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IGFBP3


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Gene DB Home
Symbol:IGFBP3
Name(s):insulin-like growth factor binding protein 3
Type:protein-coding
Organism:Homo sapiens
Synonyms:BP-53, IBP3
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18287864 Observational study of gene-disease association. (HuGE Navigator)
15894694 Observational study of gene-disease association. (HuGE Navigator)
15941947 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
15986122 Observational study of gene-disease association. (HuGE Navigator)
16030120 Observational study of gene-disease association. (HuGE Navigator)
16049980 Observational study of gene-disease association. (HuGE Navigator)
16215864 Observational study of gene-disease association. (HuGE Navigator)
16306136 Observational study of gene-disease association. (HuGE Navigator)
16404426 Observational study of gene-disease association. (HuGE Navigator)
16448675 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDprostate specific antigen isoform 1 preproproteininsulin-like growth factor binding protein 3--Pubmed
HPRDprostate specific antigen isoform 1 preproproteininsulin-like growth factor binding protein 3 isoform a precursor--Pubmed
HPRDCD44 antigeninsulin-like growth factor binding protein 3--Pubmed
HPRDCD44 antigeninsulin-like growth factor binding protein 3--Pubmed
HPRDCD44 antigen isoform 1 precursorinsulin-like growth factor binding protein 3 isoform a precursor--Pubmed
HPRDalpha 1 type I collagen preproproteininsulin-like growth factor binding protein 3--Pubmed
HPRDalpha 1 type I collagen preproproteininsulin-like growth factor binding protein 3--Pubmed
HPRDfibronectin 1 isoform 3 preproproteininsulin-like growth factor binding protein 3--Pubmed
HPRDfibronectin 1 isoform 3 preproproteininsulin-like growth factor binding protein 3--Pubmed
HPRDfibronectin 1 isoform 3 preproproteininsulin-like growth factor binding protein 3 isoform a precursor--Pubmed

Recent Publications on IGFBP3:

Pubmed Logo
Interactions of thyroid hormones; insulin-like growth factor-1 (IGF-1), IGF binding proteins, and nutritional anthropometric parameters in school children with goiter detected by palpation.
AIM: In the present study we evaluated anthropometric indices, serum...
31st October, 2009
Division of Pediatric Endocrinology and Metabolism, Department of Exp Clin Endocrinol Diabetes. 2009 Oct;117(9):490-5. Epub 2009 Oct 29.
DOI Direct Link
Common Genetic Variation in IGF1, IGFBP1, and IGFBP3 and Ovarian Cancer Risk.
IGF1 and its binding proteins foster cellular proliferation and inhibit...
28th October, 2009
Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Carcinogenesis. 2009 Oct 25.
DOI Direct Link
Maternal high-fat diet promotes body length increases and insulin insensitivity in second-generation mice.
Maternal obesity and diet consumption during pregnancy have been linked to...
13th October, 2009
University of Pennsylvania, Department of Animal Biology, 201E Vet, 6046, Endocrinology. 2009 Nov;150(11):4999-5009. Epub 2009 Oct 9.
DOI Direct Link
IGF1 and IGFBP3 polymorphisms and plasma levels in women.
Maternal obesity and diet consumption during pregnancy have been linked to...
10th October, 2009
Cancer Epidemiol Biomarkers Prev. 2009 Oct;18(10):2794; author reply 2795.
DOI Direct Link
Associations of insulin-like growth factor binding protein-3 gene polymorphisms with IGF-I activity and lipid parameters in adolescents.
Objective:Childhood obesity is a growing global epidemic. Recent studies...
30th September, 2009
[1] Department of Biochemistry, The Chinese University of Hong Kong, The Int J Obes (Lond). 2009 Sep 29.
DOI Direct Link

View more research publications.

Press Releases on IGFBP3:

BioPortfolio Logo
Insmed Gains Royalty-Free Worldwide Rights for IPLEX(TM) in Connection with Potential Expanded Access ALS Programs 10th November, 2008 Insmed Inc.

RICHMOND, Va., Nov. 10 /PRNewswire-FirstCall/ -- Insmed Inc. (Nasdaq: INSM), a developer of follow-on biologics and biopharmaceuticals, today announced that Genentech, Ipsen/Tercica and Insmed

Clinical Trials:

Clinical Trials Logo
The IGFBP-3 Stimulation Test: A New Tool for the Diagnosis of Growth Hormone Deficiency in Children.

Patents:

Patents logo
US Patent No.Title
6706867 DNA array sequence selection
7081340 Gene expression profiling in biopsied tumor tissues
7105167 Methods for treating clinical manifestations of GH/GF axis dysregulation by administration of an IGF-I variant
7166288 Use of insulin-like growth factor binding protein 3 (IGF-BP3) for inhibition of tumor growth
7192738 IGF binding proteins

View more patents.

IGFBP3 results (if any) from reagent suppliers

Google CSE Logo
IGFBP3 (H-98) Antibody sc-9028
See how others have used IGFBP3 (H-98): sc-9028 antibody and or IGFBP3 (H-98) antibody conjugates. ... Western blot analysis of human recombinant IGFBP3. ...
http://www.scbt.com/datasheet-9028-igfbp3-h-98-antibody.html...

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IGFBP3 antibody (ab4248) | Abcam
Rabbit polyclonal to IGFBP3. Insulin like growth factor binding protein 3 ( IGFBP3) is a member of the superfamily of insulin like growth factor (IGF) ...
http://www.abcam.com/IGFBP3-antibody-ab4248.html...

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IGFBP3 (C-19) Antibody sc-6003
IGFBP3 shRNA (h) Lentiviral Particles, sc-39587-V, 200 µl ... See how others have used IGFBP3 (C-19): sc-6003 antibody and or IGFBP3 (C-19) antibody ...
http://www.scbt.com/datasheet-6003-igfbp3-c-19-antibody.html...

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IGFBP3 Antibody IGFBP3
IGFBP3 antibody was raised against a synthetic peptide of IGFBP3.,
http://www.prosci-inc.com/shop/catalog1/IGFBP3-Antibody-p-27...

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IGFBP3 Antibody (S183)
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with IGFBP3 Antibody (S183) (Cat.#AP7641d), which was peroxidase-conjugated to ...
http://www.abgent.com/products/catalog_no/AP7641d_IGFBP3_Ant...

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IGFBP3 (4) Antibody sc-135947
Western blot analysis of IGFBP3 expression in human plasma . sc-135947. IGFBP3 ( 4): sc-135947. Immunofluorescence staining of human fibroblast cells. ...
http://www.scbt.com/datasheet-135947-igfbp3-4-antibody.html...

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IGFBP3 Antibody (N-term)
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with IGFBP3 Antibody (N-term) (Cat.#AP7641a), which was peroxidase-conjugated to ...
http://www.abgent.com/products/catalog_no/AP7641a_IGFBP3_Ant...

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