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INDO


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Symbol:INDO
Name(s):indoleamine-pyrrole 2,3 dioxygenase
Type:protein-coding
Organism:Homo sapiens
Synonyms:CD107B, IDO
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17951526 indoleamine 2,3-dioxygenase and prostaglandin E2 represent key mediators of the Mesenchymal stem cells-induced inhibition of NK cells
18036645 The present study has demonstrated for the first time that baseline IDO enzymatic activity in induced sputum from asthmatic patients is very low compared with that seen in nonasthmatic control subjects and is inversely related to sputum eosinophilia.
18055547 Type I IFN-mediated skin disorders, such as lichen planus , strongly express IDO in lesional skin.
18176870 We submit that an impaired IDO induction characterizes PBC (primary biliary cirrhosis)and might represent a contributing factor in disease pathogenesis in association with several specific defects in the target tissue
17911610 Interferon gamma-inducible expression of indoleamine 2,3-dioxygenase by human vascular smooth muscle cells inhibits allogeneic T cell activation, proliferation, and accumulation in vitro and in vivo.
17711549 Transfected into rats, reduces vascular permeability and leukocyte extravasation, and consequently improves graft function and histologic appearance.
17626075 poly(I:C)induction of IDO was mediated in part by IFN-beta but not IFN-gamma, and both NF-kappaB and interferon regulatory factor 3 (IRF3) were required.
17535808 NO inhibits rhIDO activity reversibly by binding to the active site heme to trap the enzyme as an inactive nitrosyl-Fe(II) enzyme adduct with Trp bound and O2 displaced
17170728 Acute myelocytic leukemia cells expresse INDO mRNA, but not IDO protein when exposed to optimal concentrations of IFN-gamma.
17674321 The levels of intralesional expression of mRNA of tumor necrosis factor-alpha, interferon, interleukin-10, RANTES, and indoleamine-2,3-dioxygenase in Mediterranean spotted fever are reported; levels of inducible nitric oxide synthase are also reported.

View more information from publications.

Recent Publications on INDO:

Pubmed Logo
[Change in concentration of cytosolic Ca2+ caused by extracellular ATP and ectoatpase activity in thymocytes and transformed MT-4 cells]
The comparative study of extracellular ATP (ATP0) effect on free cytosolic...
31st October, 2009
Ukr Biokhim Zh. 2009 Mar-Apr;81(2):27-33.
Functional balance training in collegiate women athletes.
This study examined the effects of functional balance training implemented...
27th October, 2009
Department of Health, Kinesiology, Recreation, and Dance, Graduate J Strength Cond Res. 2009 Oct;23(7):2124-9.
DOI Direct Link
Fine-scale analysis of synchronous breathing in wild Indo-Pacific bottlenose dolphins (Tursiops aduncus).
We quantitatively analysed synchronous breathing for dyads in Indo-Pacific...
24th October, 2009
Life Science Network, The University of Tokyo, 3-8-1 Komaba, Meguro-ku, Behav Processes. 2009 Oct 20.
DOI Direct Link
Prophylactic Indomethacin in Extremely Premature Infants between 23 and 24 Wks of Gestation.
Abstract Background: In extremely premature infants, the presence of a...
22nd October, 2009
Department of Neonatology, Hyogo Prefectural Kobe Children's Hospital Pediatr Int. 2009 Oct 14.
DOI Direct Link
Orchidectomy enhances the phenylephrine effects in isolated rat portal vein.
Summary 1) Orchidectomy produces a long-term testosterone deprivation...
22nd October, 2009
Laboratory of Pharmacology, Faculty of Medicine of Marilia, Sao Paulo, Clin Exp Pharmacol Physiol. 2009 Oct 16.
DOI Direct Link

View more research publications.

BioNews Results for INDO

: RSS Logo
BioPortfolio Logo
California Academy of Sciences becomes first aquarium in US to breed dwarf cuttlefish
Genetic Engineering News:  Nov 12 2009 8:25PM Matching: indo
Stem cell can treat blood cancers: Japanese scientist
DNA India:  Nov 9 2009 7:17AM Matching: indo
Stem cell can treat blood cancers: Japanese scientist
Livemint.com:  Nov 9 2009 6:45AM Matching: indo
Stem cells can treat blood cancers: Japanese scientist
Yahoo! India:  Nov 9 2009 5:08AM Matching: indo
Stem cells can treat blood cancers: Japanese
Yahoo! India:  Nov 9 2009 4:47AM Matching: indo
Promote your company here: BioNewsCast - Press Release Distribution

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Clinical Trials:

Clinical Trials Logo
An Escalating Dose Indomethacin for the Treatment of Persistent Patent Ductus Arteriosus (PDA) In Preterm Infants

Patents:

Patents logo
US Patent No.Title
7572245 Application of a therapeutic substance to a tissue location using an expandable medical device
7585643 Method for detecting kinase activity with thiol reactive fluorescent reagents
7585671 Hedgehog interacting proteins and uses related thereto
7585833 Malodor covering perfumery
7585931 Optically active high-molecular compounds

View more patents.

INDO results (if any) from reagent suppliers

Google CSE Logo
Indo-1, AM Calcium Sensor Dye
eBioscience technical data sheet for product 65-0856 Indo-1, AM Calcium Sensor Dye antibody.
http://www.ebioscience.com/ebioscience/specs/antibody_65/65-...

Thumbshot
Response of fura-2 and indo-1 to some divalent cations other than ...
Response of fura-2 and indo-1 to some divalent cations other than Ca{2+} and Mg{ 2+} - Table 19.5.
http://www.invitrogen.com/site/us/en/home/References/Molecul...

Thumbshot
INDO-1 AM (Ultra Pure) - Enzo Life Sciences
INDO1 AM Ultra Pure,CELLestial™ Fluorescent Probes and Labelling Products • Calcium Indicators / Probes,Signal Transduction,Calcium Chelators / Caged ...
http://www.enzolifesciences.com/ENZ-52008/indo-1-am-ultra-pu...

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INDO 1/AM sc-202181
After crossing the cell membrane, INDO 1/AM is rapidly hydrolyzed by cytoplasmic esterases and remains trapped within the cell. Can be used to selectively ...
http://www.scbt.com/datasheet-202181.html...

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Indo-1, pentapotassium salt
Fluorescent Dyes , Fluorescent Physiological and Neurological Indicators , Indo- 1, pentapotassium salt; Emission-ratiometric fluorescent Ca2+ indicator, ...
http://www.anaspec.com/products/product.asp?id=29706...

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INDO 1 pentapotassium salt sc-202661
INDO 1 pentapotassium salt sc-202661 INDO 1 pentapotassium salt sc-202661. ... INDO 1 pentapotassium salt. Click on image to enlarge. sc-202661. Download ...
http://www.scbt.com/datasheet-202661.html...

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Indo-1, AM
Fluorescent Dyes , Fluorescent Physiological and Neurological Indicators , Indo- 1, AM; Emission-ratiometric fluorescent indicator for quantifying ...
http://www.anaspec.com/products/product.asp?id=29701...

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