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ed
| Symbol: | ed | | Name(s): | echinoid | | Type: | protein-coding | | Organism: | Drosophila melanogaster | | Synonyms: | 1X5, CG12676, CG15424, CG16842, CT13476, CT35484, E(Elp)24D, E(Elp)[24D], l(2)k01102 | | Links: |
Pubmed,
Entrez Gene,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17936269 |
Data suggest that Echinoid mediates the dimerization of myosin VI/Jaguar in vivo which in turn regulates the reorganization and/or contraction of actin filaments to control changes in cell shape. |
| 14623819 |
role of Ed during embryonic nervous system development, as well as adult sensory bristle specification; interacts synergistically with the Notch signaling pathway |
| 14623820 |
antagonizes the bristle-promoting activity of the Egfr pathway, either by the enhancement of Notch signalling or, similar to the eye, by a more direct action on the Egfr pathway |
| 12668620 |
results suggest a model in which neuroglian acts as a heterophilic ligand and activator of echinoid, which in turn antagonizes EGFR signaling |
| 12835388 |
Results show that the cell surface protein Echinoid is required to moderate epidermal growth factor receptor signalling during R8 photoreceptor selection by the proneural gene atonal during Drosophila eye development. |
| 12835389 |
Data demonstrate that the transmembrane protein Echinoid is required to downregulate epidermal growth factor receptor activity in the developing Drosophila eye, ensuring a normal array of R8 photoreceptor neurons. |
| 15809032 |
Data show that, in the Drosophila wing disc epithelium, Echinoid is a component of adherens junctions that cooperates with DE-Cadherin in cell adhesion. |
| 14627723 |
Echinoid is associated with the cis-endocytosis of Delta, and is therefore linked to the signalling events. |
| 16858411 |
We propose that Ed and DGrip form a signaling complex, where competition between N-terminal and the C-terminal PDZDs of DGrip for Ed binding controls signaling function |
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