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ICAM4
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 15847654 |
Observational study of genetic testing. (HuGE Navigator) |
| 17609430 |
LW play potentially pathophysiological roles in sickle cell disease |
| 16985175 |
We show that ICAM-4 functions as a ligand for the monocyte/macrophage-specific CD11c/CD18. Deletion of the individual immunoglobulin domains of ICAM-4 demonstrated that both its domains contain binding sites for CD11c/CD18. |
| 15355350 |
Different integrins bind to different but partly overlapping sites on ICAM4, and ICAM4 may accommodate multiple integrin receptors present on leukocytes, platelets and endothelial cells. |
| 12694184 |
binds to the I domains of the CD11a/CD18 and CD11b/CD18 leukocyte integrins |
| 16564726 |
Review. LW antigen contributes to RBC adhesion, thrombosis, and (in sickle cell disease) vaso-occlusion. |
| 12477717 |
ICAM-4 as the first red blood cells protein ligand of platelets that may have relevant physiological significance |
| 14551135 |
12 single amino-acid changes in ICAM4 affected the interaction of ICAM-4 with alpha(V) integrins |
| 15308566 |
LW on sickle but not on normal erythrocytes undergoes increased PKA-dependent serine phosphorylation as a result of activation. The major counter receptor for LW was identified as the alphavbeta3 integrin on ECs |
Recent Publications on ICAM4: |  |
Role and regulation of sickle red cell interactions with other cells: ICAM-4 and other adhesion receptors.
Erythrocytes containing primarily hemoglobin S (SS RBCs) are abnormally... | 16th September, 2008
| Department of Medicine and Duke Comprehensive Sickle Cell Center, Duke
| Transfus Clin Biol. 2008 Feb-Mar;15(1-2):23-8. Epub 2008 May 27.
DOI Direct Link |
Modulation of erythroid adhesion receptor expression by hydroxyurea in children with sickle cell disease.
BACKGROUND: We investigated adhesion receptor levels on red blood cells,... | 3rd June, 2008
| INSERM, U763, Paris.
| Haematologica. 2008 Apr;93(4):502-10. Epub 2008 Mar 5.
DOI Direct Link |
DCS-1, DCS-2, and DFV share amino acid substitutions at the extracellular RhD protein vestibule.
BACKGROUND: RhD and RhCE are structurally related to ammonium transporter... | 11th March, 2008
| Institute for Transfusion Medicine, University Hospital Ulm, Ulm Germany.
| Transfusion. 2008 Jan;48(1):25-33. Epub 2007 Sep 27.
DOI Direct Link |
Epinephrine-induced activation of LW-mediated sickle cell adhesion and vaso-occlusion in vivo.
Sickle red cell (SS RBC) adhesion is believed to contribute to the process... | 7th November, 2007
| Division of Hematology and Duke Comprehensive Sickle Cell Center,
| Blood. 2007 Oct 1;110(7):2708-17. Epub 2007 Jul 3.
DOI Direct Link |
Increased adhesion to endothelial cells of erythrocytes from patients with polycythemia vera is mediated by laminin alpha5 chain and Lu/BCAM.
Patients with polycythemia vera (PV) have a JAK2 (a cytosolic tyrosine... | 22nd September, 2007
| INSERM U665, Paris, France.
| Blood. 2007 Aug 1;110(3):894-901. Epub 2007 Apr 5.
DOI Direct Link |
→View more research publications. |
ICAM4 results (if any) from reagent suppliers | 
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ICAM-4 (C-20) Antibody sc-27685
goat polyclonal IgG, 200 µg/ml; epitope mapping within an extracellular domain of ICAM-4 of human origin; recommended for detection of precursor and mature ...
http://www.scbt.com/datasheet-27685-icam-4-c-20-antibody.htm...
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ICAM4 antibodies: Cell Biology > Apoptosis > Phagocytosis | Abcam
ICAM4 antibodies. ... ICAM4 antibodies. Code. Name. Applications (see key) & Reactivity (see key). Image Abreview Publication. ab67943 · ICAM4 antibody ...
http://www.abcam.com/index.html?t=258916&pt=1&c=2103&ei=&mu=...
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ICAM-4 siRNA (m) sc-146133
Click here for details. suitable control antibody: contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: ICAM-4 ...
http://www.scbt.com/datasheet-146133-icam-4-sirna-m.html...
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Pacific Blue Anti-mouse CD11b Antibody Anti-CD11b - BioLegend
Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen. ...
http://www.biolegend.com/pacific-blue-anti-mouse-cd11b-antib...
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ICAM Antibody / ICAM Antibodies
ICAM-4 (C-20) Antibody, sc-27685, goat IgG, extracellular (h), WB, IF, ELISA, human. ICAM-4 (M-20) Antibody, sc-27686, goat IgG, C-terminus (m), WB, IF, ...
http://www.scbt.com/table-icam.html...
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CD11a antibody, CD11a [I21/7] (FITC ) Antibody, Rat Monoclonal ...
Function: Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including ...
http://www.genwaybio.com/product_info.php?products_id=191829...
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CD11+CD18 antibody [24] (ab13219) | Abcam
CD11A is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction,
...
http://www.abcam.com/CD11-CD18-antibody-24-ab13219.html...
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