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ICAM2


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Symbol:ICAM2
Name(s):intercellular adhesion molecule 2
Type:protein-coding
Organism:Homo sapiens
Synonyms:CD102
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17609265 diminished ability of NK cells to kill HTLV-1-infected cells was the decreased ability of NK cells to adhere to HTLV-1-infected cells because of HTLV-1 p12(I)-mediated down-modulation of intercellular adhesion molecule 1 (ICAM-1) and ICAM-2.
15545280 N-Linked glycosylation regulate both conformation and immune related functions of ICAM receptors
15548573 The role of ICAM-2 has its recognition as potential therapeutic targets in human diseases.
14970226 soluble DC-SIGN bound to gp120-Fc more than 100- and 50-fold better than ICAM-2-Fc and ICAM-3-Fc, respectively. Binding sites are described.
12097408 Although ICAM-2 colocalizes with moesin and F-actin in microvilli of unstimulated endothelial cells, it is not involved in RhoA activation or cause stress fiber formation upon cross-linking.
17059578 pig and human ICAM-2 promoters exhibit many similarities
16857989 mutation of the serine phosphorylation site leads to inability of Mac-1 to become activated to bind the cellular ligands ICAM-1 and ICAM-2.
16987074 persistently elevated, serum levels of ICAM-2 throughout the various phases and types of Hemorrhagic fever with renal syndrome (HFRS) may be associated with the hyperfunctioning of the cellular immune response.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDIntercellular adhesion molecule 2moesin--Pubmed
HPRDIntercellular adhesion molecule 2radixin--Pubmed
HPRDIntercellular adhesion molecule 2CD209 molecule--Pubmed
HPRDintercellular adhesion molecule 2 precursorMoesin--Pubmed
HPRDintercellular adhesion molecule 2 precursorCD209 antigen--Pubmed
HPRDintercellular adhesion molecule 2 precursorRadixin--Pubmed
HPRDintercellular adhesion molecule 2 precursorintegrin beta chain, beta 2 precursor--Pubmed
HPRDintercellular adhesion molecule 2 precursorintegrin beta chain, beta 2 precursor--Pubmed
HPRDintercellular adhesion molecule 2 precursorintegrin alpha M precursor--Pubmed
HPRDintercellular adhesion molecule 2 precursorintegrin alpha M precursor--Pubmed

Recent Publications on ICAM2:

Pubmed Logo
Transcriptional profiles during the differentiation and maturation of monocyte-derived dendritic cells, analyzed using focused microarrays.
Dendritic cells (DC) are professional antigen-presenting cells capable of...
15th October, 2009
Institute of Biotechnology and Clinical Immunology Research Laboratory of Cell Mol Biol Lett. 2009;14(4):587-608. Epub 2009 Jun 25.
DOI Direct Link
From Midbody Protein-Protein Interaction Network Construction to Novel Regulators in Cytokinesis.
Midbody, a transient organelle-like structure, is known as central for...
6th October, 2009
Institute of Biotechnology in Medicine, Institute of Clinical Medicine, J Proteome Res. 2009 Oct 14.
DOI Direct Link
Intercellular adhesion molecule 1 (ICAM-1), but not ICAM-2 and -3, is important for dendritic cell-mediated human immunodeficiency virus type 1 transmission.
Dendritic cells (DCs) play a critical role in cell-to-cell-mediated...
7th May, 2009
Department of Microbiology and Molecular Genetics, Medical College of J Virol. 2009 May;83(9):4195-204. Epub 2009 Feb 11.
DOI Direct Link
Gene expression profiles of adipose tissue of obese rats after central administration of neuropeptide Y-Y5 receptor antisense oligodeoxynucleotides by cDNA microarrays.
To investigate the gene expression profiles of adipose tissue of obese...
14th April, 2009
Department of Pediatrics, Nanjing Maternity and Child Health Hospital of Peptides. 2008 Nov;29(11):2052-60. Epub 2008 Jul 4.
DOI Direct Link
Porcine DC-SIGN: molecular cloning, gene structure, tissue distribution and binding characteristics.
DC-SIGN, a human C-type lectin, is involved in the transmission of many...
13th March, 2009
Center for Molecular Medicine and Infectious Diseases, Department of Dev Comp Immunol. 2009 Apr;33(4):464-80. Epub 2008 Oct 23.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
5512660 Purified ICAM-2 and fragment thereof
6942981 Method of determining interactions with PDZ-domain polypeptides
7026121 Methods and compositions for diagnosing and monitoring transplant rejection
7034007 Low adenosine anti-sense oligonucleotide, compositions, kit & method for treatment of airway disorders associated with bronchoconstriction, lung inflammation, allergy(ies) & surfactant depletion
7083793 Tango 243 polypeptides and uses thereof

View more patents.

ICAM2 results (if any) from reagent suppliers

Google CSE Logo
PE Anti-human CD102 ICAM-2 Antibody Anti-CD102 - BioLegend
PE Anti-human CD102 ICAM-2 Antibody Anti-CD102 - CD102 is a 55 kD type I transmembrane glycoprotein, belongs to immunoglobulin superfamily, also known as
...
http://www.biolegend.com/pe-anti-human-cd102-icam-2-antibody...

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ICAM-2 (F-5) Antibody sc-9987
See how others have used ICAM-2 (F-5): sc-9987 antibody and or ICAM-2 (F-5) ... Western blot analysis of ICAM-2 expression in HL-60 whole cell lysate. ...
http://www.scbt.com/datasheet-9987-icam-2-f-5-antibody.html...

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BenderMed Systems: Anti-human ICAM-2 Antibody, Monoclonal FITC
Product Name, Anti-human ICAM-2 Antibody, Monoclonal. Analyte, ICAM-2. Species, Anti-human. Format, Antibody, Monoclonal. Cat. Nr. BMS109FI ...
http://www.bendermedsystems.com/products.php?nr=BMS109FI...

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ICAM-2 (H-159) Antibody sc-7933
See how others have used ICAM-2 (H-159): sc-7933 antibody and or ICAM-2 (H-159) ... Western blot analysis of ICAM-2 expression in NAMALWA whole cell lysate. ...
http://www.scbt.com/datasheet-7933-icam-2-h-159-antibody.htm...

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mouse ICAM-2 antibody, eFluorâ„¢ 450 conjugate
eBioscience technical data sheet for product 48-1021 eFluorâ„¢ 450 anti-mouse ICAM -2 (CD102) 3C4 (mIC2/4) antibody.
http://www.ebioscience.com/ebioscience/specs/antibody_48/48-...

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ICAM-2 (B-T1) Antibody sc-59789
Indirect FCM analysis of human peripheral blood leukocytes stained with ICAM-2 ( B-T1), followed by PE-conjugated goat anti-mouse IgG: sc-3738. ...
http://www.scbt.com/datasheet-59789-icam-2-b-t1-antibody.htm...

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ICAM2 antibody [CBR-IC2/2] (Biotin) (ab35268) | Abcam
ICAM2 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunogl...
http://www.abcam.com/icam2-antibody-cbr-ic2-2-biotin-ab35268...

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