Tuesday November 24 2009 | Biotechnology feed | All feeds

IDH3B

Symbol:	IDH3B
Name(s):	isocitrate dehydrogenase 3 (NAD+) beta
Type:	protein-coding
Organism:	Homo sapiens
Synonyms:	FLJ11043, H-IDHB, MGC903
Links:	Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications
Publication Link	Summary of findings
15653693	IDPm activity appears to be modulated through enzymatic glutathionylation and deglutathionylation during oxidative stress
16737955	active sites of the human NAD-IDH are shared between alpha and gamma subunits and between alpha and beta subunits
17432878	Asp192 is needed for optimal affinity of IDH beta subunit for nicotinamide-adenine dinucleotide (NAD) substrate, but is not critical for catalysis.

Interacting gene products
Interaction Type	Gene 1	Gene 2	Interaction description	Complex	Publication Link
HPRD	isocitrate dehydrogenase 3 alpha precursor	isocitrate dehydrogenase 3, beta subunit isoform a precursor	-	-	Pubmed
HPRD	isocitrate dehydrogenase 3 alpha precursor	isocitrate dehydrogenase 3, beta subunit isoform a precursor	-	-	Pubmed
HPRD	Isocitrate dehydrogenase 3 beta	isocitrate dehydrogenase 3 gamma isoform a precursor	-	-	Pubmed
HPRD	isocitrate dehydrogenase 3, beta subunit isoform a precursor	Isocitrate dehydrogenase 3 gamma subunit	-	-	Pubmed

Recent Publications on IDH3B:
Insights from retinitis pigmentosa into the roles of isocitrate dehydrogenases in the Krebs cycle. Here we describe two families with retinitis pigmentosa, a hereditary...	31st October, 2008	Ocular Molecular Genetics Institute, Harvard Medical School, Massachusetts	Nat Genet. 2008 Oct;40(10):1230-4. Epub 2008 Sep 21. DOI Direct Link
Gene expression studies of hepatitis virus-induced woodchuck hepatocellular carcinoma in correlation with human results. The lack of good molecular markers for diagnosis as well as treatment...	1st February, 2007	Department of Biomedical Engineering, Case Western Reserve University,	Int J Oncol. 2007 Jan;30(1):33-44.

Patents:
US Patent No.	Title
7608395	Systemic lupus erythematosus diagnostic assay
7531300	Method of diagnosing breast cancer
7485468	Molecular targets and compounds, and methods to identify the same, useful in the treatment of joint degenerative and inflammatory diseases
7235358	Methods and compositions for diagnosing and monitoring transplant rejection
7026121	Methods and compositions for diagnosing and monitoring transplant rejection
→View more patents.

IDH3B results (if any) from reagent suppliers

IDH Antibody / IDH Antibodies IDH3B (M-17) Antibody, sc-55674, goat IgG, C-terminus (m), WB, IP, IF, ELISA, m, r, pig ... IDH3B shRNA Plasmid (h): sc-62491-SH. IDH3B shRNA (h) ... http://www.scbt.com/table-idh.html...
IDH3B siRNA (h) sc-62491 Click here for details. contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: IDH3B (h)-PR: sc-62491, 20 µl ... http://www.scbt.com/ja/datasheet-62491-idh3b-sirna-h.html...
IDH3B (M-17) Antibody sc-55674 IDH3B (M-17) Anticorps sc-55674 IDH3B (M-17) Antibody sc-55674. http://www.scbt.com/fr/datasheet-55674-idh3b-m-17-antibody.h...
IDH3B (M-17) Antibody sc-55674 IDH3B (M-17) 抗体 sc-55674 IDH3B (M-17) Antibody sc-55674. http://www.scbt.com/ja/datasheet-55674-idh3b-m-17-antibody.h...

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