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IGFBP5
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18210156 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18085517 |
This suggests that IGFBP-5 possesses an IGF-independent suppressor function |
| 18161051 |
IGFBP-5 inducible by gankyrin overexpression may be involved human hepatocarcinogenesis. |
| 17892529 |
Insulin-like growth factor-binding protein-5 enters vesicular structures but not the nucleus |
| 17804819 |
IGFBP-5 plays a role in the regulation of cellular senescence via a p53-dependent pathway and in aging-associated vascular diseases |
| 17823924 |
Androgen suppressive therapy increases IGFBP5 in the bone marrow microenvironment and thereby may facilitate the progression of prostate cancer. |
| 17595320 |
IGFBP-5 can interact with VDR to prevent RXR:VDR heterodimerization; IGFBP-5 may attenuate the 1,25(OH)2D3-induced expression of bone differentiation markers. |
| 17651454 |
Overexpression of IGFBP5 was associated with breast cancer |
| 17496250 |
Phosphorylation and O-glycosylation both affected IGFBP-5 binding to heparin but not insulin-like growth factor binding or ternary complex formation with the acid-labile subunit. |
| 17067554 |
Inhibition of endogenously produced IGFBP-5 is associated with Bim-dependent apoptosis in NB cells. | →View more information from publications. |
Recent Publications on IGFBP5: |  |
OBSL1 mutations in 3-M syndrome are associated with a modulation of IGFBP2 and IGFBP5 expression levels.
3-M syndrome is an autosomal recessive disorder characterized by severe... | 31st October, 2009
| University Paris Descartes, Department of Genetics and INSERM U781,
| Hum Mutat. 2009 Oct 29.
DOI Direct Link |
Genetic variation in insulin-like growth factor signaling genes and breast cancer risk among BRCA1 and BRCA2 carriers.
ABSTRACT: INTRODUCTION: Women who carry mutations in BRCA1 and BRCA2 have... | 22nd October, 2009
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| Breast Cancer Res. 2009 Oct 20;11(5):R76.
DOI Direct Link |
FOS proliferating network construction in early colorectal cancer (CRC) based on integrative significant function cluster and inferring analysis.
The aim is to setup single distinguished molecular network. We constructed... | 18th September, 2009
| Center for Biomedical Engineering, Beijing University of Posts and
| Cancer Invest. 2009 Oct;27(8):816-24.
DOI Direct Link |
Association of sequence variations in the gene encoding insulin-like growth factor binding protein 5 with adiponectin.
BACKGROUND: Insulin-like growth factor binding protein 5 (IGFBP5) binds to... | 17th September, 2009
| Department of Clinical Nutrition, Food and Health Research Centre, School
| Int J Obes (Lond). 2009 Jan;33(1):80-8. Epub 2008 Oct 28.
DOI Direct Link |
IGF-independent effects of insulin-like growth factor binding protein-5 (Igfbp5) in vivo.
IGF activity is regulated tightly by a family of IGF binding proteins... | 19th August, 2009
| Laboratory of Molecular Signalling, The Babraham Institute, Cambridge CB22
| FASEB J. 2009 Aug;23(8):2616-26. Epub 2009 Mar 30.
DOI Direct Link |
→View more research publications. |
IGFBP5 results (if any) from reagent suppliers | 
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