Wednesday November 25 2009 | Biotechnology feed | All feeds

BioPortfolio Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease

IDH2


Suggest Content
Advertise Here
Gene DB Home
Symbol:IDH2
Name(s):isocitrate dehydrogenase 2 (NADP+), mitochondrial
Type:protein-coding
Organism:Homo sapiens
Synonyms:ICD-M, IDH, IDHM, IDP, mNADP-IDH
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18096511 These results indicate that IDPm may play an important role in regulating the apoptosis induced by heat shock.
17854715 IDPm may play an important role in regulating apoptosis induced by TNF-alpha and anticancer drugs and the sensitizing effect of IDPm siRNA on the apoptotic cell death of HeLa cells offers the possibility of developing a modifier of cancer chemotherapy.

Recent Publications on IDH2:

Pubmed Logo
IDH1 and IDH2 hotspot mutations are not found in canine glioma.
Glioblastoma is the most common and highest-grade brain tumor, causing...
31st October, 2009
The Preston Robert Tisch Brain Tumor Center and The Pediatric Brain Tumor Int J Cancer. 2009 Oct 29.
DOI Direct Link
Advances in the genetics of glioblastoma: are we reaching critical mass?
Glioblastoma is the most common and highest-grade brain tumor, causing...
27th October, 2009
Neuro-Oncology Division, Neurology Department, University of Virginia, Nat Rev Neurol. 2009 Aug;5(8):419-26. Epub 2009 Jul 14.
DOI Direct Link
Analysis of IDH1 and IDH2 mutations in Japanese glioma patients.
A recent study reported on mutations in the active site of the isocitrate...
10th October, 2009
Department of Neurosurgery, Tohoku University Graduate School of Medicine, Cancer Sci. 2009 Oct;100(10):1996-8.
DOI Direct Link
Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas.
Somatic mutations in the IDH1 gene encoding cytosolic NADP+-dependent...
9th October, 2009
Department of Neuropathology, Institute of Pathology, Acta Neuropathol. 2009 Oct;118(4):469-74. Epub 2009 Jun 25.
DOI Direct Link
Disulfide bond formation in yeast NAD+-specific isocitrate dehydrogenase.
The tricarboxylic acid cycle NAD+-specific isocitrate dehydrogenase (IDH)...
6th October, 2009
Department of Biochemistry, University of Texas Health Science Center, San Biochemistry. 2009 Sep 22;48(37):8869-78.
DOI Direct Link

View more research publications.

BioNews Results for IDH2

: RSS Logo
BioPortfolio Logo
Two Gene Mutations Linked to Most Common Brain Cancers - 2/19/09
Johns Hopkins Medicine:  Oct 16 2009 8:17PM Matching: idh2
Two Gene Mutations Linked to Most Common Brain Cancers - 2/19/09
Johns Hopkins Medicine:  Oct 16 2009 8:16PM Matching: idh2

Patents:

Patents logo
US Patent No.Title
6433262 Plants and seeds of corn variety I889291
6747137 Nucleic acid sequences relating to Candida albicans for diagnostics and therapeutics
6756527 Inbred corn plant 5750 and seeds thereof
6806409 Plants and seeds of corn variety 1501150
6806410 Plants and seeds of corn variety I390186

View more patents.

IDH2 results (if any) from reagent suppliers

Google CSE Logo
IDH2 antibody (ab55271) | Abcam
Mouse monoclonal to IDH2. IDH2 is an NADP-dependent isocitrate dehydrogenase which catalyzes the oxidative decarboxylation of isocitrate to 2-oxoglutarate.
http://www.abcam.com/IDH2-antibody-ab55271.html...

Thumbshot
IDH2 (BA-19) Antibody sc-100594
mouse monoclonal IgG1, 50 µg/0.5 ml; raised against recombinant IDH2 of human ... IDH2 (BA-19): sc-100594. Immunoperoxidase staining of formalin-fixed, ...
http://www.scbt.com/datasheet-100594-idh2-ba-19-antibody.htm...

Thumbshot
IDH2 monoclonal antibody (M01)
Immunoperoxidase of monoclonal antibody to IDH2 ( Cat # AT2479a ) on formalin- fixed paraffin-embedded human colon. [antibody concentration 3 ug/ml] ...
http://www.abgent.com/products/catalog_no/AT2479a_IDH2_monoc...

Thumbshot
IDH2 (W-16) Antibody sc-55668
IDH2 shRNA (h) Lentiviral Particles, sc-62487-V, 200 µl ... Western blot analysis of IDH2 expression in rat heart (A) and mouse heart (B) tissue extracts
. ...
http://www.scbt.com/datasheet-55668-idh2-w-16-antibody.html...

Thumbshot
IDH1 Antibody #3997
The antibody does not cross react with IDH2. ... IDH2 and 3 are mitochodrial enzymes that also function in the Krebs cycle. IDH1 is inactivated by ...
http://www.cellsignal.com/products/3997.html...

Thumbshot
IDH Antibody / IDH Antibodies
IDH2 (L-15) Antibody, sc-55664, goat IgG, C-terminus (h), WB, IF, ELISA, m, h, ... IDH2 (N-16) Antibody, sc-55666, goat IgG, N-terminus (h), WB, IF, ELISA ...
http://www.scbt.com/table-idh.html...

Thumbshot
IDH1 Antibody
IDH2 and 3 are mitochodrial enzymes that also function in the Krebs cycle ... cross react with IDH2. Source/Purification: Polyclonal antibodies are produced
...
http://www.cellsignal.com/pdf/3997.pdf...

Thumbshot

Search Bioportfolio and other Life Science Sites for IDH2, or search for IDH2 on BioPortfolio's antibody search engine.
This page has been viewed 101 times
Recent Search Terms used to find this page: .


Resources from the
NCBI used on this page, NCBI's standard disclaimer applies.

 

Nothing in this website should be used in place of personal medical advice from your own qualified medical practitioner.

All rights reserved. All other trademarks recognized.
Copyright 1997-2009 - BioPortfolio Limited.