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ID2
| Symbol: | ID2 | | Name(s): | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | GIG8, ID2A, ID2H, MGC26389 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17631285 |
Our data demonstrate that IL-1beta-induced Id2 expression in VSMC is mediated by the transcription factor Egr-1 in VSMC. |
| 18085637 |
Id2 commonly is overexpressed in highly proliferative T-cell lymphomas, and its expression may result from transcriptional activation of myc in these tumors. |
| 18000500 |
The high levels of Id-2 expression in both cytoplasmic and nuclear regions predicted longer patient survival, and Id-2 may be used for prognostication for oesophageal squamous cell carcinoma (ESCC) patients. |
| 17630394 |
RFX1 mediates the immediate early response of the Id2 gene by serum stimulation and suggest that the function of RFX1 is regulated intramolecularly in its suppression in growth-arrested cells. |
| 17431671 |
OLIG2 expression was predominant over ID2 expression in oligodendroglial tumors, while ID2 expression was predominant over OLIG2 expression in astrocytic tumors. |
| 16549780 |
enigma homolog enigma-like LIM domain protein is a restraining factor of the oncogenic activity of Id proteins in neural tumors |
| 12670915 |
Transcriptional regulation of ID2 by the MycN oncoprotein is unlikely to be a seminal molecular event resulting in a highly malignant neuroblastoma phenotype. |
| 15701714 |
Constitutive Id2 expression accelerates final maturation of both eosinophils and neutrophils, whereas inhibition of Id2 expression blocks differentiation of both lineages |
| 16223775 |
PU.1 and Id2 modulate lineage options of langerhans cell precursors, downstream of TGF-beta1. |
| 12447693 |
determination as a novel target of transcriptional activation by EWS-ETS fusion proteins in Ewing family tumors | →View more information from publications. |
Recent Publications on ID2: |  |
The Id2+ distal tip lung epithelium contains individual multipotent embryonic progenitor cells.
The conducting airways (bronchi and bronchioles) and peripheral gas... | 27th October, 2009
| Department of Cell Biology, Duke University Medical Center, Durham, NC
| Development. 2009 Nov;136(22):3741-5.
DOI Direct Link |
Interleukin-21 induces the differentiation of human umbilical cord blood CD34-lineage- cells into pseudomature lytic NK cells.
BACKGROUND: Umbilical cord blood (UCB) is enriched with transplantable... | 22nd October, 2009
| Department of Gynaecology, Catholic University Medical School, Rome,
| BMC Immunol. 2009 Aug 27;10:46.
DOI Direct Link |
The oligodendrocyte-specific G protein-coupled receptor GPR17 is a cell-intrinsic timer of myelination.
The basic helix-loop-helix transcription factor Olig1 promotes... | 20th October, 2009
| Department of Developmental Biology and Kent Waldrep Foundation Center for
| Nat Neurosci. 2009 Nov;12(11):1398-406. Epub 2009 Oct 18.
DOI Direct Link |
Human tissue-engineered bone produced in clinically relevant amounts using a semi-automated perfusion bioreactor system: a preliminary study.
The aim of this study was to evaluate a semi-automated perfusion... | 17th October, 2009
| Institute for Biomedical Technology, University of Twente, 3720 AB
| J Tissue Eng Regen Med. 2009 Oct 15.
DOI Direct Link |
Id2-, RORgammat-, and LTbetaR-independent initiation of lymphoid organogenesis in ocular immunity.
The eye is protected by the ocular immunosurveillance system. We show that... | 14th October, 2009
| Division of Mucosal Immunology, Department of Microbiology and Immunology,
| J Exp Med. 2009 Oct 26;206(11):2351-64. Epub 2009 Oct 12.
DOI Direct Link |
→View more research publications. |
Press Releases on ID2:
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| [video] Malcolm Philips, CEO of CDEX, Inc. Discusses First Shipments of ValiMed(TM) Model CCT System to International Customers on WallSt.net's 3-Minute Press Show |
25th August, 2008 |
CDEX, Inc. |
TUCSON, Ariz., Aug. 25 /PRNewswire-FirstCall/ -- CDEX, Inc.
(OTC Bulletin Board: CEXI), a technology development company, today announced
that the company's CEO, Malcolm Philips, is
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ID2 results (if any) from reagent suppliers | 
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Id Antibody / Id Antibodies
Id2 (2457C5a) Antibody, sc-81298, mouse IgG1, N-terminus (h), WB, IP, human. Id2 (C-20) Antibody, sc-489, rabbit IgG, C-terminus (m), WB, IP, IF, ELISA ...
http://www.scbt.com/table-id.html...
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Immunohistochemistry : ID2 - R&D Systems
This antibody specifically recognizes human ID2. This antibody has not yet been tested in other species. This antibody can be used for immunohistochemistry, ...
http://www.rndsystems.com/ihc_molecule_images.aspx?m=3806...
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ID2 antibodies: Stem Cells > Signaling Pathways > TGF beta ...
ID2 antibodies. ... ID2 antibody [2457C5a]. WB, Dot. Images. Mouse monoclonal. Reacts with: Hu. ab52116 · ID2 antibody, prediluted. IHC-P ...
http://www.abcam.com/index.html?t=8906&pt=1&c=3520&ei=&mu=ra...
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Id2 (m): 293T Lysate sc-120938
100 µg protein in 200 µl SDS-PAGE buffer; suitable as Western Blotting control for Id2 antibodies; mouse Id2 transfected 293T lysate; suitable control ...
http://www.scbt.com/datasheet-120938-id2-m-293t-lysate.html...
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Gel Handling
Z708690, Harris micro-punch replacement tip, I.D. 1.2 mm, pricing. Z708704, Harris micro-punch replacement tip, I.D. 2 mm, pricing ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
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Id2 (C-20) Antibody sc-489
Id2 (C-20) 抗体sc-489 Id2 (C-20) Antibody sc-489. ... Id2 (C-20): sc-489. Western blot analysis of Id2 expression in SK-N-MC whole cell lysate. ...
http://www.scbt.com/zh/datasheet-489-id2-c-20-antibody.html...
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Abgent - Transcription and Regulation Antibodies ...
AT2475aNEW, ID2 monoclonal antibody (M01), ELISA,RNAi-Ab,S-ELISA,WB-Re, H. AT2476aNEW, ID2 monoclonal antibody (M04), ELISA,S-ELISA,WB-Ce,WB-Re,WB-Tr, H
...
http://www.abgent.com/products/category/nuclear_signaling/tr...
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