|
| |
IAPP
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 11318791 |
Observational study of genotype prevalence and gene-disease association. (HuGE Navigator) |
| 12588049 |
Observational study of gene-disease association. (HuGE Navigator) |
| 12679865 |
Observational study of gene-disease association. (HuGE Navigator) |
| 12706321 |
Observational study of gene-disease association. (HuGE Navigator) |
| 15878744 |
Observational study of gene-disease association. (HuGE Navigator) |
| 16950544 |
Observational study of genotype prevalence. (HuGE Navigator) |
| 17911343 |
Findings indicate the pancreatic beta-cell toxic effects of hIAPP depend on the propensity of IAPP to aggregate, but not on the consequence of protein overexpression. |
| 17722920 |
findings show that the I26P point mutatnt had a profound effect on the ability of hIAPP to form amyloid; the I26P point mutant was also a potent inhibitor of wild-type fibrillization |
| 17804609 |
Using IAPP transgenic mice, interventions that decreased both glycosaminoglycan synthesis and O-linked protein glycosylation reduced islet amyloid formation. |
| 17660321 |
Dynamic conformational changes observed for negatively charged lipid interfaces play an important role as the first steps of IAPP-induced membrane damage in type II diabetes. | →View more information from publications. |
Recent Publications on IAPP: |  |
Calcium-activated calpain-2 is a mediator of beta cell dysfunction and apoptosis in type 2 diabetes.
The islet in type 2 diabetes (T2DM) and the brain in neurodegenerative... | 29th October, 2009
| Univ. of California, Los Angeles, United States;
| J Biol Chem. 2009 Oct 28.
DOI Direct Link |
A critical assessment of the role of helical intermediates in amyloid formation by natively unfolded proteins and polypeptides.
Amyloidogenic proteins and polypeptides can be divided into two structural... | 29th October, 2009
| Division of Surgical Science, Department of Surgery, College of Physicians
| Protein Eng Des Sel. 2009 Aug;22(8):453-9. Epub 2009 Jul 12.
DOI Direct Link |
Helix stabilization precedes aqueous and bilayer-catalyzed fiber formation in islet amyloid polypeptide.
Islet amyloid polypeptide (IAPP) is an unstructured polypeptide hormone... | 21st October, 2009
| Department of Molecular Biophysics and Biochemistry, Yale University, New
| J Mol Biol. 2009 Oct 23;393(2):383-96. Epub 2009 Jul 30.
DOI Direct Link |
Annexin A5 Directly Interacts with Amyloidogenic Proteins and Reduces Their Toxicity.
Protein misfolding is a central mechanism for the development of... | 9th October, 2009
| Department of Biochemistry and Molecular Biology, Zilkha Neurogenetic
| Biochemistry. 2009 Nov 10;48(44):10568-10576.
DOI Direct Link |
A peptidomimetic approach to targeting pre-amyloidogenic states in type II diabetes.
Protein fiber formation is associated with diseases ranging from... | 26th September, 2009
| Department of Molecular Biophysics and Biochemistry, Yale University, 260
| Chem Biol. 2009 Sep 25;16(9):943-50.
DOI Direct Link |
→View more research publications. |
IAPP results (if any) from reagent suppliers | 
|
Amylin(20-29), Islet Amyloid Polypeptide, IAPP (20-29), cat
Peptides , Amyloid Peptides , Islet Amyloid Polypeptides (IAPP) ... IAPP, a putative polypeptide hormone, is a product of pancreatic beta-cells and the ...
http://www.anaspec.com/products/product.asp?id=46151...
|
 |
Anti-PDX-1 Polyclonal Antibody
... IAPP, and somatostatin gene transcription. Significant interest surrounds this proteins glucose-dependent regulation of insulin gene transcription. ...
http://www.bioreagents.com/products/productDetails/productDe...
|
 |
Amylin(20-29), Islet Amyloid Polypeptide, IAPP (20-29), cat
IAPP, a putative polypeptide hormone, is a product of pancreatic beta-cells ... IAPP has been increasingly studied as a simple model for factors governing ...
http://www.anaspec.com/products/product.asp?id=46238...
|
 |
Peptides, Peptide Products - GenWay Biotech Inc.
IAPP; - Diabetes-associated peptide; DAP; Amylin; Insulinoma amyloid peptide; Amylin; ... 06-271-83063, Amylin (IAPP) Feline Related Product Names: - IAPP;
...
http://www.genwaybio.com/all_peptides.php...
|
 |
Amylin(20-29), Islet Amyloid Polypeptide, IAPP (20-29), rat
This is amino acids 20 to 29 fragment of the rat islet amyloid polypeptide (IAPP ) or corresponding amylin fragment. This rat, hamster and degu IAPP sequence ...
http://www.anaspec.com/products/product.asp?id=45561...
|
 |
Amylin (H-50) Antibody sc-20936
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, IAPP, 3375, 12p12.1, NM_000415 ...
http://www.scbt.com/ko/datasheet-20936-amylin-h-50-antibody....
|
 |
[NMeG24, NMeI26] Human Islet Amyloid Polypeptide (IAPP) (22-27)
Peptides , Amyloid Peptides , Islet Amyloid Polypeptides (IAPP) , [NMeG24, NMeI26] Human Islet Amyloid Polypeptide (IAPP) (22-27); This amino acids 22 to
27 ...
http://www.anaspec.com/products/product.asp?id=50415...
|
 |
Search Bioportfolio and other Life Science Sites for IAPP,
or search for IAPP on BioPortfolio's antibody search engine.
This page has been viewed 104 times
Recent Search Terms used to find this page: iapp amylin | iapp amylin transgenic mice | amylin IAPP | .
Resources from the NCBI used on this page, NCBI's standard disclaimer applies.
|
