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APOE


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Gene DB Home
Symbol:APOE
Name(s):apolipoprotein E
Type:protein-coding
Organism:Homo sapiens
Synonyms:AD2, LPG, MGC1571, apoprotein
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18258839 Alzheimer's disease structural and biochemical arteriolar abnormalities did not vary as a function of APOE genotype.
17975753 To evaluate a possible association between the epsilon polymorphism of the apolipoprotein E gene (apo E) and premature IHD
18219091 The APOE epsilon2 allele was in linkage disequilibrium with the -427C allele in atherosclerosis diseases, and the -219T allele was associated with the epsilon4 allele in the ischemia heart disease group.
17938569 Observational study of gene-disease association. (HuGE Navigator)
18197377 Observational study of gene-disease association. (HuGE Navigator)
18198422 Observational study of genetic testing. (HuGE Navigator)
18201725 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18205760 Observational study of gene-disease association. (HuGE Navigator)
18210157 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18210273 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDalpha-2-macroglobulin precursorapolipoprotein E precursor--Pubmed
HPRDalpha-2-macroglobulin precursorapolipoprotein E precursor--Pubmed
HPRDalbumin precursorapolipoprotein E precursor--Pubmed
HPRDalbumin precursorapolipoprotein E precursor--Pubmed
HPRDApolipoprotein Elow density lipoprotein-related protein 1--Pubmed
HPRDApolipoprotein Elow density lipoprotein-related protein 2--Pubmed
HPRDapolipoprotein E precursorLow density lipoprotein receptor-related protein 1--Pubmed
HPRDapolipoprotein E precursorLow density lipoprotein related protein 2--Pubmed
HPRDapolipoprotein E precursoramyloid beta A4 protein precursor, isoform a--Pubmed
HPRDapolipoprotein E precursorlow density lipoprotein receptor precursor--Pubmed

Recent Publications on APOE:

Pubmed Logo
NADPH Oxidase Isoforms and Anti-hypertensive Effects of Atorvastatin Demonstrated in Two Animal Models.
Beneficial effects of statins on cardiovascular diseases have been...
3rd November, 2009
Department of Pharmacology, Kyoto Prefectural University of Medicine, J Pharmacol Sci. 2009 Oct 31.
Regulation of cellular immunity prevents Helicobacter pylori-induced atherosclerosis.
Helicobacter pylori (H. pylori) is a predominant pathogen that causes not...
3rd November, 2009
Department of Bacteriology, Okayama University Graduate School of Lupus. 2009 Nov;18(13):1154-68.
DOI Direct Link
Vascular wall ACE is not required for atherogenesis in ApoE(-/-) mice.
BACKGROUND: It has been proposed that elements of the renin angiotensin...
3rd November, 2009
Department of Medicine, Emory University School of Medicine, Atlanta, GA, Atherosclerosis. 2009 Oct 6.
DOI Direct Link
Salivary cortisol, APOE-varepsilon4 allele and cognitive decline in a prospective study of older persons.
OBJECTIVE: We determined whether salivary cortisol levels were associated...
3rd November, 2009
University Medical Center Utrecht, Julius Center for Health Sciences and Neurobiol Aging. 2009 Oct 29.
DOI Direct Link
Working memory deficits in healthy APOE epsilon 4 carriers.
Studies on the cognitive effects of APOE allele variation in healthy...
3rd November, 2009
Center for Study of Human Cognition, Department of Psychology, University Neuropsychologia. 2009 Oct 28.
DOI Direct Link

View more research publications.

BioNews Results for APOE

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Genetic Testing For Alzheimers Disease And Its Impact On Insurance Purchasing Behavior
Health Affairs:  Oct 13 2009 5:08PM Matching: apoe
Researchers Explore Diabetes, Gene and Cognitive Performance Relationship
PhysOrg.com:  Oct 2 2009 12:57AM Matching: apoe
Alzheimers disease beyond APOE
Nature Chemical Biology:  Sep 28 2009 7:09PM Matching: apoe
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
Nature Chemical Biology:  Sep 28 2009 7:10PM Matching: apoe
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
Nature Chemical Biology:  Sep 28 2009 7:10PM Matching: apoe
Promote your company here: BioNewsCast - Press Release Distribution

View more news.

Clinical Trials:

Clinical Trials Logo
The Impact of Lorazepam on Cognition in APOE e4 Carriers

Patents:

Patents logo
US Patent No.Title
7537758 Antibodies against a peptide epitope of apolipoprotein B
7560586 Acid and ester compounds and methods of using the same
7563572 Method for long range allele-specific PCR
7563617 Hybrid adenovirus/adeno-associated virus vectors and methods of use thereof
7563909 Statin derivatives

View more patents.

APOE results (if any) from reagent suppliers

Google CSE Logo
apoE (13F4B5) Antibody sc-130506
apoE shRNA (h) Lentiviral Particles, sc-29708-V, 200 µl ... apoE (13F4B5): sc- 130506. Western blot analysis of apoE expression in Hep G2 whole cell lysate.
...
http://www.scbt.com/datasheet-130506-apoe-13f4b5-antibody.ht...

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APOE antibody, Apo E Antibody, Goat Polyclonal Antibody
Buy quality goat APOE antibody (interacts with human), anti-APOE, Apo E antibody , goat polyclonal antibody, Apo E Antibody, Goat Polyclonal Antibody ...
http://www.genwaybio.com/product_info.php?products_id=81024...

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apoE (R-20) Antibody sc-6385
See how others have used apoE (R-20): sc-6385 antibody and or apoE (R-20) ... A role for LRP4 in neuronal cell viability is related to apoE-binding. ...
http://www.scbt.com/datasheet-6385-apoe-r-20-antibody.html...

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GeneTex Inc. - Your source for monoclonal, polyclonal, primary ...
ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein ... The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. ...
http://www.genetex.com/WebPage/Product/ProductDetail.aspx?Ca...

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apoE (M-20) Antibody sc-6384
See how others have used apoE (M-20): sc-6384 antibody and or apoE (M-20) antibody ... Fenofibrate reduces atherogenesis in ApoE*3Leiden mice: evidence
for ...
http://www.scbt.com/datasheet-6384-apoe-m-20-antibody.html...

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Apolipoprotein E/ApoE - R&D Systems
ApoE is a 34 kDa protein component of serum chylomicrons, VLDL, and HDL particles. It mediates the binding, uptake, and catabolism of these particles
...
http://www.rndsystems.com/molecule_detail.aspx?m=3686...

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apoE (WU E-4) Antibody sc-53570
mouse monoclonal IgG1, 200µg/ml; raised against ApoE of human origin ... apoE ( WU E-4): sc-53570. Western blot analysis of apoE expression in Hep G2 whole ...
http://www.scbt.com/datasheet-53570-apoe-wu-e-4-antibody.htm...

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