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BIRC3
| Symbol: | BIRC3 | | Name(s): | baculoviral IAP repeat-containing 3 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18216531 |
The sequencing analysis of RT-PCR prducts confirmed the presence of the characteristic API2-MALT1 fusion transcript in patients with MALT lymphoma. |
| 17927572 |
Levels of IAP-2 and Bax were decreased in A375 cells and HIF-1alpha was increased during hypoxia. |
| 17626072 |
Bortezomib inhibited expression of cIAP-1, cIAP-2, and XIAP, which are regulated by NF-kappaB and function as inhibitors of apoptosis. |
| 12651874 |
cIAP1 and cIAP2 are potential oncogenes and are overexpressed in multiple lung cancers with or without higher copy numbers |
| 14562112 |
copy numbers of API2-MALT1 do not reflect tumor cell proportions, and that the number of copies of API2-MALT1 in a tumor cell is different for each clinical sample. |
| 16142363 |
IAP-2, XIAP, and survivin may make an important contribution to the resistance to the apoptotic effect of cisplatin in prostate cancer |
| 14527959 |
overexpression of PKC delta induced cIAP-2 promoter activity and increased NF-kappa B transactivation, suggesting regulation of cIAP-2 expression by a PKC delta/NF-kappa B pathway |
| 15982633 |
Taken together, our results strongly indicated that API2-MALT1 possesses a novel mechanism of self-activation by up-regulating its own expression in t(11;18)(q21;q21)-carrying MALT lymphomas. |
| 16984419 |
Persistent infection of epithelial cell line with Chlamydophila pneumoniae resulted in the upregulation of the NF-kappaB regulated inhibitor of apoptosis protein 2 but not inhibitor of apoptosis protein 1 and apoptosis resistance. |
| 14960576 |
levels of c-IAP1 and c-IAP2 are regulated by Smac/DIABLO through the ubiquitin/proteasome pathway | →View more information from publications. |
Recent Publications on BIRC3: |  |
Age-associated changes in cardiac gene expression after preconditioning.
BACKGROUND: Cardiac protection afforded by ischemic preconditioning (IPC)... | 28th October, 2009
| Department of Anesthesiology, Stony Brook University School of Medicine,
| Anesthesiology. 2009 Nov;111(5):1052-64.
DOI Direct Link |
Fas activation increases neural progenitor cell survival.
Although there is a sizable amount of research focusing on adult neural... | 16th October, 2009
| Neuroscience Graduate Program, University of Vermont, Burlington, Vermont.
| J Neurosci Res. 2009 Oct 14.
DOI Direct Link |
Cytotoxic effect of recombinant Mycobacterium tuberculosis CFP-10/ESAT-6 protein on the crucial pathways of WI-38 cells.
To unravel the cytotoxic effect of the recombinant CFP-10/ESAT-6 protein... | 15th September, 2009
| Institute of Biomedical Engineering, National Taiwan University, 1,
| J Biomed Biotechnol. 2009;2009:917084. Epub 2009 Jun 23.
DOI Direct Link |
Effects of cIAP-1, cIAP-2 and XIAP triple knockdown on prostate cancer cell susceptibility to apoptosis, cell survival and proliferation.
BACKGROUND: Manipulating apoptotic resistance represents an important... | 15th September, 2009
| UCD School of Medicine and Medical Science, University College Dublin,
| Mol Cancer. 2009 Jun 23;8:39.
DOI Direct Link |
Chronic crude garlic-feeding modified adult male rat testicular markers: mechanisms of action.
BACKGROUND: Garlic or Allium sativum (As) shows therapeutic effects such... | 12th September, 2009
| Unite de recherche n 01/UR/08-07, Faculte de Medecine, Tunis, Tunisie.
| Reprod Biol Endocrinol. 2009 Jun 24;7:65.
DOI Direct Link |
→View more research publications. |
BIRC3 results (if any) from reagent suppliers | 
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cIAP2 antibody (ab9705) | Abcam
Moreover, BIRC3 has several consensus glycosylation sites. Glycosylation can affect migration of proteins on SDS-PAGE [Hames, B.D and Rickwood, D., eds. ...
http://www.abcam.com/cIAP2-antibody-ab9705.html...
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c-IAP2 (H-85) Antibody sc-7944
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, BIRC3, 330, 11q22.2, NM_001165, ...
http://www.scbt.com/datasheet-7944-c-iap2-h-85-antibody.html...
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human MALT1 antibody, Affinity Purified conjugate
These translocations lead to fusions of API2(BIRC3)–MALT1 and IGH–MALT1 respectively. An additional translocation between MALT1 and MAP4 has also been
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http://www.ebioscience.com/ebioscience/specs/antibody_14/14-...
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Abgent - Apoptosis Antibodies
AP7694b, c ABL (ABL1) Antibody (C-term), WB, IHC, E, H. AP6124a, cIAP2 (BIRC3) Antibody (N-term), IHC, E, H. AP1307dNEW, mouse BID Antibody (S61), WB, E, M ...
http://www.abgent.com/products/category/apoptosis...
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TNFRSF1B antibody, TNF-RECEPTOR II (p75/p80) Antibody, Rat IgG2a ...
The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of ...
http://www.genwaybio.com/product_info.php?products_id=175021...
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Polyclonal Antibody to cIAP2
cIAP2 (API2, BIRC3, HIAP2, MIHC) is a member of the family of inhibitor of apoptosis proteins (IAP). IAPs suppress mitochondria-dependent and -independent
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http://www.imgenex.com/tds/IMG-5718.pdf...
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Panorama® Antibody Array - Signal Transduction
BIRC3. baculoviral IAP repeat-containing protein 3. 330 · BIRC5. baculoviral IAP repeat-containing 5 (survivin). 332 · BLK. B lymphoid tyrosine kinase ...
http://www.sigmaaldrich.com/life-science/cell-biology/protei...
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