Recent Publications on : |  |
Sequence variation in IGF1R is associated with differences in insulin levels in nondiabetic Old Order Amish.
BACKGROUND: Insulin growth factor-1 receptor (IGF1R) encodes the...
Direct Link | 31st October, 2009
| Department of Epidemiology, Johns Hopkins Bloomberg School of Public
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Two Short Children Born Small for Gestational Age with Insulin-Like Growth Factor 1 Receptor Haploinsufficiency Illustrate the Heterogeneity of Its Phenotype.
Context: Small for gestational age (SGA)-born children comprise a...
Direct Link | 30th October, 2009
| Department of Pediatrics, Subdivision of Endocrinology, Erasmus Medical
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Frequent deletion of CDKN2A and recurrent coamplification of KIT, PDGFRA, and KDR in fibrosarcoma of bone-An array comparative genomic hybridization study.
Very little is known about the genetics of fibrosarcoma (FS) of bone. We...
Direct Link | 29th October, 2009
| Department of Pathology, Haartman Institute and HUSLAB, University of
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Insulin Receptor and IGF1R Are Not Required for Oocyte Growth, Differentiation, and Maturation in Mice.
In mammals, insulin and insulin-like growth factors (IGFs: IGF1 and IGF2)...
Direct Link | 24th October, 2009
| Department of Genetic Medicine and Development, University of Geneva
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Genetic variation in insulin-like growth factor signaling genes and breast cancer risk among BRCA1 and BRCA2 carriers.
ABSTRACT: INTRODUCTION: Women who carry mutations in BRCA1 and BRCA2 have...
Direct Link | 22nd October, 2009
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The type I insulin-like growth factor receptor regulates cancer metastasis independently of primary tumor growth by promoting invasion and survival.
The type I insulin-like growth factor receptor (IGF1R) regulates multiple...
Direct Link | 20th October, 2009
| [1] Department of Medicine, University of Minnesota, Minneapolis, MN, USA
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| Enhancement of AG1024-induced H9c2 cardiomyoblast cell apoptosis via the interaction of IGF2R with Galpha proteins and its downstream PKA and PLC-beta modulators by IGF-II.
| 17th October, 2009
| Institute of Biochemistry and Biotechnology, Chung Shan Medical
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IGF1 induces up-regulation of steroidogenic and apoptotic regulatory genes via activation of phosphatidylinositol-dependent kinase/AKT in bovine granulosa cells.
IGF1, a potent stimulator of cellular proliferation, differentiation and...
Direct Link | 13th October, 2009
| A Mani, Animal Biochemistry Division, National Dairy Research Institute,
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Expression of insulin receptor isoform A and insulin-like growth factor-1 receptor in human acute myelogenous leukemia: effect of the dual-receptor inhibitor BMS-536924 in vitro.
The insulin receptor (IR) and insulin-like growth factor-1 receptor...
Direct Link | 1st October, 2009
| Departments of Medicine and Oncology, Mayo Clinic College of Medicine,
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Insulin-like growth factor receptor 1 (IGF1R) expression and survival in surgically resected non-small-cell lung cancer (NSCLC) patients.
BACKGROUND: The purpose of this study is to investigate the prognostic...
Direct Link | 22nd September, 2009
| Department of Oncology-Hematology, Istituto Clinico Humanitas Istituto di
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Submicroscopic genomic alterations in Silver-Russell syndrome and Silver-Russell-like patients.
BACKGROUND: Silver-Russell syndrome (SRS, OMIM# 180860) features fetal and...
Direct Link | 16th September, 2009
| Karolinska Institutet, Sweden.
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Interaction of myocardial insulin receptor and IGF receptor signaling in exercise-induced cardiac hypertrophy.
Insulin-like growth factor-1 (IGF-1) signaling has recently been...
Direct Link | 12th September, 2009
| Department of Cardiovascular Science and Medicine, Chiba University
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Reversal of oncogene transformation and suppression of tumor growth by the novel IGF1R kinase inhibitor A-928605.
BACKGROUND: The insulin-like growth factor (IGF) axis is an important...
Direct Link | 8th September, 2009
| Cancer Research, Global Pharmaceutical Research and Development, Abbott
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MicroRNA-122 inhibits tumorigenic properties of hepatocellular carcinoma cells and sensitizes these cells to Sorafenib.
MicroRNAs are negative regulators of protein coding genes. The liver...
Direct Link | 4th September, 2009
| Howard Hughes Medical Institute, United States;
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| Differential roles of insulin-like growth factor receptor- and insulin receptor-mediated signaling in the phenotypes of hepatocellular carcinoma cells.
| 3rd September, 2009
| Program in Gene Function and Expression, University of Massachusetts
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