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HSP90AA1
| Symbol: | HSP90AA1 | | Name(s): | heat shock protein 90kDa alpha (cytosolic), class A member 1 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | FLJ31884, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18229454 |
A side-by-side comparison of the Hsp90-dependent chaperoning of Chk1 to that of the progesterone receptor (PR) was performed to show that these distinct types of clients have different chaperoning requirements. |
| 18211808 |
Overall, these results indicate that HDAC6 and HDAC10 play important roles in Hsp-mediated VEGFR regulation. |
| 18037622 |
HSP90 expression was significantly higher in tumors than nevi and was associated with disease progression |
| 17977914 |
exercise-heat acclimation resulted in increased baseline levels of HSP72 and HSP90; ex vivo heat inducibility of HSP72 was blunted after heat acclimation |
| 17427945 |
Stat1 in complex with Stat3 and HSF1 bound at the GAS element led to a moderate heat shock induction, designated as an "intrinsic" induction of the hsp90alpha gene; a changed level of heat shock induction was also controlled by the Stat1 on hsp90alpha. |
| 17908693 |
Hsp90 dimerization is required for in vivo function |
| 17975158 |
Blocking Hsp90 disrupts IGF-I and IL-6-induced proangiogenic signaling cascades by targeting IGF-IR and STAT3 in pancreatic cancer |
| 17956728 |
Hsp90-directed chaperones are regulators of mitochondrial integrity, and their organelle-specific antagonists may provide a previously undescribed class of potent anticancer agents. |
| 17707089 |
the staurosporine-induced death pathway bifurcates in caspase-compromised cells and commitment to apoptotic or necrotic phenotypes depends on cathepsin protease or Hsp90 chaperon activities. |
| 17978573 |
HSP90 stabilizes c-Jun protein, and so increases the total activity of c-Jun in HEK293 cells. | →View more information from publications. |
Recent Publications on HSP90AA1: |  |
Polymorphisms in the HSP90AA1 5' flanking region are associated with scrapie incubation period in sheep.
Susceptibility to scrapie is mainly controlled by point mutations at the... | 20th October, 2009
| Dpto. de Mejora Genetica Animal, INIA, 28040, Madrid, Spain.
| Cell Stress Chaperones. 2009 Oct 18.
DOI Direct Link |
Stress response genes are suppressed in mouse preimplantation embryos by granulocyte-macrophage colony-stimulating factor (GM-CSF).
BACKGROUND Granulocyte-macrophage colony-stimulating factor (GM-CSF) is... | 10th September, 2009
| Research Centre for Reproductive Health, Discipline of Obstetrics and
| Hum Reprod. 2009 Sep 8.
DOI Direct Link |
Freezability prediction of boar ejaculates assessed by functional sperm parameters and sperm proteins.
The objective of this work was to look for useful predictive indicators of... | 5th August, 2009
| Biotechnology of Animal and Human Reproduction (TechnoSperm), Department
| Theriogenology. 2009 Oct 15;72(7):930-48. Epub 2009 Aug 3.
DOI Direct Link |
Identification of novel hub genes associated with liver metastasis of gastric cancer.
Understanding hub genes involved in gastric cancer (GC) metastasis could... | 2nd July, 2009
| Department of Epidemiology, Second Military Medical University, and
| Int J Cancer. 2009 Dec 15;125(12):2844-53.
DOI Direct Link |
A SNP in the HSP90AA1 gene 5' flanking region is associated with the adaptation to differential thermal conditions in the ovine species.
Molecular chaperones have long been understood to be preferentially... | 6th June, 2009
| Departamento de Mejora Genetica Animal, INIA, Ctra. De La Coruna km 7,5,
| Cell Stress Chaperones. 2009 Jun 4.
DOI Direct Link |
→View more research publications. |
HSP90AA1 results (if any) from reagent suppliers | 
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HSP90AA1 protein, HSP 90 recombinant protein
Buy quality HSP90AA1 protein (n/a), HSP90AA1, HSP 90 recombinant protein, (n/an/ a). HSP 90 (1-732aa), Human, Recombinant, His-tag, E Coli; HSP 86; ...
http://www.genwaybio.com/product_info.php?products_id=38022...
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HSP 90α/β (H-114) Antibody sc-7947
... Protein Accession #, OMIM™ Number. Human, HSP90AA1, 3320, 14q32.31, NM_001017963, NM_005348 · P07900 ... Mouse, Hsp90aa1, 15519, 12 F1, P07901 ...
http://www.scbt.com/datasheet-7947-hsp-90alpha-beta-h-114-an...
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HSP90AA1 protein, HSP90 Alpha Human recombinant protein
Buy quality HSP90AA1 protein (e. coli), HSP90AA1, HSP90 Alpha Human recombinant protein, (n/an/a). HSPN, LAP2, HSP86, HSPC1, HSPCA, Hsp89, Hsp90, HSP90A, ...
http://www.genwaybio.com/product_info.php?products_id=45497...
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HSP 90α/β (F-8) Antibody sc-13119
Human, HSP90AA1, 3320, 14q32.31, NM_001017963, NM_005348 · P07900 · 140571. Mouse, Hsp90aa1, 15519, 12 F1, P07901, N/A. Ordering Information ...
http://www.scbt.com/datasheet-13119-hsp-90alpha-beta-f-8-ant...
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Antibodies to Chaperonins and Heat Shock Proteins
mouse ... Hsp90aa1(15519), Hsp90ab1(15516) human ... HSP90AA1(3320), HSP90AB1( 3326), rabbit, mouse, chicken, Sf9 cell line, wheat germ, human, rat, Achlya ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
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HSP 90 (4F10) Antibody sc-69703
... Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, HSP90AA1, 3320, 14q32.31, NM_001017963, NM_005348 · P07900 ...
http://www.scbt.com/datasheet-69703-hsp-90-4f10-antibody.htm...
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Human HSP90 Affinity Purified Polyclonal Ab
The inducible form, HSP90AA1, is a 737 amino acid protein also known as HSP90- Alpha, HSP90A, HSPC1, HSPCA, HSP89-Alpha and LAP2. HSP90AB1-1 ...
http://www.rndsystems.com/pdf/AF3286.pdf...
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