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ITGA2


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Symbol:ITGA2
Name(s):integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
Type:protein-coding
Organism:Homo sapiens
Synonyms:BR, CD49B, GPIa, VLA-2, VLAA2
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18231737 Observational study of gene-disease association. (HuGE Navigator)
17534386 genetic variability within ITGA2 may confer risk for ischemic stroke independent of conventional risk factors.
17127487 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17157856 Observational study of gene-disease association. (HuGE Navigator)
17160992 Observational study of genotype prevalence. (HuGE Navigator)
17164499 Observational study of gene-disease association. (HuGE Navigator)
17184645 Clinical trial of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17196570 Observational study of gene-disease association. (HuGE Navigator)
17264949 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17346829 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDancient ubiquitous protein 1 isoform 1integrin alpha 2 precursor--Pubmed
HPRDancient ubiquitous protein 1 isoform 1integrin alpha 2 precursor--Pubmed
HPRDalpha 1 type I collagen preproproteinintegrin alpha 2 precursor--Pubmed
HPRDalpha 1 type I collagen preproproteinintegrin alpha 2 precursor--Pubmed
HPRDalpha 2 type I collagenintegrin alpha 2 precursor--Pubmed
HPRDalpha 2 type I collagenintegrin alpha 2 precursor--Pubmed
HPRDCollagen type VIII alpha 1integrin alpha 2 precursor--Pubmed
HPRDalpha 1 type VIII collagen precursorIntegrin alpha 2--Pubmed
HPRDIntegrin alpha 2laminin, alpha 1 precursor--Pubmed
HPRDintegrin alpha 2 precursorLaminin, alpha 1--Pubmed

Recent Publications on ITGA2:

Pubmed Logo
A systematic meta-analysis of genetic association studies for diabetic retinopathy.
OBJECTIVE: Diabetic retinopathy is a sight-threatening microvascular...
1st October, 2009
Department of Ophthalmology, Flinders Medical Centre and Flinders Diabetes. 2009 Sep;58(9):2137-47. Epub 2009 Jul 8.
DOI Direct Link
Tubulointerstitial Nephritis Antigen-Like 1 Is Expressed in the Uterus and Binds with Integrins in Decidualized Endometrium During Postimplantation in Mice.
Extracellular matrix substrates contribute to both uterine and blastocyst...
25th September, 2009
Biol Reprod. 2009 Sep 23.
DOI Direct Link
Genetics of Platelet Reactivity in Normal, Healthy Individuals.
Summary Background: The Platelet Function Analyzer-100 (PFA-100) is widely...
11th September, 2009
Department of Molecular and Experimental Medicine, The Scripps Research J Thromb Haemost. 2009 Sep 9.
DOI Direct Link
Genotype-phenotype relationship for six common polymorphisms in genes affecting platelet function from 286 healthy subjects and 160 patients with mucocutaneous bleeding of unknown cause.
Polymorphisms affecting platelet receptors and intracellular proteins have...
11th September, 2009
University of Murcia, Centro Regional de Hemodonacion, Murcia, Spain. Br J Haematol. 2009 Jun;146(1):95-103. Epub 2009 Apr 21.
DOI Direct Link
[Association of the integrin gene polymorphisms with ischemic stroke and plasma lipid levels]
OBJECTIVE: To study the association of integrin alpha-2 (ITGA2) gene...
29th July, 2009
The Affiliated Hospital of Youjiang Medical College for Nationalities, Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2009 Apr;26(2):211-5.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7612181 Dual variable domain immunoglobulin and uses thereof
6994848 Lactobacillus paracasei strain GM-080 for treating allergy related diseases
6905827 Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
6818401 Method of detection and interpretation of mutations through expression or function tests of haploid genes
6673908 Tumor necrosis factor receptor 2

View more patents.

ITGA2 results (if any) from reagent suppliers

Google CSE Logo
Integrin α2 (C-9) Antibody sc-74466
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, ITGA2, 3673, 5q11.2, NM_002203 ...
http://www.scbt.com/datasheet-74466-integrin-alpha2-c-9-anti...

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Abgent - Cell and Structure Antibodies - Cell_structure
AT2563a, ITGA2 monoclonal antibody (M01), ELISA,IF,S-ELISA,WB-Ce,WB-Re, H. AT2564a, ITGA4 monoclonal antibody (M01), ELISA,S-ELISA,WB-Ce,WB-Re, H ...
http://www.abgent.com/products/category/cell_function/cell_s...

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Integrin α2 (DX5) Antibody sc-52591
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Mouse, Itga2, 16398, 13 D2.2, Q62469 ...
http://www.scbt.com/datasheet-52591-integrin-alpha2-dx5-anti...

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Protein and Antibody Solutions Provider - GenWay
ITGA2; BR; GPIa; CD49B; VLA-2; VLAA2 - Platelet membrane glycoprotein Ia; GPIa; Collagen receptor; VLA-2 alpha chain; CD49b antigen; Integrin alpha 2 ...
https://www.genwaybio.com/advanced_search_result.php?so=c&ig...

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CD Marker Products - R&D Systems
CD49b, Integrin alpha 2, ITGA2, VLA-2 alpha, 3673, Clone HAS3. CD49c, Integrin alpha 3, ITGA3, 3675. CD49d, Integrin alpha 4, ITGA4, VLA-4, 3676 ...
http://www.rndsystems.com/cdmarker.aspx...

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Mouse CD & Other Cellular Antigens
CD49b, VLA-2, Integrin α2, Itga2, 165kD, IntgF, platelets, T subset, megakaryocytes, NK subset, adhesion, CD49b/CD29 binds collagen & laminin, HMa2
...
http://www.ebioscience.com/ebioscience/whatsnew/mousecdchart...

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www.ebioscience.com
Itga2 platelets, T subset, megakaryocytes,. NK cells adhesion, CD49b/CD29 binds collagen & laminin. HMa2. ● ● ●. ●. DX5. ●. ● ● ● ● ...
http://www.ebioscience.com/ebioscience/whatsnew/pdf/MouseCD_...

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