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EcR
| Symbol: | EcR | | Name(s): | Ecdysone receptor | | Type: | protein-coding | | Organism: | Drosophila melanogaster | | Synonyms: | CG1765, CG8347, DEcR, Dhr23, DmEcR, EcR-A, EcR-B, EcR-B1, EcRB-1, EcRB1, EcdR, NR1H1, anon-WO0229075.1, lie, ms(2)06410, ms(2)42A, snt | | Links: |
Pubmed,
Entrez Gene,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17884338 |
Indicate that the architecture of the E-domain of EcR is important for nuclear localization even in the absence of a ligand. |
| 17570142 |
results indicate that EcR and Usp can enter the nucleus independently, but cotransport of both receptors mediated by dimerization via the ligand binding domains is possible even in the absence of hormone |
| 17570491 |
data confirm that EcR and Usp can enter the nucleus independently and that intracellular localization is regulated individually for each receptor |
| 17238001 |
Deficiency of the ecdysone receptor system may have a role in courtship initiation by adult male fruit flies. |
| 12084064 |
ecdysteroids are capable of inducing heterodimer formation between EcR and USP |
| 12610309 |
flies that are heterozygous for mutations of the ecdysone receptor exhibit increases in life-span and resistance to various stresses, with no apparent deficit in fertility or activity |
| 17201771 |
This study revealed that the ecdysone receptor (EcR/USP) Ultraspiracle heterodimer displays isoform-specific capabilities. |
| 13677482 |
QSAR and CoMFA models for binding of a training set of 66 ecdysteroids and 97 diacylhydrazines to the D. melanogaster ecdysone receptor demonstrate the relative binding orientation of the two ligand families. |
| 14594447 |
Analysis of the role of ligand-binding domains in the heterodimerization of ecdysone receptor and ultraspiracle protein. |
| 12175493 |
epidermal Ddc induction at pupariation is under the control of an extended genomic region that contains both positive and negative regulatory elements | →View more information from publications. |
EcR results (if any) from reagent suppliers |
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