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IGF1


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Gene DB Home
Symbol:IGF1
Name(s):insulin-like growth factor 1 (somatomedin C)
Type:protein-coding
Organism:Homo sapiens
Synonyms:IGFI
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17991453 Use of a strategy consisting of IGF-1 determination in blood is predictive of growth hormone deficiency.
18163429 Evidence for association between IGF-i single-nucleotide polymorphisms has been found.
18199734 Genetic variants in the IGF-I genes is not associated with breast cancer
18236213 Observational study of gene-disease association. (HuGE Navigator)
18237549 Observational study of gene-disease association. (HuGE Navigator)
18308828 Observational study of gene-disease association. (HuGE Navigator)
18316725 Observational study of gene-disease association. (HuGE Navigator)
18317720 Observational study of gene-disease association. (HuGE Navigator)
18349294 Observational study of gene-disease association. (HuGE Navigator)
17484040 IGF1-19/-19 genotype was significantly more common among BRCA1 mutation carriers (14.2%) than among non-carriers (4.8%)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDIGF-Iinsulin-like growth factor binding protein 5--Pubmed
HPRDIGF-Iimmunoglobulin superfamily, member 1--Pubmed
HPRDInsulin like growth factor Iimmunoglobulin superfamily, member 1--Pubmed
HPRDinsulin-like growth factor IB prepropeptideIGF binding protein 5--Pubmed
HPRDinsulin-like growth factor IB prepropeptideImmunoglobulin superfamily member 1--Pubmed
HPRDinsulin-like growth factor IB prepropeptideinsulin-like growth factor binding protein 1 precursor--Pubmed
HPRDinsulin-like growth factor IB prepropeptideinsulin-like growth factor binding protein 1 precursor--Pubmed
HPRDinsulin-like growth factor IB prepropeptideinsulin-like growth factor binding protein 2--Pubmed
HPRDinsulin-like growth factor IB prepropeptideinsulin-like growth factor binding protein 2--Pubmed
HPRDinsulin-like growth factor IB prepropeptideinsulin-like growth factor binding protein 3--Pubmed

Recent Publications on IGF1:

Pubmed Logo
Two Short Children Born Small for Gestational Age with Insulin-Like Growth Factor 1 Receptor Haploinsufficiency Illustrate the Heterogeneity of Its Phenotype.
Context: Small for gestational age (SGA)-born children comprise a...
30th October, 2009
Department of Pediatrics, Subdivision of Endocrinology, Erasmus Medical J Clin Endocrinol Metab. 2009 Oct 28.
DOI Direct Link
Insulin-like Growth Factors and Fish Reproduction.
Knowledge on fish reproduction is of high relevance for basic fish biology...
30th October, 2009
Biol Reprod. 2009 Oct 28.
DOI Direct Link
Functional relationships among intrafollicular insulin-like growth factor 1, circulatory gonadotropins, and development of the dominant follicle in mares.
The functional relationships among intrafollicular free insulin-like...
30th October, 2009
Eutheria Foundation, Cross Plains, WI, 53528, USA; Department of Anim Reprod Sci. 2009 Sep 30.
DOI Direct Link
Astrocytes Regulate the Expression of Insulin-Like Growth Factor 1 Receptor (IGF1-R) in Primary Cortical Neurons During In Vitro Senescence.
The role of insulin-like growth factor 1 (IGF1) pathway as regulator of...
29th October, 2009
Section of General Pathology, Department of Pathology, University of J Mol Neurosci. 2009 Oct 28.
DOI Direct Link
Common Genetic Variation in IGF1, IGFBP1, and IGFBP3 and Ovarian Cancer Risk.
IGF1 and its binding proteins foster cellular proliferation and inhibit...
28th October, 2009
Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Carcinogenesis. 2009 Oct 25.
DOI Direct Link

View more research publications.

Press Releases on IGF1:

BioPortfolio Logo
5-Year Study Published in Diabetologia Demonstrated Long-Term Safety of Lantus(R) Compared to NPH 6th July, 2009 sanofi-aventis

BRIDGEWATER, N.J., July 6 /PRNewswire-FirstCall/ -- Sanofi-aventis (EURONEXT: SAN and NYSE: SNY) announced today that the results of the long-term, 5-year study of Lantus(R)

Monogram Announces Issuance of Key Patents Related to VeraTag(TM) Technology 23rd July, 2008 Monogram Biosciences, Inc.

SOUTH SAN FRANCISCO, Calif., July 23 /PRNewswire-FirstCall/ -- Monogram Biosciences, Inc. (Nasdaq: MGRM) announced today that three key United States Patents for its proprietary VeraTag(TM)

BioNews Results for IGF1

: RSS Logo
BioPortfolio Logo
Suppression of Insulin-Like Growth Factor Acid-Labile Subunit (IGFALS) Expression - A Novel Mechanism for Deox
Toxicological Sciences:  Oct 6 2009 2:37PM Matching: igf1
Polymorphisms in the IGF1 signalling pathway including the myostatin gene are associated with left ventricular mass in male athletes [Original article]
British Journal of Sports Medicine:  Oct 1 2009 1:54AM Matching: igf1
NextBio Raises $8 Million For Life Sciences Search Engine
PaidContent.org:  Sep 18 2009 7:28PM Matching: igf1

Clinical Trials:

Clinical Trials Logo
Treatment of Children and Adolescents With Growth Failure Associated With Primary Insulin-Like Growth Factor-1 (IGF-1) Deficiency

Patents:

Patents logo
US Patent No.Title
7442525 Method for expressing HIV polypeptides
7511136 Aminoindazole derivatives active as kinase inhibitors
7514460 Benzazole analogues and uses thereof
7517863 Enhanced secretion/retention of growth hormone releasing hormone (GHRH) from muscle cells by species-specific signal peptide
7521211 IGF-1 and IGF-2 chimeric polypeptides and therapeutic uses thereof

View more patents.

IGF1 results (if any) from reagent suppliers

Google CSE Logo
The Abcam catalog
IGF1 antibodies. ... IGF1 antibody (Biotin). WB, ELISA, sELISA. Rabbit polyclonal ... IGF1 antibody (HRP). ELISA. Sheep polyclonal. HRP conjugated ...
http://www.abcam.com/index.html?t=815&pt=1&c=2218...

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IGF-I Antibody Anti-Human IGF-1
IGF-I antibody: Polyclonal rabbit antibody from ProSci Incorporated for research on growth factors,
http://www.prosci-inc.com/shop/catalog1/IGF-I-Antibody-p-191...

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IGF1 antibody (ab9860) | Abcam
Goat polyclonal to IGF1. Insulin is a pancreatic hormone that regulates glucose uptake and the synthesis of protein and fat. The insulin like growth factors ...
http://www.abcam.com/IGF1-antibody-ab9860.html...

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Anti-IGF1 Receptor Monoclonal Antibody
Monoclonal Antibody against IGF1 Receptor for use in Western Blot.
http://www.bioreagents.com/products/productDetails/productDe...

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IGF1 Receptor (phospho Y1161) antibody (ab39398) | Abcam
Rabbit polyclonal to IGF1 Receptor (phospho Y1161). There are two kinds of IGF receptors based on their relative affinities for IGF1 versus IGF2.
http://www.abcam.com/igf1-receptor-phospho-y1161-antibody-ab...

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Anti-IGF1 Receptor Monoclonal Antibody
Monoclonal Antibody against IGF1 Receptor for use in Immunoprecipitation.
http://www.bioreagents.com/products/productDetails/productDe...

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IGF1 Receptor (IGF1R) Antibody (C-term)
Abgent develops powerful tools to profile posttranslational modifications related to cellular function and disease. Abgent antibodies target protein
kinases ...
http://www.abgent.com/products/catalog_no/AP7649b_IGF1_Recep...

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