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jeb
| Symbol: | jeb | | Name(s): | jelly belly | | Type: | protein-coding | | Organism: | Drosophila melanogaster | | Synonyms: | CG13180, CG13182, CG30040, l(2)SH0422, l(2)k05644 | | Links: |
Pubmed,
Entrez Gene,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17285636 |
The ligand Jelly Belly (Jeb) activates the Drosophila Alk receptor tyrosine kinase (RTK) to drive PC12 cell differentiation, but is unable to activate the mouse ALK RTK. |
| 14523446 |
localized Jeb activates Alk and the downstream Ras/mitogen-activated protein kinase cascade to specify a select group of visceral muscle precursors as muscle-patterning pioneers |
| 14523447 |
Alk is the receptor for Jeb in the developing visceral mesoderm, and Jeb binding stimulates an Alk-driven, extracellular signal-regulated kinase-mediated signalling pathway, resulting in the expression of duf needed for muscle fusion |
| 17350579 |
these findings suggest that Jeb/Alk signaling helps R-cell axons to shape their environment for target recognition. |
jeb results (if any) from reagent suppliers | 
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