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EcR


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Symbol:EcR
Name(s):Ecdysone receptor
Type:protein-coding
Organism:Drosophila melanogaster
Synonyms:CG1765, CG8347, DEcR, Dhr23, DmEcR, EcR-A, EcR-B, EcR-B1, EcRB-1, EcRB1, EcdR, NR1H1, anon-WO0229075.1, lie, ms(2)06410, ms(2)42A, snt
Links: Pubmed, Entrez Gene, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17884338 Indicate that the architecture of the E-domain of EcR is important for nuclear localization even in the absence of a ligand.
17570142 results indicate that EcR and Usp can enter the nucleus independently, but cotransport of both receptors mediated by dimerization via the ligand binding domains is possible even in the absence of hormone
17570491 data confirm that EcR and Usp can enter the nucleus independently and that intracellular localization is regulated individually for each receptor
17238001 Deficiency of the ecdysone receptor system may have a role in courtship initiation by adult male fruit flies.
12084064 ecdysteroids are capable of inducing heterodimer formation between EcR and USP
12610309 flies that are heterozygous for mutations of the ecdysone receptor exhibit increases in life-span and resistance to various stresses, with no apparent deficit in fertility or activity
17201771 This study revealed that the ecdysone receptor (EcR/USP) Ultraspiracle heterodimer displays isoform-specific capabilities.
13677482 QSAR and CoMFA models for binding of a training set of 66 ecdysteroids and 97 diacylhydrazines to the D. melanogaster ecdysone receptor demonstrate the relative binding orientation of the two ligand families.
14594447 Analysis of the role of ligand-binding domains in the heterodimerization of ecdysone receptor and ultraspiracle protein.
12175493 epidermal Ddc induction at pupariation is under the control of an extended genomic region that contains both positive and negative regulatory elements

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
BINDultraspiracle CG4380-PA [Drosophila melanogaster].Ecdysone receptor CG1765-PB, isoform B [Drosophila melanogaster].USP interacts with EcR (EcR-B1).-Pubmed

EcR results (if any) from reagent suppliers

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ATCC: Catalog Search
293 EcR Shh cells carry a stably integrated construct for the expression of murine Sonic ... 293 EcR Shh cells can therefore be used for the production of
...
http://www.atcc.org/ATCCAdvancedCatalogSearch/ProductDetails...

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AnalytixLabInfo
AQUANAL®-professional Vario H Aluminium ECR Masking Reagenzien,. Nachfüllpackung für 70436. 23801-23. Chlor, freies. 0,01-2 mg/L ...
http://www.sigmaaldrich.com/etc/medialib/docs/Aldrich/Genera...

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RheoSwitch® Mammalian Inducible Expression System(E3000 ...
The RheoReceptor-1 protein is a highly engineered ligand-binding domain (LBD) of an insect EcR nuclear receptor fused to the yeast GAL4 DNA binding domain. ...
http://www.neb.com/nebecomm/products/productE3000.asp...

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AnalytixLabInfo
AQUANALо-professional Vario H Aluminium ECR Masking Reagent, refill pack for Cat . No. 70436. 23801-23. Chlorine, free. 0.01-2 mg / L Cl2 ...
http://www.sigmaaldrich.com/etc/medialib/docs/Aldrich/Genera...

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Dry Etch Process Application Note
Electron Cyclotron Resonance (ECR) tool –. This system uses a low-pressure, high -density ... of ECR tools is the magnetic field induced ...
http://www.pall.com/microe_38439.asp...

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Expressions 7.1
fected into EcR-293 cells (HEK-293 cells that sta- bly express the ecdysone receptor from the ... System and the EcR-293/hAE1 cell line will be ...
http://www.invitrogen.com/etc/medialib/en/filelibrary/pdf/ex...

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manual RheoSwitch Mammalian Inducible Expression System E3000S
ing domain (LBD) of an insect EcR nuclear receptor fused to the yeast GAL4 DNA binding domain. The RheoActivator protein is an insect/mammalian RXR hybrid ...
http://www.neb.com/nebecomm/ManualFiles/manualE3000.pdf...

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