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CycE
| Symbol: | CycE | | Name(s): | Cyclin E | | Type: | protein-coding | | Organism: | Drosophila melanogaster | | Synonyms: | BG:DS07108.3, CDI7, CG3938, Cyc E, CyclE, CyeE, D-CycE, DmCycE, DmcyclinE, br37, cyclinE, fond, l(2)05206, l(2)35Dd, l(2)br37, l(2)k02514, l(2)k02602, l(2)k05007, l35Dd, unnamed | | Links: |
Pubmed,
Entrez Gene,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 12015606 |
Hedgehog regulates cell growth and proliferation by inducing Cyclin D and Cyclin E. |
| 15355790 |
string(cdc25) and cyclin E control patterned histone expression at different stages of Drosophila embryonic development. |
| 15829522 |
Cell cycle diversity involves differential regulation of Cyclin E activity in the Drosophila bristle cell lineage. |
| 15342466 |
phosphorylation and degradation of Dup protein at G1/S requires cyclin E/CDK2 |
| 15580266 |
critical role for CycE in regulating cell fate in segment-specific neural lineages. |
| 12730292 |
centrosome overduplication still occurs in skpA-; cycE- mutant animals, demonstrating that high cyclin E levels are not necessary for centrosome overduplication |
| 16637514 |
The most significant cyclin E alteration is post-translational cleavage of full-length cyclin E into low molecular weight forms that are hyperactive compared to the 50-kDa, full-length protein and correlate with increasing stage of breast cancer. |
| 14973280 |
asymmetric divisions are due to upregulation of Cyclin E in late ganglion mother cells |
| 12093739 |
Brm complex mutants suppress the DmcycE(JP) phenotype by increasing S phases w/o affecting DmcycE protein levels. DmcycE physically interacts with Brm & Snr1 in vivo. The Brm complex inhibits S phase by acting downstream of DmcycE protein accumulation. |
| 16690050 |
Fondue is a major hemolymph protein required for efficient clotting in Drosophila | →View more information from publications. |
CycE results (if any) from reagent suppliers | 
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CDK1/CycE
confirmed as CDK1/CycE by specific Western. Blotting using anti CDK1 and CycE antibodies ... Recombinant CDK1/CycE: 200 ng / 50 µl. • Filter binding assay ...
http://www.cellsignal.com/pdf/7468.pdf...
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Using AlphaScreen to Detect GST-Protein Substrate Phosphorylation
A S/B value of 3.5 can be obtained using 1.2 nM (1.4 ng) of CDK3/CycE. .... CDK3 /CycE, 6 M ATP and 250 nM GST-Rb. A) Inhibition of CDK3 activity by generic ...
https://las.perkinelmer.com/Content/RelatedMaterials/Posters...
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CDK2/CycE Kinase #7524
Product Pathways - Cell Cycle / Checkpoint. CDK2/CycE Kinase #7524. pathway; more info; application references; datasheet PDF · MSDS PDF · protocols ...
http://www.cellsignal.com/products/7524.html...
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LANCE Ultra ERK1 Assay
CDK3/CycE. • POTENTIAL SUBSTRATE FOR KINASES: s6K, p43, p38. LANCE Ultra ERK1 Assay. Using ULight-Myelin Basic Protein (MBP) Peptide ...
http://las.perkinelmer.com/content/TechnicalInfo/TCH_LANCEUl...
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Datasheet: CDK2/CycE Description: Human CDK2 Full Length c-DNA ...
Recombinant CDK2/CycE: 100 ng / 50 µl. Assay: MAFC (Millipore) filter assay ... GST-CycE. 1. 1. 1: SP009, 500 ng. 1: SP009, 500 ng anti-CycE. GST-. CycE ...
http://www.cellsignal.com/pdf/7524.pdf...
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Bright Ideas: Highlights of Innovative Journal Articles Stem Cell ...
An increase in Cyclin E (CycE) expression was also observed, suggesting that Dicer-1–deficient. GSCs are arrested in the G1 to S transition. ...
http://www.invitrogen.com/etc/medialib/en/filelibrary/pdf/bi...
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Phospho-p57 Kip2 (Thr310) Antibody
CDK2/CycE Kinase #7524. Background References: (1) Lloyd, R.V. et al. (1999) Am. J. Pathol. 154, 313–323. (2) Polyak, K. et al. (1994) Genes Dev. 8, 9–22. ...
http://www.cellsignal.com/pdf/2558.pdf...
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