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HUS1
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18156970 |
Hus1 levels correlated significantly with the clinicopathologic factors of bad prognosis in epithelial ovarian tumors |
| 17855402 |
Human thymine DNA glycosylase activity is significantly stimulated by hHus1, hRad1, hRad9 separately, and by the 9-1-1 complex. |
| 17583730 |
Jab1 physically associates with the 9-1-1 complex (Rad1-Rad9-Hus1) |
| 17493829 |
we report successful tri-cistronic cloning, overexpression and purification of a three-protein complex of Rad9, Rad1 and Hus1 using a single hexa-histidine tag. |
| 15871698 |
The long-patch base excision machinery is an important target of the Rad9-Rad1-Hus1 complex, thus enhancing the quality control of DNA. |
| 11920544 |
downregulation by specific antisense oligonucleotides sensitizes human lung carcinoma cells to treatment with the DNA-damaging agent cisplatin |
| 17395641 |
Human NEIL1 DNA glycosylase activity is significantly stimulated by Hus1 and by the Rad9/Rad1/Hus1 heterotrimer. |
| 15314187 |
The human Rad9/Rad1/Hus1 complex interacts with and stimulates DNA polymerase beta activity. |
| 16216273 |
PCNA and the Rad9/Rad1/Hus1 complex can independently bind and activate Fen1; acetylation of Fen1 by p300-HAT abolished the stimulatory effect of the complex but not that of PCNA, suggesting a possible mechanism of regulation of this repair pathway |
| 15122316 |
HUS1 is an unstable protein that is actively degraded via the ubiquitin-proteasome pathway. Its expression can be stabilized by treating cells with proteasome-specific inhibitors. | →View more information from publications. |
Recent Publications on HUS1: |  |
DNA distress: just ring 9-1-1.
The Rad9-Hus1-Rad1 checkpoint clamp (9-1-1) is a central player in the... | 17th October, 2009
| Department of Biochemistry and Biophysics and Lineberger Comprehensive
| Curr Biol. 2009 Sep 15;19(17):R733-4.
DOI Direct Link |
Structure and functional implications of the human rad9-hus1-rad1 cell cycle checkpoint complex.
Cellular DNA lesions are efficiently countered by DNA repair in... | 15th October, 2009
| National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese
| J Biol Chem. 2009 Jul 31;284(31):20457-61. Epub 2009 Jun 17.
DOI Direct Link |
Cell cycle-dependent processing of DNA lesions controls localization of Rad9 to sites of genotoxic stress.
The Rad9/Rad1/Hus1 complex functions to facilitate the ATR-mediated... | 29th July, 2009
| Department of Cell Biology and Genetics, Cancer Genome Center, Erasmus MC,
| Cell Cycle. 2009 Jun 1;8(11):1765-74. Epub 2009 Jun 10.
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Crystal structure of the rad9-rad1-hus1 DNA damage checkpoint complex--implications for clamp loading and regulation.
Rad9, Rad1, and Hus1 form a heterotrimeric complex (9-1-1) that is loaded... | 25th July, 2009
| CR-UK DNA Repair Enzymes Group, Section of Structural Biology, The
| Mol Cell. 2009 Jun 26;34(6):735-45. Epub 2009 May 14.
DOI Direct Link |
Repair activities of human 8-oxoguanine DNA glycosylase are stimulated by the interaction with human checkpoint sensor Rad9-Rad1-Hus1 complex.
Rad9-Rad1-Hus1 (9-1-1) is a checkpoint protein complex playing roles in... | 21st July, 2009
| Department of Advanced Technology Fusion, Konkuk University, Seoul,
| DNA Repair (Amst). 2009 Oct 2;8(10):1190-200. Epub 2009 Jul 16.
DOI Direct Link |
→View more research publications. |
HUS1 results (if any) from reagent suppliers | 
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Hus1 (E-21) Antibody sc-30543
goat polyclonal IgG, 200 µg/ml; epitope mapping near the C-terminus of Hus1 of human origin; recommended for detection of Hus1 of human and, ...
http://www.scbt.com/datasheet-30543-hus1-e-21-antibody.html...
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Hus1 Antibody
Abgent develops powerful tools to profile posttranslational modifications related to cellular function and disease. Abgent antibodies target protein
kinases ...
http://www.abgent.com/products/catalog_no/AP6347a_Hus1_Antib...
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Hus1 (M-281) Antibody sc-8323
See how others have used Hus1 (M-281): sc-8323 antibody and or Hus1 (M-281) ... Interaction and colocalization of Rad9/Rad1/Hus1 checkpoint complex with ...
http://www.scbt.com/datasheet-8323-hus1-m-281-antibody.html...
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Antibodies to Check Point Proteins
H4664, Anti-HUS1 antibody produced in rabbit, (polyclonal), affinity isolated antibody, human ... HUS1(3364), human, IP, WB, pricing ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
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Hus Antibody / Hus Antibodies
Hus1 (E-21) Antibody, sc-30543, goat IgG, C-terminus (h), WB, IP, IF, ... Hus1 ( G-3) Antibody, sc-166440, mouse IgG1, 1-281 (m), WB, IP, IF, ELISA, m, r, h ...
http://www.scbt.com/table-hus.html...
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Purified Anti-Rad 17 Phosphorylated Ser645 Antibody - BioLegend
Rad17 is a component of the checkpoint clamp loader complex (Rad17/Rfc2-5) and recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin. ...
http://www.biolegend.com/purified-anti-rad-17-phosphorylated...
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Hus1 siRNA (m) sc-37546
Recommended Control Antibody 제품정보를 보시려면 카탈로그 번호를 클릭해 주세요. 제품명, 카탈로그 번호, 단위, 가격, 수량, 관심상품. Hus1 (M-281), sc-8323 ...
http://www.scbt.com/ko/datasheet-37546-hus1-sirna-m.html...
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