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CycE
| Symbol: | CycE | | Name(s): | Cyclin E | | Type: | protein-coding | | Organism: | Drosophila melanogaster | | Synonyms: | BG:DS07108.3, CDI7, CG3938, Cyc E, CyclE, CyeE, D-CycE, DmCycE, DmcyclinE, br37, cyclinE, fond, l(2)05206, l(2)35Dd, l(2)br37, l(2)k02514, l(2)k02602, l(2)k05007, l35Dd, unnamed | | Links: |
Pubmed,
Entrez Gene,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 12015606 |
Hedgehog regulates cell growth and proliferation by inducing Cyclin D and Cyclin E. |
| 15355790 |
string(cdc25) and cyclin E control patterned histone expression at different stages of Drosophila embryonic development. |
| 15829522 |
Cell cycle diversity involves differential regulation of Cyclin E activity in the Drosophila bristle cell lineage. |
| 15342466 |
phosphorylation and degradation of Dup protein at G1/S requires cyclin E/CDK2 |
| 15580266 |
critical role for CycE in regulating cell fate in segment-specific neural lineages. |
| 12730292 |
centrosome overduplication still occurs in skpA-; cycE- mutant animals, demonstrating that high cyclin E levels are not necessary for centrosome overduplication |
| 16637514 |
The most significant cyclin E alteration is post-translational cleavage of full-length cyclin E into low molecular weight forms that are hyperactive compared to the 50-kDa, full-length protein and correlate with increasing stage of breast cancer. |
| 14973280 |
asymmetric divisions are due to upregulation of Cyclin E in late ganglion mother cells |
| 12093739 |
Brm complex mutants suppress the DmcycE(JP) phenotype by increasing S phases w/o affecting DmcycE protein levels. DmcycE physically interacts with Brm & Snr1 in vivo. The Brm complex inhibits S phase by acting downstream of DmcycE protein accumulation. |
| 16690050 |
Fondue is a major hemolymph protein required for efficient clotting in Drosophila | →View more information from publications. |
CycE results (if any) from reagent suppliers | 
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