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IFNA1
| Symbol: | IFNA1 | | Name(s): | interferon, alpha 1 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | IFL, IFN, IFN-ALPHA, IFNA13, IFNA@, MGC138207, MGC138505, MGC138507 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 11315919 |
Observational study of gene-disease association. (HuGE Navigator) |
| 12761564 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17572490 |
In short term blast lines from patients with AML, additive effects of IFN-alpha and LPS on Caspase-8 dependent apoptosis was observed only with few samples |
| 18184042 |
impairment of IFN-alpha production may be linked to an increased cancer risk and dysfunction of the IFN system is associated with cancer. Assessment of IFN-alpha production can be a potential test for the early detection of cancer in humans. |
| 18050196 |
IFNalpha activity and BAFF levels are elevated in the plasma of patients with Sjogren's syndrome compared with healthy controls. |
| 17517919 |
Data describe the species specificity of IFN-alphas, the residues in murine IFN-alpha4 that preclude strong affinity interactions with human IFNAR1 and 2, and residues in human IFN-alpha8 that resemble a receptor interactive domain in murine IFN-alpha4. |
| 17956986 |
IFN-alpha produced after HIV-induced Toll-like receptor 7 stimulation was responsible for TRAIL expression and the down-regulation of both CXCR4 and CCR5 by IKpDC |
| 17968925 |
depletion of endothelial progenitor cells caused by excessive IFN-I may be linked to endothelial dysfunction and increased cardiovascular risk in systemic lupus erythematosus |
| 17968926 |
Dermatomyositis and polymyositis are diseases characterized by the systemic overexpression of IFNalpha/beta-inducible genes |
| 17911607 |
Addition of interferon alpha to monocyte-derived dendritic cells or pretreatment with Toll-like receptor ligands protects against infection and the cytopathic effects of avian influenza H5N1 virus. | →View more information from publications. |
Recent Publications on IFNA1: |  |
Genetic association of interferon-alpha subtypes 1, 2 and 5 in systemic lupus erythematosus.
In this study, the association between the systemic lupus erythematosus... | 25th August, 2009
| Lupus Research Unit, Department of Microbiology, Faculty of Medicine,
| Tissue Antigens. 2008 Dec;72(6):588-92. Epub 2008 Oct 18.
DOI Direct Link |
Atlantic cod (Gadus morhua L.) possesses three homologues of ISG15 with different expression kinetics and conjugation properties.
Two new interferon stimulated gene 15 (ISG15) family members were... | 28th July, 2009
| Department of Marine Biotechnology, Norwegian College of Fishery Science,
| Dev Comp Immunol. 2009 Dec;33(12):1239-46. Epub 2009 Aug 4.
DOI Direct Link |
Atlantic salmon IPS-1 mediates induction of IFNa1 and activation of NF-kappaB and localizes to mitochondria.
The striking difference in evolution of type I IFN genes of fish and... | 7th July, 2009
| Department of Marine Biotechnology, Norwegian College of Fishery Science,
| Dev Comp Immunol. 2009 Nov;33(11):1196-204. Epub 2009 Jul 10.
DOI Direct Link |
Tamoxifen induces expression of immune response-related genes in cultured normal human mammary epithelial cells.
Use of tamoxifen is associated with a 50% reduction in breast cancer... | 24th March, 2009
| Carcinogen-DNA Interactions Section, LCBG, CCR, National Cancer Institute,
| Cancer Res. 2009 Feb 1;69(3):1150-5. Epub 2009 Jan 20.
DOI Direct Link |
An antiserum against Atlantic salmon IFNa1 detects IFN and neutralizes antiviral activity produced by poly I:C stimulated cells.
Type I interferons (IFNs) play a crucial role in innate immune responses... | 13th March, 2009
| Department of Marine Biotechnology, Norwegian College of Fishery Science,
| Dev Comp Immunol. 2009 Apr;33(4):638-45. Epub 2008 Dec 6.
DOI Direct Link |
→View more research publications. |
IFNA1 results (if any) from reagent suppliers | 
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human IFNa1 antibody, Carrier-Free conjugate
eBioscience technical data sheet for product 34-8318 Carrier-Free Recombinant Human IFN-alpha1 (Interferon-alpha1, IFN-a1) antibody.
http://www.ebioscience.com/ebioscience/specs/antibody_34/34-...
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PBL InterferonSource Human Interferon Alpha Antibody Specificity
... human IFN alpha D (IFNa1). Antibodies reacting with these subtypes often do not bind effectively to many of the other human interferon alpha subtypes. ...
http://www.interferonsource.com/New_InterferonSource/Antibod...
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human IFNa1 antibody, Single-Use ELISA RSG Standard conjugate
eBioscience technical data sheet for product 39-8318 Single-Use ELISA RSG Standard Recombinant Human IFN-alpha1 antibody.
http://www.ebioscience.com/ebioscience/specs/antibody_39/39-...
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IFN-α (5D4) Antibody sc-80996
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, IFNA1, 3439, 9p21.3, P01562 ...
http://www.scbt.com/datasheet-80996-ifn-alpha-5d4-antibody.h...
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eBioscience: Product listing for Human Cytokine Antibody Sets for ...
Human IFN-alpha1 (IFNa1, Interferon-alpha 1, IFN-a1) ELISA Ready-SET-Go! RSG, -- , ELISAset, RUO. 88-7399 · Prices & Data Sheet Human CCL2 (MCP-1, MCP1, ...
http://www.ebioscience.com/ebioscience/dept.asp?dept_id=920...
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IFN-α (FL-189) Antibody sc-20106
Spezies, Gen, Gen ID, Chromosomaler Locus, mRNA (Isoform) Accession #, Protein Accession #, OMIM™ Nummer. Human, IFNA1, 3439, 9p21.3, NM_024013 · P01562 ...
http://www.scbt.com/de/datasheet-20106-ifn-alpha-fl-189-anti...
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Cytokine Kits Antibody and Reagent Products Catalog Number 88
88-7389 Human IFN-alpha1 (IFNa1, Interferon-alpha 1, IFN-a1) ELISA Ready-SET-Go! RSG; 88-7391 Mouse CCL2 (MCP-1, MCP1, MCAF) ELISA Ready-SET-Go! ...
http://www.ebioscience.com/ebioscience/sitemap/antibody_88.h...
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