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HSPB1
| Symbol: | HSPB1 | | Name(s): | heat shock 27kDa protein 1 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | CMT2F, DKFZp586P1322, HMN2B, HS.76067, HSP27, HSP28, Hsp25 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17928890 |
P38MAP kinase and HSP27 are phosphorylated in pemphigus skin |
| 16087758 |
Observational study of genotype prevalence. (HuGE Navigator) |
| 16215937 |
Observational study of genotype prevalence. (HuGE Navigator) |
| 17916631 |
A novel pathway regulating human myometrial contraction at labor with HSP27 and alphaB-crystallin as potential targets for future tocolytic studies. |
| 18031542 |
In response to UBV irradiation, HSP27 in melanocytes translocated from the cytoplasm to the nucleus. The HSP27 responses may provide some protective role against UVB-induced cell damage in the skin. |
| 17949744 |
Alterations in HSP27 may give early evidence for intracellular differences in aortic aneurysm of patients with bicuspid aortic valve and tricuspid aortic valve. |
| 18167217 |
Hsp27 inhibits oxidative stress-induced H9c2 damage and inhibition of ROS generation and the augmentation of Akt activation may be involved in the protective signaling. |
| 18089808 |
Hsp27 may play a general role in regulation of cellular senescence by modulating the p53 pathway. |
| 17974989 |
These data identify novel nongenomic mechanisms involving androgen, AR, and Hsp27 activation that cooperatively interact to regulate the genomic activity of AR. |
| 17823891 |
HSP-27 has the potential to redirect monocyte differentiation, derange dendritic cells (DC) and/or macrophage (Mphi)activation, and distort DC or Mphi interaction potential by altering receptor expression, signal transduction, or cytokine production. | →View more information from publications. |
Recent Publications on HSPB1: |  |
Comparative proteomic analysis of colon cancer cells in response to oxaliplatin treatment.
Colon cancer is one of the most common malignancies in the world.... | 31st October, 2009
| College of Life Science, Zhejiang Sci-Tech University, Hangzhou 310018,
| Biochim Biophys Acta. 2009 Oct;1794(10):1433-40. Epub 2009 Jun 8.
DOI Direct Link |
Human heat shock protein 27-overexpressing mice are protected against acute kidney injury after hepatic ischemia and reperfusion.
Liver ischemia-reperfusion injury (IRI) causes acute kidney injury (AKI)... | 29th October, 2009
| Dept. of Anesthesiology, Anesthesiology Research Laboratories, Columbia
| Am J Physiol Renal Physiol. 2009 Oct;297(4):F885-94. Epub 2009 Aug 5.
DOI Direct Link |
The pivotal role of the beta7 strand in the intersubunit contacts of different human small heat shock proteins.
Human alphaB-crystallin and small heat shock proteins HspB6 and HspB8 were... | 27th October, 2009
| Department of Biochemistry, School of Biology, Moscow State University,
| Cell Stress Chaperones. 2009 Oct 24.
DOI Direct Link |
Heat shock protein 27 phosphorylation: kinases, phosphatases, functions and pathology.
The small heat shock protein Hsp27 or its murine homologue Hsp25 acts as... | 23rd October, 2009
| Department of Microbiology and Virology, Faculty of Medicine, University
| Cell Mol Life Sci. 2009 Oct;66(20):3289-307. Epub 2009 Jul 11.
DOI Direct Link |
Transglutaminase-mediated intramolecular cross-linking of membrane-bound alpha-synuclein promotes amyloid formation in Lewy bodies.
The alpha-synuclein immunopositive and chaotrope-insoluble material from... | 22nd October, 2009
| Department of Psychiatry, Signaling and Apoptosis Research Group,
| J Biol Chem. 2009 Oct 2;284(40):27252-64. Epub 2009 Aug 3.
DOI Direct Link |
→View more research publications. |
HSPB1 results (if any) from reagent suppliers | 
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HSP27 (HSPB1) Antibody (S78)
HSP27 (HSPB1) Antibody (S78) Apoptosis, HSP27 (HSPB1) Antibody (S78) Cell Function, HSP27 (HSPB1) Antibody (S78) Protein Modification, HSP27 (HSPB1) ...
http://www.abgent.com/products/catalog_no/AP7199c...
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Hspb1 protein, Hsp27 recombinant protein
Buy quality Hspb1 protein (n/a), Hspb1, Hsp27 recombinant protein, (n/an/a). Hsp27, Human, Recombinant, E Coli; HspB1; Heat shock 27 kDa protein; HSP 27; ...
http://www.genwaybio.com/product_info.php?products_id=38024...
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HSP27 (HSPB1) Antibody (S15)
HSP27 (HSPB1) Antibody (S15) Apoptosis, HSP27 (HSPB1) Antibody (S15) Cell Function, HSP27 (HSPB1) Antibody (S15) Protein Modification, HSP27 (HSPB1) ...
http://www.abgent.com/products/catalog_no/AP7199b...
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Antibodies to Chaperonins and Heat Shock Proteins
Hspb1(24471), guinea pig, mouse, frog, rabbit, chicken, bovine, rat, human, ... Hspb1(15507), human, rat, turkey, rabbit, mouse, guinea pig, chicken, frog ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
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p-HSP 27 (Ser 15) Antibody sc-101699
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, HSPB1, 3315, 7q11.23, NM_001540 ...
http://www.scbt.com/datasheet-101699-p-hsp-27-ser-15-antibod...
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P1498 Anti-Heat Shock Protein 27 antibody produced in rabbit Anti ...
microarray: suitable. Gene Information, human ... HSPB1(3315). rat ... Hspb1( 24471). mouse ... Hspb1(15507). shipped in, dry ice. storage temp. −20°C ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=P149...
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Abgent - Apoptosis Antibodies
AP7199b, HSP27 (HSPB1) Antibody (S15), WB, IHC, E, H. AP7199c, HSP27 (HSPB1) Antibody (S78), WB, IHC, E, H. AP7199a, HSP27 (HSPB1) Antibody (S83), WB, E, H
...
http://www.abgent.com/products/category/apoptosis...
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