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IGFBP1


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Symbol:IGFBP1
Name(s):insulin-like growth factor binding protein 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:AFBP, IBP1, IGF-BP25, PP12, hIGFBP-1
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
16306374 Observational study of gene-disease association. (HuGE Navigator)
16404426 Observational study of gene-disease association. (HuGE Navigator)
17035411 Observational study of gene-disease association. (HuGE Navigator)
17164371 Observational study of gene-disease association. (HuGE Navigator)
17300730 Observational study of gene-disease association. (HuGE Navigator)
17566087 Observational study of gene-disease association. (HuGE Navigator)
17914103 Observational study of gene-disease association. (HuGE Navigator)
17972051 Observational study of gene-disease association. (HuGE Navigator)
17640761 Ethanol induced the IGFBP-1 mRNA and protein in hepatoma cells up to 5-fold in a dose-dependent manner. A similar effect was observed in cultured human hepatocytes.
17890489 plasma adiponectin has a role in regulating sex hormone and insulin-like growth factor levels, including SHBG, c-peptide, and IGFBP-1

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDinsulin-like growth factor IB prepropeptideinsulin-like growth factor binding protein 1 precursor--Pubmed
HPRDinsulin-like growth factor IB prepropeptideinsulin-like growth factor binding protein 1 precursor--Pubmed
BINDinsulin-like growth factor 1 isoform 4 preproproteininsulin-like growth factor binding protein 1 precursorIGF-I interacts with IGFBP-1.-Pubmed
HPRDIGF-IIinsulin-like growth factor binding protein 1 precursor--Pubmed
HPRDHuman preproinsulin-like growth factor II variant mRNA, and translated productsIGF binding protein 1--Pubmed
BINDinsulin-like growth factor 2insulin-like growth factor binding protein 1 precursorIGF-II interacts with IGFBP-1.-Pubmed
HPRDIGF binding protein 1transferrin--Pubmed
HPRDinsulin-like growth factor binding protein 1 precursorTransferrin--Pubmed

Recent Publications on IGFBP1:

Pubmed Logo
Hormonal and metabolic factors associated with variations in insulin sensitivity in human pregnancy.
Objective: To determine maternal hormonal and metabolic factors associated...
3rd November, 2009
The University of Queensland and Mater Health Services, South Brisbane, Diabetes Care. 2009 Oct 30.
DOI Direct Link
Interactions of thyroid hormones; insulin-like growth factor-1 (IGF-1), IGF binding proteins, and nutritional anthropometric parameters in school children with goiter detected by palpation.
AIM: In the present study we evaluated anthropometric indices, serum...
31st October, 2009
Division of Pediatric Endocrinology and Metabolism, Department of Exp Clin Endocrinol Diabetes. 2009 Oct;117(9):490-5. Epub 2009 Oct 29.
DOI Direct Link
Two Short Children Born Small for Gestational Age with Insulin-Like Growth Factor 1 Receptor Haploinsufficiency Illustrate the Heterogeneity of Its Phenotype.
Context: Small for gestational age (SGA)-born children comprise a...
30th October, 2009
Department of Pediatrics, Subdivision of Endocrinology, Erasmus Medical J Clin Endocrinol Metab. 2009 Oct 28.
DOI Direct Link
Common Genetic Variation in IGF1, IGFBP1, and IGFBP3 and Ovarian Cancer Risk.
IGF1 and its binding proteins foster cellular proliferation and inhibit...
28th October, 2009
Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Carcinogenesis. 2009 Oct 25.
DOI Direct Link
Amphetamine and environmentally induced hyperthermia differentially alter the expression of genes regulating vascular tone and angiogenesis in the meninges and associated vasculature.
An amphetamine (AMPH) regimen that does not produce a prominent...
27th October, 2009
US Food and Drug Administration, National Center for Toxicological Synapse. 2009 Oct;63(10):881-94.
DOI Direct Link

View more research publications.

BioNews Results for IGFBP1

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Genetic variation in insulin-like growth factor signaling genes and breast cancer risk among BRCA1 and BRCA2 carriers
MDLinx:  Oct 26 2009 10:36AM Matching: igfbp1

Clinical Trials:

Clinical Trials Logo
The Effect of Ethanol on Overnight Glucose Regulation in Type 2

Patents:

Patents logo
US Patent No.Title
7605185 Treatment of arrhythmia by retinoids affecting signal transduction
5994303 Use of insulin and IGF-I
5985830 Use of IGF-I for the treatment of kidney disorders
5902788 Insulin-like growth factor II as antitumour agent
5783559 Solution containing IGF-1

View more patents.

IGFBP1 results (if any) from reagent suppliers

Google CSE Logo
IGFBP1 antibody [3H2470] (ab13282) | Abcam
Mouse monoclonal [3H2470] to IGFBP1. Insulin like growth factor binding protein 1 (IGFBP1) is a member of the superfamily of insulin like growth factor ...
http://www.abcam.com/IGFBP1-antibody-3H2470-ab13282.html...

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IGFBP1 (M-19) Antibody sc-6000
See how others have used IGFBP1 (M-19): sc-6000 antibody and or IGFBP1 (M-19) ... Western blot analysis of IGFBP1 expression in non-transfected 293T: ...
http://www.scbt.com/datasheet-6000-igfbp1-m-19-antibody.html...

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Insulin-like growth factor binding protein-1 (IGFBP-1), antibody
HyTest Ltd. is a supplier of cardiac markers, human proteins, neuroscience, autoimmune and infectious disease reagents. troponin c-reactive protein Heat ...
http://www.hytest.fi/product/insulin-like-growth-factor-bind...

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IGFBP1 (H-3) Antibody sc-25257
IGFBP1 (H-3): sc-25257. Western blot analysis of human recombinant IGFBP1. ... Western blot analysis of IGFBP1 expression in HepG2 whole cell lysate. ...
http://www.scbt.com/datasheet-25257-igfbp1-h-3-antibody.html...

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Rabbit Anti-human IGFBP-1 Polyclonal Antibody for Immunohistochemistry
Characterized for the immunohistochemical detection of IGFBP-1 in paraffin embedded sections of embryonic rat tissues. A final dilution of 1:250 for IHC
...
http://www.cellsciences.com/PDF/PAAH1.pdf...

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Mouse IGFBP-1 MAb (Clone 176110)
IGFBP-1 is one of several proteins that bind IGF with high affinity ... This antibody was selected for its ability to detect mouse IGFBP-1 in direct ELISAs
...
http://www.rndsystems.com/pdf/mab1240.pdf...

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IGFBP Antibody / IGFBP Antibodies
IGFBP1 (33627.11) Antibody, sc-57230, mouse IgG1, FL (h), WB, ELISA, human ... IGFBP1 (G2) Antibody, sc-51999, mouse IgG2a, FL (h), WB, human ...
http://www.scbt.com/table-igfbp.html...

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