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IDH3A


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Symbol:IDH3A
Name(s):isocitrate dehydrogenase 3 (NAD+) alpha
Type:protein-coding
Organism:Homo sapiens
Synonyms:-
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
16737955 active sites of the human NAD-IDH are shared between alpha and gamma subunits and between alpha and beta subunits
14555658 for IDH, a normal alpha subunit is required for catalytic activity and alpha-Arg88 likely participates in the isocitrate site, whereas the beta and gamma subunits have roles in the nucleotide functions of this allosteric enzyme
17432878 Asp181 is essential for nicotinamide-adenine dinucleotide (NAD)-specific IDH alpha subunit catalysis and may also facilitate the binding of substrates.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDIsocitrate dehydrogenase 3, alpha subunitisocitrate dehydrogenase 3 gamma isoform a precursor--Pubmed
HPRDisocitrate dehydrogenase 3 alpha precursorIsocitrate dehydrogenase 3 gamma subunit--Pubmed
HPRDisocitrate dehydrogenase 3 alpha precursorisocitrate dehydrogenase 3, beta subunit isoform a precursor--Pubmed
HPRDisocitrate dehydrogenase 3 alpha precursorisocitrate dehydrogenase 3, beta subunit isoform a precursor--Pubmed

Recent Publications on IDH3A:

Pubmed Logo
Novel mitochondrial substrates of omi indicate a new regulatory role in neurodegenerative disorders.
The mitochondrial protease OMI (also known as HtrA2) has been implicated...
19th September, 2009
Department of Neurological Surgery, Cornell University, Weill Medical PLoS One. 2009 Sep 18;4(9):e7100.
DOI Direct Link
LPS decreases fatty acid oxidation and nuclear hormone receptors in the kidney.
Inflammation produces marked changes in lipid metabolism, including...
23rd October, 2008
Metabolism Section, Department of Veterans Affairs Medical Center, San J Lipid Res. 2008 Oct;49(10):2179-87. Epub 2008 Jun 23.
DOI Direct Link
Fine mapping of the keratoconus with cataract locus on chromosome 15q and candidate gene analysis.
PURPOSE: To report the fine mapping of the keratoconus with cataract locus...
27th June, 2006
Department of Medical Genetics, Queen's University of Belfast, Royal Mol Vis. 2006 May 12;12:499-505.

Patents:

Patents logo
US Patent No.Title
7608395 Systemic lupus erythematosus diagnostic assay
7598031 Method for the detection of gene transcripts in blood and uses thereof
7588771 Microorganisms for therapy
7588767 Microorganisms for therapy
7208313 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector

View more patents.

IDH3A results (if any) from reagent suppliers

Google CSE Logo
IDH3A antibody (ab58641) | Abcam
Rabbit polyclonal to IDH3A. Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two ...
http://www.abcam.com/IDH3A-antibody-ab58641.html...

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IDH Antibody / IDH Antibodies
IDH3A (E-20) Antibody, sc-55670, goat IgG, Internal (h), WB, IP, IF, ELISA, m, r , h, cow ... IDH3A shRNA Plasmid (h): sc-62489-SH. IDH3A shRNA (h) ...
http://www.scbt.com/table-idh.html...

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IDH3A antibodies: Signal Transduction > Metabolism > Mitochondrial ...
IDH3A antibodies. ... Image Abreview Publication. ab58641 · IDH3A antibody. IHC- P, WB, ELISA. Images. Rabbit polyclonal ...
http://www.abcam.com/index.html?t=233676&pt=1&c=2252&ei=&mu=...

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IDH3A siRNA (m) sc-62490
Click here for details. suitable control antibody: IDH3A (E-20): sc-55670; RT- PCR Primer also available: IDH3A (m)-PR: sc-62490, 20 µl ...
http://www.scbt.com/ko/datasheet-62490-idh3a-sirna-m.html...

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Antibody Products - Protein and Antibody Solutions Provider - GenWay
18-003-43731, IDH3A (isocitrate dehydrogenase 3 (NAD+) alpha) Related Product Names: - IDH3A; - EC 1.1.1.41; Isocitric dehydrogenase; NAD(+)-specific ICDH;
...
http://www.genwaybio.com/all_polyclonal_antibodies.php?fl=I...

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IDH3A siRNA (h) sc-62489
Click here for details. suitable control antibody: IDH3A (E-20): sc-55670; sqRT- PCR Primer also available: IDH3A (h)-PR: sc-62489, 20 µl ...
http://www.scbt.com/ko/datasheet-62489-idh3a-sirna-h.html...

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Isocitrate dehydrogenase (IDH3) Antibody (C-term)
Isocitrate dehydrogenase [NAD] subunit alpha; mitochondrial [Precursor]; Isocitric dehydrogenase; NAD(+)-specific ICDH; IDH3A; ...
http://www.abgent.com/products/catalog_no/AP1927a...

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