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ID1


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Symbol:ID1
Name(s):inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
Type:protein-coding
Organism:Homo sapiens
Synonyms:ID
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18072288 These data demonstrate that BMP-6 promotes migration and invasion of prostate cancer cells, potentially through activation of Id-1 and MMP activation.
18202790 Id-1 overexpression plays an important role in colorectal cancer progression.
18000500 The Id-1 may promote distant metastasis in oesophageal squamous cell carcinoma(ESCC), and both Id-1 may be used for prognostication for ESCC patients.
17855368 caveolin-1 is a novel Id-1 binding partner that mediates the function of Id-1 in promoting prostate cancer progression through activation of the Akt pathway leading to cancer cell invasion and resistance to anticancer drug-induced apoptosis
17916352 a novel tumorigenic role of Id-1 through reorganization of actin cytoskeleton and disassembly of cell-cell adhesion in response to TGF-beta1 in human prostate epithelial cells
17145808 Id-1 is a novel angiogenic factor for HCC metastasis and down-regulation of Id-1 may be a novel target to inhibit HCC metastasis through suppression of angiogenesis.
17599389 significantly enhanced expression of Id-1 has been detected in malignant prostate cell lines and in primary carcinomas; the increase in Id-1 expression was significantly associated with the increasing Gleason score of carcinomas
17565736 Id1 expression is primarily regulated at the transcriptional level in radial growth phase melanomas and expect that therapies that target Id1 gene expression may be useful in the treatment of Id-associated malignancies.
12719589 expression in human endothelial cells induced by Kaposi sarcoma-associated herpesvirus LANA protein, expression in Kaposi sarcoma tumor cells and in vivo
12823438 dysregulated Id-1 may not only contribute to delaying the senescence program in keratinocytes, it may also contribute to the escape of the relatively undifferentiated tumor cells in BCC from immune surveillance.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
BINDinhibitor of DNA binding 1 isoform acalcium/calmodulin-dependent serine protein kinaseCASK interacts with Id1.-Pubmed
BINDinhibitor of DNA binding 1 isoform bcalcium/calmodulin-dependent serine protein kinaseCASK interacts with Id1'.-Pubmed

Recent Publications on ID1:

Pubmed Logo
Scl regulates the quiescence and the long-term competence of hematopoietic stem cells.
The majority of long term reconstituting hematopoietic stem cells (LT-HSC)...
24th October, 2009
Institute of Research in Immunology and Cancer (IRIC), Montreal, Canada; Blood. 2009 Oct 22.
DOI Direct Link
Dysregulation of myeloid-specific transcription factors in congenital neutropenia.
Severe congenital neutropenia (CN) is a heterogeneous hematopoietic...
24th October, 2009
Department of Molecular Hematopoiesis, Hannover Medical School, Hannover, Ann N Y Acad Sci. 2009 Sep;1176:94-100.
DOI Direct Link
Abl Interactor 1 Regulates Src-Id1-Matrix Metalloproteinase 9 Axis and Is Required for Invadopodia Formation, Extracellular Matrix Degradation, and Tumor Growth of Human Breast Cancer Cells.
Abl interactor 1 (Abi1) is a key regulator of actin...
22nd October, 2009
Department of Internal Medicine. Carcinogenesis. 2009 Oct 20.
DOI Direct Link
Human tissue-engineered bone produced in clinically relevant amounts using a semi-automated perfusion bioreactor system: a preliminary study.
The aim of this study was to evaluate a semi-automated perfusion...
17th October, 2009
Institute for Biomedical Technology, University of Twente, 3720 AB J Tissue Eng Regen Med. 2009 Oct 15.
DOI Direct Link
Quantitative Transcription Factor Analysis of Undifferentiated Single Human Embryonic Stem Cells.
BACKGROUND: Human embryonic stem cells (hESCs) require expression of...
10th October, 2009
Lundberg Laboratory for Cancer, Department of Pathology, Sahlgrenska Clin Chem. 2009 Oct 8.
DOI Direct Link

View more research publications.

BioNews Results for ID1

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Gene Identified That Regulates Breast Cancer Metastasis
Biotech Daily:  Oct 13 2009 4:51PM Matching: id1
Gene That Regulates Breast Cancer Metastasis Identified By Wistar Researchers
Medical News Today:  Oct 7 2009 10:39AM Matching: id1
Researchers identify that KLF17 gene with Id1 gene can regulate breast cancer metastasis
News-Medical.Net:  Oct 6 2009 7:51AM Matching: id1
Researchers identify that KLF17 gene together with Id1 gene can regulate breast cancer metastasis
News-Medical.Net:  Oct 6 2009 5:02AM Matching: id1
Researchers Identify Gene That Regulates Breast Cancer Metastasis
Medical News Today:  Oct 6 2009 10:09AM Matching: id1
Promote your company here: BioNewsCast - Press Release Distribution

View more news.

Patents:

Patents logo
US Patent No.Title
7588771 Microorganisms for therapy
7594247 Method and apparatus for preparing and transmitting electronic program information and apparatus for producing electronic program guide from the electronic program information
7595168 Method of screening for substances useful for transdifferentiation of microglia into neurons
7595359 Cationic alkoxyamines and their use in producing nano particles from natural or synthetic clays
7596003 Electric power converter

View more patents.

ID1 results (if any) from reagent suppliers

Google CSE Logo
Id1 (C-20) Antibody sc-488
Western blot analysis of human recombinant Id1 (A,C) and Id1 His-tagged mouse ... Western blot analysis of Id1 expression in non-transfected: sc-110760 (A)
...
http://www.scbt.com/datasheet-488-id1-c-20-antibody.html...

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Bone Sialoprotein antibody [ID1.2] (ab58825) | Abcam
Mouse monoclonal [ID1.2] to Bone Sialoprotein. The protein encoded by the Bone Sialoprotein gene is a major structural protein of the bone matrix.
http://www.abcam.com/Bone-Sialoprotein-antibody-ID1-2-ab5882...

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Id1 (B-1) Antibody sc-133103
Id1 shRNA (h) Lentiviral Particles, sc-29356-V, 200 µl ... Western blot analysis of Id1 expression in non-transfected: sc-117752 (A) and human Id1 ...
http://www.scbt.com/datasheet-133103-id1-b-1-antibody.html...

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Id1 antibodies: Stem Cells > Hematopoietic Progenitors > Myeloid ...
Id1 antibodies. ... Id1 antibodies. Code. Name. Applications (see key) & Reactivity (see key). Image Abreview Publication. ab52998 · Id1 antibody ...
http://www.abcam.com/index.html?t=32960&pt=1&c=4515&ei=&mu=r...

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Id Antibody / Id Antibodies
Id1 (B-1) Antibody, sc-133103, mouse IgG2a, C-terminus (m), WB, IP, IF, ELISA, m , r, h ... Id1 (2456C1a) Antibody, sc-130018, mouse IgG1, WB, IP, human ...
http://www.scbt.com/table-id.html...

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www.hypromatrix.com Hypromatrix, Inc.
proteins include Id1, Id2, Id3 and Id4. They lack the basic region, ... Molecular weight of Id1: 15 kDa. Western blotting positive control: HeLa.
IMMUNOGEN ...
http://www.hypromatrix.com/Products/Primary_Antibody/Id1.pdf...

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BSPII (ID1.2) Antibody sc-73497
BSPII (ID1.2) Antibody sc-73497 BSPII (ID1.2) Antibody sc-73497.
http://www.scbt.com/datasheet-73497-bspii-id1.2-antibody.htm...

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Id1 inhibitor of DNA binding 1 | Inhibitor of DNA binding 1 protein | inhibitor of DNA binding antibody | inhibitor of DNA binding antibody | actin Id-1 | Id-1 OR Id1 inhibition | dna binding-1 | dna binding-1 | id1 abcam | .


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