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MCPH1


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Gene DB Home
Symbol:MCPH1
Name(s):Microcephalin
Type:protein-coding
Organism:Drosophila melanogaster
Synonyms:CG13184, CG8981
Links: Pubmed, Entrez Gene, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17895362 model proposed in which MCPH1 coordinates the S-M transition in fly embryos: in the absence of mcph1, premature chromosome condensation results in mitotic entry with unreplicated DNA, genomic instability, and Chk2-mediated mitotic arrest
17895363 study reports that Drosophila MCPH1 is cyclically localised during the cell cycle, co-localising with DNA during interphase, but not with mitotic chromosomes

MCPH1 results (if any) from reagent suppliers

Google CSE Logo
MB-MN
WH0079648M7, Monoclonal Anti-MCPH1 antibody produced in mouse, 5C9 (monoclonal), purified immunoglobulin, human ... MCPH1(79648) ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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BRIT1 antibody (ab2612) | Abcam
It may play a role in neurogenesis and regulation of the size of the cerebral cortex. Defects in BRIT1 are the cause of primary microcephaly 1 (MCPH1) ...
http://www.abcam.com/BRIT1-antibody-ab2612.html...

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Microcephalin (N-15) Antibody sc-48882
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, MCPH1, 79648, 8p23.1, NM_024596 ...
http://www.scbt.com/ko/datasheet-48882-microcephalin-n-15-an...

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Microcephalin-1/BRIT1 (D38G5) XP™ Rabbit mAb #4120
Microcephalin-1 (MCPH1)/BRIT1 is an early DNA damage response protein named for its mutated state in the human disease primary microcephaly. ...
http://www.cellsignal.com/products/4120.html...

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Condensin Complex Product Focus Bethyl Laboratories
MCPH1 · A300-368A · PARP1 · A301-375A · A301-376A · IHC-00279 · SMC2 · A300-056A · A300-057A · A300-058A · A300-058A · SMC4 · A300-063A · A300-064A ...
http://www.bethyl.com/content/CONDENSIN_FOCUS...

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Maintenance of Genome Stability Conference 2008 | Abcam
7 Mar 2008 ... Kaiyi Li, Defective DNA damage responses and tumorigenesis in mice lacking Brit1 /MCPH1. Keynote 13: Andre Nussenzweig, Maintaining genomic ...
http://www.abcam.com/index.html?pageconfig=resource&rid=1084...

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Microcephalin Antibody / Microcephalin Antibodies
Microcephalin Antibody / Microcephalin Antibodies.
http://www.scbt.com/ko/table-microcephalin.html...

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