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ABCB5
| Symbol: | ABCB5 | | Name(s): | ATP-binding cassette, sub-family B (MDR/TAP), member 5 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | ABCB5alpha, ABCB5beta, EST422562 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18202660 |
ABCB5 expression identifies melanoma stem cells and correlates with clinical disease progression in melanoma patients. In vivo targeting of ABCB5+ melanoma stem cells inhibits tumor growth in human to mouse melanoma xenotransplantation models. |
| 15760339 |
expression of ABCB 5alpha/beta might possibly provide two novel molecular markers for differential diagnosis of melanomas and constitute potential molecular targets for therapy of melanomas |
| 15899824 |
ABCB5 mediates chemoresistance in stem cell phenotype-expressing human malignant melanoma cells. |
| 12960149 |
ABCB5 P-glycoprotein functions include: Regulation of progenitor cell fusion; Regulation of cell membrane potential; Rhodamine-123 transport. |
ABCB5 results (if any) from reagent suppliers | 
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