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IFNA2
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 16920161 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18032529 |
Recombinant human IFN-alpha 2b causes programmed cell death in nondiseased renal epithelial cells. IFN-alpha-induced apoptosis is directed by an extrinsic death receptor signaling pathway, amplified by an intrinsic mitochondrial pathway. |
| 17880940 |
IFNalpha is able to interfere with IL-6 signaling by inhibiting STAT3 activity and the abrogation of STAT3 activity accounts for the ability of IFNalpha to induce apoptosis in myeloma cells. |
| 18005734 |
we propose that HIV-1 expresses Vpu to counteract an IFNalpha-induced, general host defense that inhibits dissemination of enveloped virions from the surface of infected cells. |
| 16697656 |
In vivo induction of ITGA-11 is detected in spleen and lungs of human recombinant IFN-alpha 2-treated BALB/c mice. |
| 16171819 |
Data describe the mapping of the complete binding region of IFNAR1 on IFNalpha2 using a panel of 21 single alanine mutant proteins. |
| 17116765 |
Plasmacytoid dendritic cells in atherosclerotic plaque sense microbial motifs and amplify cytolytic T-cell functions. IFN-alpha emerged as a potent regulator of T-cell function. |
| 17477817 |
study reports that, in addition to promoting T cell chemotaxis, IFN-alpha2 enhances T cell adhesion to integrin ligands, which is associated with integrin clustering on the T cell surface and enhanced conjugate formation with dendritic cells |
| 15004750 |
Possession of the IFNA17 polymorphism (551T-->G), with higher levels of IFN-alpha significantly increases the risk of sarcoidosis. |
| 16920161 |
Findings indicate that the deletion in the promoter of the IFN-alpha-2 gene reduces the transcription of this gene in vitro and this could also be one cause of susceptibility to hepatitis B. | →View more information from publications. |
Recent Publications on IFNA2: |  |
Genetic association of interferon-alpha subtypes 1, 2 and 5 in systemic lupus erythematosus.
In this study, the association between the systemic lupus erythematosus... | 25th August, 2009
| Lupus Research Unit, Department of Microbiology, Faculty of Medicine,
| Tissue Antigens. 2008 Dec;72(6):588-92. Epub 2008 Oct 18.
DOI Direct Link |
A globally occurring indel polymorphism in the promoter of the IFNA2 gene is not associated with severity of malaria but with the positivity rate of HCV.
BACKGROUND: Type I Interferons (IFNs) are well known cytokines which exert... | 20th March, 2009
| Department of Parasitology, Institute for Tropical Medicine, Tubingen,
| BMC Genet. 2008 Dec 3;9:80.
DOI Direct Link |
New origins of DNA replication identified near the human IFNA2 gene.
Interferon regulatory factor (IRF) genes encode DNA-binding proteins that... | 17th March, 2009
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| Cell Cycle. 2008 Dec 15;7(24):3949-51. Epub 2008 Dec 21.
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An antiserum against Atlantic salmon IFNa1 detects IFN and neutralizes antiviral activity produced by poly I:C stimulated cells.
Type I interferons (IFNs) play a crucial role in innate immune responses... | 13th March, 2009
| Department of Marine Biotechnology, Norwegian College of Fishery Science,
| Dev Comp Immunol. 2009 Apr;33(4):638-45. Epub 2008 Dec 6.
DOI Direct Link |
Identification of an Atlantic salmon IFN multigene cluster encoding three IFN subtypes with very different expression properties.
A cluster of 11 interferon (IFN) genes were identified in the Atlantic... | 13th March, 2009
| Department of Marine Biotechnology, Norwegian College of Fishery Science,
| Dev Comp Immunol. 2009 Apr;33(4):547-58. Epub 2008 Nov 11.
DOI Direct Link |
→View more research publications. |
IFNA2 results (if any) from reagent suppliers | 
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IFNA2 protein, IFN ALPHA recombinant protein
Buy quality IFNA2 protein (n/a), IFNA2, IFN ALPHA recombinant protein, (fa n/a). RECOMBINANT CHICKEN INTERFERON ALPHA; Interferon alpha-2, IFNA2_HUMAN [ N/A ...
http://www.genwaybio.com/product_info.php?products_id=79387...
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POLYCLONAL ANTIBODY TO HUMAN GAMMA INTERFERON
Monoclonal antibody against Human IFN-alpha, clone IFNA2.3. HM2014. Monoclonal antibody against Human IFN-alpha, clone IFNA2.4.
http://www.hbt.nl/HP9019.pdf...
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PBL InterferonSource Human Interferon Alpha Antibody Specificity
The majority of human interferon alpha antibodies available today have been tested only against human IFN alpha A (IFNa2) and, less frequently, ...
http://www.interferonsource.com/New_InterferonSource/Antibod...
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IFN-α (5D4) Antibody sc-80996
Human, IFNA2, 3440, 9p21.3, P01563 · 147562. Human, IFNA2, 3440, 9p21.3, P01563 · 147562. Human, IFNA4, 3441, 9p21.3, P05014 ...
http://www.scbt.com/datasheet-80996-ifn-alpha-5d4-antibody.h...
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Carrier-Free Antibody and Reagent Products Catalog Number 34
... 34-8312 Carrier-Free Recombinant Mouse IFNa2 (Interferon-alpha 2, IFN-a2); 34-8313 Carrier-Free Recombinant Mouse IFNa4 (Interferon-alpha 4, IFN-a4) ...
http://www.ebioscience.com/ebioscience/sitemap/antibody_34.h...
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IFN Antibody / IFN Antibodies
IFN-α2b (CB-IFNA2.3) Antibody, sc-57223, mouse IgG1, FL (h), discontinued, human . IFN-α (4H124) Antibody, sc-71315, mouse IgG1, FL (h), discontinued, human ...
http://www.scbt.com/table-ifn.html...
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mouse IFNa antibody, Carrier-Free conjugate
34-8312, Carrier-Free Recombinant Mouse IFNa2 (Interferon-alpha 2, IFN-a2). 34- 8316, Carrier-Free Recombinant Human IFNa2 (Interferon-alpha 2, IFN-a2) ...
http://www.ebioscience.com/ebioscience/specs/antibody_34/34-...
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