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ICAM1


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Symbol:ICAM1
Name(s):intercellular adhesion molecule 1 (CD54), human rhinovirus receptor
Type:protein-coding
Organism:Homo sapiens
Synonyms:BB2, CD54, P3.58
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18186794 Investigating a sample of living-unrelated donor kidney transplant pairs, study revealed an association between recipient K469 allele of ICAM1(P = 0.013) and K/K genotype (P = 0.042) with renal allograft acute rejection.
18233990 Observational study of gene-disease association. (HuGE Navigator)
18256065 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18233990 The ICAM-1 polymorphisms at codons G241R and E469K were associated with the disease susceptibility, and susceptibility to active decompensated cirrhosis is significantly increased in chronic HBV carriers carrying at least one R241-E469 haplotype.
17640650 Among women without a history of cardiovascular disease, sICAM-1 levels are predictive of events that reflect coronary atherosclerotic disease progression and vessel narrowing, but not those events associated with acute thrombosis/vessel occlusion
18260262 ICAM-1 plays an important role in the pathogenesis of nasal polyps
11072593 Observational study of gene-disease association. (HuGE Navigator)
11250042 Observational study of gene-disease association. (HuGE Navigator)
11354638 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
11361181 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
BINDCREB binding proteinHomo sapiens chromosome 19, reference assembly.CREBBP (CBP) interacts with the ICAM1 promoter.-Pubmed
HPRDFibrinogen, gamma chainintercellular adhesion molecule 1 precursor--Pubmed
HPRDfibrinogen, gamma chain isoform gamma-B precursorIntercellular adhesion molecule 1--Pubmed
HPRDIntercellular adhesion molecule 1interleukin 2 receptor, gamma precursor--Pubmed
HPRDIntercellular adhesion molecule 1integrin beta chain, beta 2 precursor--Pubmed
HPRDIntercellular adhesion molecule 1interleukin 2 receptor, alpha chain precursor--Pubmed
HPRDIntercellular adhesion molecule 1integrin alpha L precursor--Pubmed
HPRDIntercellular adhesion molecule 1moesin--Pubmed
HPRDIntercellular adhesion molecule 1ezrin--Pubmed
HPRDintercellular adhesion molecule 1 precursorInterleukin 2 receptor, alpha--Pubmed

Recent Publications on ICAM1:

Pubmed Logo
ICAM-1 is necessary for epithelial recruitment of gammadelta T cells and efficient corneal wound healing.
Wound healing and inflammation are both significantly reduced in mice that...
29th October, 2009
Section of Leukocyte Biology, Children's Nutrition Research Center, Room Am J Pathol. 2009 Aug;175(2):571-9. Epub 2009 Jul 16.
DOI Direct Link
Helicobacter pylori VacA activates NF-kappaB in T cells via the classical but not alternative pathway.
BACKGROUND: Helicobacter pylori secretes vacuolating cytotoxin (VacA) that...
8th October, 2009
Division of Molecular Virology and Oncology, Graduate School of Medicine, Helicobacter. 2009 Aug;14(4):271-9.
DOI Direct Link
A systematic meta-analysis of genetic association studies for diabetic retinopathy.
OBJECTIVE: Diabetic retinopathy is a sight-threatening microvascular...
1st October, 2009
Department of Ophthalmology, Flinders Medical Centre and Flinders Diabetes. 2009 Sep;58(9):2137-47. Epub 2009 Jul 8.
DOI Direct Link
SLP-76-ADAP adaptor module regulates LFA-1 mediated costimulation and T cell motility.
Although adaptor ADAP (FYB) and its binding to SLP-76 has been implicated...
29th September, 2009
Cell Signaling Section, Department of Pathology, Tennis Court Road, Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12436-41. Epub 2009 Jul 15.
DOI Direct Link
Effect of curcumin on nuclear factor kappaB signaling pathways in human chronic myelogenous K562 leukemia cells.
Curcumin, a natural product isolated from the plant Curcuma longa, has a...
24th September, 2009
Laboratoire de Biologie Moleculaire et Cellulaire du Cancer, Hopital Ann N Y Acad Sci. 2009 Aug;1171:436-47.
DOI Direct Link

View more research publications.

Clinical Trials:

Clinical Trials Logo
Frequency of ICAM-1 Polymorphisms in Obese Subjects

Patents:

Patents logo
US Patent No.Title
7408033 PRO5995 polypeptides
7438926 Methods for inhibiting decrease in transdermal drug flux by inhibition of pathway closure
7439019 Methods of identifying individuals at risk of perioperative bleeding, renal dysfunction
7439325 PRO6001 polypeptides
7447594 Molecular cardiotoxicology modeling

View more patents.

ICAM1 results (if any) from reagent suppliers

Google CSE Logo
CD54 (ICAM-1) Antibody #4915
CD54 (ICAM-1) Antibody detects endogenous levels of total CD54 protein. The antibody does not cross-react with other IgSF adhesion molecules. ...
http://www.cellsignal.com/products/4915.html...

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The Abcam catalog
ICAM1 antibodies. ... ICAM1 antibody [15.2] (Biotin). Flow Cyt. Mouse monoclonal ... ICAM1 antibody [1A29]. Flow Cyt, IP, WB, FuncS, IHC-Fr ...
http://www.abcam.com/index.html?t=55&pt=1&c=3290...

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ICAM-1 (15.2) Antibody sc-107
See how others have used ICAM-1 (15.2): sc-107 antibody and or ICAM-1 ... Western blot analysis of ICAM-1 expression in non-transfected: sc-117752 (A) and
...
http://www.scbt.com/datasheet-107-icam-1-15-2-antibody.html...

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ICAM1 antibody [15.2] (ab20) | Abcam
Mouse monoclonal [15.2] to ICAM1. ICAM1 is a 85-110 kDa single chain type 1 integral membrane glycoprotein with an extracellular domain of five ...
http://www.abcam.com/ICAM1-antibody-15-2-ab20.html...

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ICAM-1 (1H4) Antibody sc-51632
ICAM-1 (1H4) FITC, sc-51632 FITC, 100 tests in 2 ml ... See how others have used ICAM-1 (1H4): sc-51632 antibody and or ICAM-1 (1H4) antibody conjugates. ...
http://www.scbt.com/datasheet-51632-icam-1-1h4-antibody.html...

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ICAM1 antibody, ICAM1 [15.2] Antibody, Mouse Monoclonal Antibody
Buy quality mouse ICAM1 antibody (interacts with human - not yet tested in other ... Mouse monoclonal [15.2] to ICAM1; BB2; CD54; cell surface glycoprotein ...
http://www.genwaybio.com/product_info.php?products_id=191958...

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ICAM-1 (G-5) Antibody sc-8439
See how others have used ICAM-1 (G-5): sc-8439 antibody and or ICAM-1 (G-5) ... Western blot analysis of ICAM-1 expression in Jurkat whole cell lysate. ...
http://www.scbt.com/datasheet-8439-icam-1-g-5-antibody.html...

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