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IGFBP2
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18210030 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18210156 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18217408 |
IGFBP-2 may have a role in relapse of childhood acute lymphoblastic leukemia |
| 17985932 |
analyzed the molecular interactions among the N-domain of IGFBP-2 (N-BP-2), C-BP-2, and IGFs using cross-linking and nuclear magnetic resonance (NMR) spectroscopy |
| 17827400 |
Variations confer impaired glucose- and tolbutamide-induced insulin release in middle-aged and young healthy subjects. |
| 17970029 |
As well as other types of carcinomas, overexpression of IGFBP-2 has been reported in glioblastoma multiforme (GBM), the most malignant brain tumor characterized by rapid growth, extensive invasiveness, and angiogenesis. |
| 17655506 |
[(125)I]-labeled IGFBP-2 and -3, but not IGFBP-1, were proteolyzed by Ca(2+)-activated m-calpain in vitro. |
| 17369847 |
IGF-II and IGFBP-2 differentially regulate PTEN in human breast cancer cells |
| 17606927 |
IGFBP2 plays a key role in activation of the Akt pathway and collaborates with K-Ras in the development and progression of two major types of glioma. |
| 17341887 |
The results provide further evidence that IGFBP-2 and IGF-II in breast milk are relevant factors for the early development of preterm infants. | →View more information from publications. |
Recent Publications on IGFBP2: |  |
OBSL1 mutations in 3-M syndrome are associated with a modulation of IGFBP2 and IGFBP5 expression levels.
3-M syndrome is an autosomal recessive disorder characterized by severe... | 31st October, 2009
| University Paris Descartes, Department of Genetics and INSERM U781,
| Hum Mutat. 2009 Oct 29.
DOI Direct Link |
Common Genetic Variation in IGF1, IGFBP1, and IGFBP3 and Ovarian Cancer Risk.
IGF1 and its binding proteins foster cellular proliferation and inhibit... | 28th October, 2009
| Obstetrics and Gynecology Epidemiology Center, Brigham and Women's
| Carcinogenesis. 2009 Oct 25.
DOI Direct Link |
Genetic variation in insulin-like growth factor signaling genes and breast cancer risk among BRCA1 and BRCA2 carriers.
ABSTRACT: INTRODUCTION: Women who carry mutations in BRCA1 and BRCA2 have... | 22nd October, 2009
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| Breast Cancer Res. 2009 Oct 20;11(5):R76.
DOI Direct Link |
IGFBP2 is a candidate biomarker for Ink4a-Arf status and a therapeutic target for high-grade gliomas.
The levels of insulin-like growth factor-binding protein 2 (IGFBP2) are... | 7th October, 2009
| Departments of Pathology and Neurosurgery, University of Texas MD Anderson
| Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16675-9. Epub 2009 Sep 16.
DOI Direct Link |
Identification of five candidate lung cancer biomarkers by proteomic analysis of conditioned media of four lung cancer cell lines.
Detection of lung cancer at an early stage is necessary for successful... | 25th September, 2009
| Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario
| Mol Cell Proteomics. 2009 Sep 23.
DOI Direct Link |
→View more research publications. |
IGFBP2 results (if any) from reagent suppliers | 
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