Company"),
a pharmaceutical company with
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| Patient Safety Technologies Reports Third Quarter Results |
17th November, 2009 |
Patient Safety Technologies, Inc. |
TEMECULA, Calif., Nov. 17 /PRNewswire-FirstCall/ -- Patient Safety Technologies, Inc. (OTC Bulletin Board: PSTX) today announced third quarter 2009 results.
"We are
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| Neuralstem, Inc. Reports Third Quarter Financial Results and Provides Business Update |
17th November, 2009 |
Neuralstem, Inc. |
ROCKVILLE, Md., Nov. 17 /PRNewswire-FirstCall/ -- Neuralstem, Inc. (NYSE Amex: CUR) today provided a financial and business update for the third quarter ended September 30, 2009.
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par-6 results (if any) from reagent suppliers | 
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PAR6 antibody (ab6022) | Abcam
Goat polyclonal to PAR6. PAR6 is a cell membrane protein involved in cell polarization and asymmetrical cell division processes as part of a multi protein
...
http://www.abcam.com/PAR6-antibody-ab6022.html...
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Anti-Par6beta (B8062) - Data Sheet
Par6, Par3, and atypical PKC (aPKC),1 that functions in different cell polarization events in a ... (designated in humans Par6 α, β, and γ). All three
Par6 ...
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Datashee...
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PAR6 antibodies: Cancer > Cell cycle > Cell division | Abcam
PAR6 antibodies. ... PAR6 antibody - Aminoterminal end. WB. Rabbit polyclonal. ab53228 · PAR6 antibody - Carboxyterminal end. WB. Rabbit polyclonal ...
http://www.abcam.com/index.html?t=50436&pt=1&c=4198&ei=&mu=r...
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PAR-2 (N-19) Antibody sc-8206
PAR-2 activation regulates IL-8 and GRO-alpha synthesis by NF-kappaB, but not RANTES, IL-6, eotaxin or TARC expression in nasal epithelium. ...
http://www.scbt.com/datasheet-8206-par-2-n-19-antibody.html...
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PAR6 proteins and peptides: Stem Cells > Cancer Stem Cells ...
PAR6 proteins and peptides. ... Applications (see key) & Reactivity (see key). Image Abreview Publication. ab49775 · PAR6 peptide ...
http://www.abcam.com/index.html?t=50436&pt=2&c=4585&ei=&mu=r...
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Phospho-PAR-4 (Thr163) Antibody
studies PAR-4 was found in the yeast two-hybrid system .... 6. Incubate membrane with HRP-conjugated secondary antibody (1:2000) and ...
http://www.cellsignal.com/pdf/2329.pdf...
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Anti-Par6alpha (C-terminal) (C2484) - Data Sheet
Par6, Par3 and atypical PKC (aPKC),1 that functions in different cell polarization events in a wide ... carboxy-terminal side of the CRIB motif, Par6
has a ...
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Datashee...
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