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IDE


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Gene DB Home
Symbol:IDE
Name(s):insulin-degrading enzyme
Type:protein-coding
Organism:Homo sapiens
Synonyms:FLJ35968, INSULYSIN
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
16914266 Observational study of gene-disease association. (HuGE Navigator)
17192785 Meta-analysis of gene-disease association. (HuGE Navigator)
17293876 Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
17463249 Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
17496198 Observational study of gene-disease association. (HuGE Navigator)
17579348 Observational study of gene-disease association. (HuGE Navigator)
17804762 Observational study of gene-disease association. (HuGE Navigator)
17827400 Observational study of gene-disease association. (HuGE Navigator)
17913278 Meta-analysis of gene-disease association. (HuGE Navigator)
17953957 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDamyloid beta A4 protein precursor, isoform ainsulysin--Pubmed
HPRDandrogen receptor isoform 1Insulin degrading enzyme--Pubmed
HPRDGlucocorticoid receptorinsulysin--Pubmed
HPRDnuclear receptor subfamily 3, group C, member 1 isoform alphaInsulin degrading enzyme--Pubmed
HPRDinsulysinHuman preproinsulin-like growth factor II variant mRNA, and translated products--Pubmed
HPRDinsulysinHuman preproinsulin-like growth factor II variant mRNA, and translated products--Pubmed

Recent Publications on IDE:

Pubmed Logo
Interface wavelike deposits after descemet stripping automated endothelial keratoplasty.
To the Editor We greatly appreciated the recent article by Orina and...
3rd November, 2009
Institute of Vision and Optics, Department of Ophthalmology, University of Arch Ophthalmol. 2009 Oct;127(10):1389-90.
DOI Direct Link
Combined risk effects of IDE and NEP gene variants on Alzheimer disease.
Polymorphisms in genes encoding amyloid beta-peptide (A beta)-degrading...
30th October, 2009
Department of Neurology, Kuopio University and University Hospital, PO Box J Neurol Neurosurg Psychiatry. 2009 Nov;80(11):1268-70.
DOI Direct Link
Insulin degrading enzyme binds to the nonglycosylated precursor of varicella zoster virus gE protein found in the endoplasmic reticulum.
Insulin degradation enzyme (IDE) is a 110 kDa zinc-metalloprotease found...
30th October, 2009
Children's Hospital, University of Iowa, Iowa City, IA; Gade Institute, J Virol. 2009 Oct 28.
DOI Direct Link
PPARG, KCNJ11, CDKAL1, CDKN2A-CDKN2B, IDE-KIF11-HHEX, IGF2BP2 and SLC30A8 are associated with type 2 diabetes in a Chinese population.
BACKGROUND: Recent advance in genetic studies added the confirmed...
29th October, 2009
Department of Endocrinology and Metabolism, Shanghai Jiao Tong University PLoS One. 2009 Oct 28;4(10):e7643.
DOI Direct Link
The early elevation of interleukin 6 concentration in cerebrospinal fluid and delayed encephalopathy of carbon monoxide poisoning.
OBJECTIVE: This study was designed to investigate whether interleukin 6...
28th October, 2009
Department of Neurology, Kitasato University School of Medicine, Am J Emerg Med. 2009 Oct;27(8):992-6.
DOI Direct Link

View more research publications.

Press Releases on IDE:

BioPortfolio Logo
Impliant Announces the Addition of Vice President of Clinical and Regulatory Affairs to Executive Management Team 19th November, 2009 Impliant, Inc.

PRINCETON, N.J., Nov. 19 /PRNewswire/ -- Impliant, Inc., a developer of novel motion-sparing alternatives to traditional spinal fusion surgery, announced today that it has added Noel Rolon to

Results Presented from First Study Reviewing Convergent Approach to Treating Atrial Fibrillation at American Heart Association Scientific Sessions 19th November, 2009 nContact Surgical, Inc.

MORRISVILLE, N.C., Nov. 19 /PRNewswire/ -- nContact Surgical, Inc. ("nContact"), a leader in the investigation of devices for minimally-invasive treatment for heart conditions,

Endologix Receives IDE Approval for Fully Percutaneous Approach to EVAR 18th November, 2009 Endologix, Inc.

IRVINE, Calif., Nov. 18 /PRNewswire-FirstCall/ -- Endologix, Inc. (Nasdaq: ELGX), developer of minimally invasive treatments for aortic disorders, announced today that it has received

Cardiogenesis Reports Third Quarter 2009 Results 10th November, 2009 Cardiogenesis Corporation

IRVINE, Calif., Nov. 10 /PRNewswire-FirstCall/ -- Cardiogenesis Corporation (Pink Sheets: CGCP), a leading developer of surgical products used in the treatment of patients suffering

Facet Solutions Enrolls 100th Patient in US Pivotal IDE Study 9th November, 2009 Facet Solutions, Inc.

HOPKINTON, Mass., Nov. 9 /PRNewswire/ -- Facet Solutions, Inc. today announced that it has enrolled the 100th patient in its randomized, controlled ACADIA(TM) IDE study for lumbar spinal

BioNews Results for IDE

: RSS Logo
BioPortfolio Logo
Medical News: Low Birth Weight And Diabetes Have A Common Genetic Background
BioFind:  Nov 14 2009 1:42PM Matching: ide
Low Birth Weight And Diabetes Have A Common Genetic Background
Medical News Today:  Nov 14 2009 10:17AM Matching: ide
Takeda Pharmaceutical Company Limited - Financial And Strategic Analysis Review - New Report Published
OfficialWire:  Nov 14 2009 6:26AM Matching: ide
Trial Examines Whether Stem Cells Can Treat Critical Limb Ischemia
Diagnostic & Invasive Cardiology:  Nov 14 2009 2:10AM Matching: ide
Takeda Pharmaceutical Company Limited - Financial And Strategic Analysis Review - New Report Published
OfficialSpin:  Nov 14 2009 12:11AM Matching: ide
Promote your company here: BioNewsCast - Press Release Distribution

View more news.

Clinical Trials:

Clinical Trials Logo
Post-PMA Approval Study: 10 Year Follow-Up IDE Subjects

Patents:

Patents logo
US Patent No.Title
7610345 Reduced traceability electronic message system and method
7611742 Reduced fat and carbohydrate milk product and process for manufacturing such milk product
7612054 Dibenzo[b,f]oxepine-10-carboxamides and pharmaceutical uses thereof
7612075 Substituted oxoazaheterocyclyl compounds
7612076 Piperazinyl-pyridine derivatives

View more patents.

IDE results (if any) from reagent suppliers

Google CSE Logo
Insulin degrading enzyme / IDE antibody (ab25970) | Abcam
Rabbit polyclonal to Insulin degrading enzyme / IDE. Insulysin was identified nearly a century ago as an enzyme responsible for the degradation of insulin ...
http://www.abcam.com/Insulin-degrading-enzyme-IDE-antibody-a...

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IDE Antibody (Center)
IDE Antibody (Center) Stem Cell, IDE Antibody (Center)
http://www.abgent.com/products/catalog_no/AP1455c...

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IDE (A-23) Antibody sc-130784
rabbit polyclonal IgG, 100µg/ml; recommended for detection of IDE of human ... IDE (A-23): sc-130784. Western blot analysis of IDE expression in A-375 whole
...
http://www.scbt.com/datasheet-130784-ide-a-23-antibody.html...

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Insulin degrading enzyme / IDE antibody - Carboxyterminal end ...
Rabbit polyclonal to Insulin degrading enzyme / IDE - Carboxyterminal end. Insulysin was identified nearly a century ago as an enzyme responsible for the
...
http://www.abcam.com/Insulin-degrading-enzyme-IDE-antibody-C...

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Insulysin/IDE - R&D Systems
Insulysin, or insulin-degrading enzyme (IDE), is a zinc metallopeptidase of the inverzincin family. IDE is primarily located in the cytosol, ...
http://www.rndsystems.com/molecule_detail.aspx?m=2648...

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Insulin degrading enzyme / IDE antibodies: Neuroscience ...
Insulin degrading enzyme / IDE antibodies. ... Insulin degrading enzyme / IDE antibody. IHC-P, IHC-FoFr, WB. Images · Customer Abreviews: 3 stars (out of 5)
...
http://www.abcam.com/index.html?t=125432&pt=1&c=433&ei=&mu=r...

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Recombinant Human Insulysin/IDE
was specifically disrupted in mice, IDE / animals developed hyperinsulinemia and glucose intolerance ... evidence is consistent with the hypotheses that IDE ...
http://www.rndsystems.com/pdf/2496-ZN.pdf...

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