Gene Information from Publications |
| Publication Link |
Summary of findings |
| 12015606 |
Hedgehog regulates cell growth and proliferation by inducing Cyclin D and Cyclin E. |
| 15355790 |
string(cdc25) and cyclin E control patterned histone expression at different stages of Drosophila embryonic development. |
| 15829522 |
Cell cycle diversity involves differential regulation of Cyclin E activity in the Drosophila bristle cell lineage. |
| 15342466 |
phosphorylation and degradation of Dup protein at G1/S requires cyclin E/CDK2 |
| 15580266 |
critical role for CycE in regulating cell fate in segment-specific neural lineages. |
| 12730292 |
centrosome overduplication still occurs in skpA-; cycE- mutant animals, demonstrating that high cyclin E levels are not necessary for centrosome overduplication |
| 16637514 |
The most significant cyclin E alteration is post-translational cleavage of full-length cyclin E into low molecular weight forms that are hyperactive compared to the 50-kDa, full-length protein and correlate with increasing stage of breast cancer. |
| 14973280 |
asymmetric divisions are due to upregulation of Cyclin E in late ganglion mother cells |
| 12093739 |
Brm complex mutants suppress the DmcycE(JP) phenotype by increasing S phases w/o affecting DmcycE protein levels. DmcycE physically interacts with Brm & Snr1 in vivo. The Brm complex inhibits S phase by acting downstream of DmcycE protein accumulation. |
| 16690050 |
Fondue is a major hemolymph protein required for efficient clotting in Drosophila |
| 15632940 |
cyclin E functions downstream of the homeotic genes largly independently of its role in proliferation |
| 12737805 |
we link the CSN to the degradation of Cyclin E, which promotes the G1-S transition in the cell cycle and then is rapidly degraded by the ubiquitin-proteasome pathway |
