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IL1RN


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Symbol:IL1RN
Name(s):interleukin 1 receptor antagonist
Type:protein-coding
Organism:Homo sapiens
Synonyms:ICIL-1RA, IL-1ra3, IL1F3, IL1RA, IRAP, MGC10430
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18239554 Observational study of gene-disease association. (HuGE Navigator)
18271063 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18278133 Observational study of gene-disease association. (HuGE Navigator)
18288454 Observational study of gene-disease association. (HuGE Navigator)
18299273 Observational study of gene-disease association. (HuGE Navigator)
18321309 Observational study of gene-disease association. (HuGE Navigator)
18322311 Observational study of gene-disease association. (HuGE Navigator)
18332090 Observational study of gene-disease association. (HuGE Navigator)
18333945 Observational study of gene-disease association. (HuGE Navigator)
18354254 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDnuclear receptor subfamily 3, group C, member 1 isoform alphainterleukin 1 receptor antagonist isoform 3--Pubmed
HPRDinterleukin 1 receptor, type I precursorinterleukin 1 receptor antagonist isoform 3--Pubmed
HPRDinterleukin 1 receptor, type I precursorinterleukin 1 receptor antagonist isoform 3--Pubmed
HPRDInterleukin 1 receptor antagonisttankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase--Pubmed
HPRDinterleukin 1 receptor antagonist isoform 3Tankyrase 1--Pubmed
HPRDinterleukin 1 receptor antagonist isoform 3interleukin 1 receptor, type II precursor--Pubmed
HPRDinterleukin 1 receptor antagonist isoform 3interleukin 1 receptor, type II precursor--Pubmed

Recent Publications on IL1RN:

Pubmed Logo
Mutations in the IL1RN locus lead to autoinflammation.
AIM: Since inflammation is an important contributor to atherosclerosis,...
30th October, 2009
Nat Rev Rheumatol. 2009 Sep;5(9):480-2.
DOI Direct Link
[Genetic evaluation of inflammation reaction and coronary disease]
OBJECTIVE: To discern the mode of interleukin-1 (IL-1) inhibition of...
29th October, 2009
Kardiol Pol. 2009 Jun;67(6):611-2.
Clinical relevance of nine transcriptional molecular markers for the diagnosis of head and neck squamous cell carcinoma in tissue and saliva rinse.
BACKGROUND: Analysis of 23 published transcriptome studies allowed us to...
20th October, 2009
Service d'ORL et Chirurgie Maxillo-faciale, Centre Hospitalier BMC Cancer. 2009 Oct 18;9:370.
DOI Direct Link
Interleukin-1 receptor antagonist gene (IL1RN) polymorphism possibly associated to severity of rheumatic carditis in a Brazilian cohort.
Aims: To evaluate the IL1RN polymorphism as a possible marker for...
14th October, 2009
Rheumatology Division, Faculdade de Medicina da Universidade de Sao Paulo, Cytokine. 2009 Oct 10.
DOI Direct Link
A novel exonic variant (221delT) in the LGALS13 gene encoding placental protein 13 (PP13) is associated with preterm labour in a low risk population.
Predicting adverse pregnancy outcome in low risk patients in a community...
13th October, 2009
Department of Obstetrics and Gynaecology, Paarl Hospital and University of J Reprod Immunol. 2009 Oct 7.
DOI Direct Link

View more research publications.

BioNews Results for IL1RN

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BioPortfolio Logo
Clinical relevance of nine transcriptional molecular markers for the diagnosis of head and neck squamous cell carcinoma in tissue and saliva rinse
MDLinx:  Oct 20 2009 9:27AM Matching: il1rn

Clinical Trials:

Clinical Trials Logo
Topical IL-1-Ra for Treatment of Posterior Blepharitis

Patents:

Patents logo
US Patent No.Title
7612181 Dual variable domain immunoglobulin and uses thereof
7208313 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector
6964850 Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles
6960439 Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles
6955901 Multiplex ligatable probe amplification

View more patents.

IL1RN results (if any) from reagent suppliers

Google CSE Logo
IL-1ra (H-110) Antibody sc-25444
Human, IL1RN, 3557, 2q13, NM_000577, NM_173841, NM_173842, NM_173843 · P18510 · 147679. Mouse, Il1rn, 16181, 2 A3, P25085 ...
http://www.scbt.com/datasheet-25444-il-1ra-h-110-antibody.ht...

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Abgent - Cancer Antibodies - Cancer
AT2513aNEW, IL1RN monoclonal antibody (M01), ELISA,S-ELISA,WB-Re, H. AT2522aNEW, IL6R monoclonal antibody (M01), ELISA,S-ELISA,WB-Re, H ...
http://www.abgent.com/products/category/cell_function/cancer...

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Biotin Anti-human IL-1 RA Antibody Anti-IL-1 - BioLegend
Other Names: Interleukin-1 receptor antagonist, IL-1 inhibitor, IL-1 receptor antagonist protein (IRAP), IL-1 inhibitory activity, ILS, MG50, IL-1RN, ...
http://www.biolegend.com/biotin-anti-human-il-1-ra-antibody-...

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IL-1ra (M-20) Antibody sc-8482
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIMâ„¢ Number. Mouse, Il1rn, 16181, 2 A3, P25085 ...
http://www.scbt.com/datasheet-8482-il-1ra-m-20-antibody.html...

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Recombinant Human Interleukin-1 receptor antagonist (IL-1ra) | Imgenex
Interleukin-1 receptor antagonist protein precursor (IL-1ra) (IRAP) (IL1 inhibitor) (IL-1RN) (ICIL-1RA). Protein Family. Belongs to the IL-1 family. ...
http://www.imgenex.com/recomb_tds.php?id=1061...

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IL-1ra (N-19) Antibody sc-8479
... Isoform (mRNA) Accession #, Protein Accession #, OMIMâ„¢ Number. Human, IL1RN, 3557, 2q13, NM_000577, NM_173841, NM_173842, NM_173843 · P18510 ...
http://www.scbt.com/datasheet-8479-il-1ra-n-19-antibody.html...

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