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ITGAV
| Symbol: | ITGAV | | Name(s): | integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | CD51, DKFZp686A08142, MSK8, VNRA | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17615072 |
The rs3738919-C allele of the ITGAV gene is associated with rheumatoid arthritis in the European Caucasian population, suggesting ITGAV as a new minor susceptibility gene for rheumatoid arthritis. |
| 18062611 |
Report observed that alphav-beta3 integrins and Focal Adhesion Protein-Tyrosine Kinases co-localize and that fibrillin filament attachment sites to endothelial cells merge with these molecules. |
| 17408468 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17615072 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18090124 |
Alpha v beta 5, alpha v beta 5 and their ligands Del-1 and L1 play an important role in the process of tumor cells moving from the original place. |
| 18084301 |
uPAR is required to activate alphavbeta3 integrin in podocytes, promoting cell motility and activation of the small GTPases Cdc42 and Rac1 |
| 18045938 |
the studies demonstrate that Vbeta3 is a cellular receptor mediating both the cell adhesion and entry of KSHV into target cells through binding the virion-associated gB(RGD). |
| 17879163 |
These findings provide evidence that mutations in fibronectin, induce anoikis in human squamous cell carcinoma cells by modulating integrin alpha v-mediated phosphorylation of FAK and ERK. |
| 17275949 |
Mn(2+) promoted convergent changes in integrin alphavbeta6 conformation and Fb structure through activation of ERK/MAPK and MMP-9 |
| 16818691 |
PET Molecular imaging of alpha(v)beta3 expression with [18F]Galacto-RGD in humans correlates with alpha(v)beta3 expression as determined by immunohistochemistry. | →View more information from publications. |
Recent Publications on ITGAV: |  |
The ITGAV rs3738919 variant and susceptibility to rheumatoid arthritis in four Caucasian sample sets.
ABSTRACT: INTRODUCTION: Angiogenesis is an important process in the... | 13th October, 2009
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| Arthritis Res Ther. 2009 Oct 9;11(5):R152.
DOI Direct Link |
Csf2 null mutation alters placental gene expression and trophoblast glycogen cell and giant cell abundance in mice.
Genetic deficiency in granulocyte-macrophage colony-stimulating factor... | 23rd September, 2009
| Research Centre for Reproductive Health, School of Paediatrics and
| Biol Reprod. 2009 Jul;81(1):207-21. Epub 2009 Feb 18.
DOI Direct Link |
Enhanced focal adhesion assembly reflects increased mechanosensation and mechanotransduction at maternal-conceptus interface and uterine wall during ovine pregnancy.
The integrity of the fetal-maternal interface is critical for proper fetal... | 16th June, 2009
| Department of Veterinary Integrative Biosciences, Texas A&M University,
| Reproduction. 2009 Mar;137(3):567-82. Epub 2008 Dec 5.
DOI Direct Link |
Integrin alpha V polymorphisms and haplotypes in a Korean population are associated with susceptibility to chronic hepatitis and hepatocellular carcinoma.
BACKGROUND/AIMS: Integrins are cell surface receptors for extracellular... | 2nd June, 2009
| Medical Genomics Laboratory, Graduate School of Life Science and
| Liver Int. 2009 Feb;29(2):187-95. Epub 2008 Aug 7.
DOI Direct Link |
Role of the alpha v-integrin subunit in cell proliferation, apoptosis and tumor metastasis of laryngeal and hypopharyngeal squamous cell carcinomas: a clinical and in vitro investigation.
The objective of this study was to investigate the role of alpha... | 6th May, 2009
| Department of Otolaryngology/Head and Neck Surgery, Second Affiliated
| Eur Arch Otorhinolaryngol. 2009 Jan;266(1):89-96. Epub 2008 Apr 22.
DOI Direct Link |
→View more research publications. |
ITGAV results (if any) from reagent suppliers | 
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Integrin αV (P2W7) Antibody sc-9969
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, ITGAV, 3685, 2q32.1, NM_002210 ...
http://www.scbt.com/datasheet-9969-integrin-alphav-p2w7-anti...
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Search Results
Anti-ITGAV antibody produced in rabbit (1). HPA004856, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous ...
http://www.sigmaaldrich.com/catalog/Lookup.do?D7=0&D10=Vitro...
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,OR(LOCATION:US,LOCATION:0))&N3=mode%2520matchpartialmax&N5=Product%2520Name%2520or%2520No.&N4=Vitronectin&N25=14574647&N1=S_ID&ST=RS&F=PR&LangOvrride=ja_JP) |
Integrin αV (H9.2B8) Antibody sc-19669
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Mouse, Itgav, 16410, 2 D, P43406 ...
http://www.scbt.com/datasheet-19669-integrin-alphav-h9-2b8-a...
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CYR61 protein, Protein CYR61 recombinant protein
In skin fibroblasts it binds ITGA6/ITGB1, in endothelial cells, binds ITGAV/ ITGB3 and in platelets, ITGA2B/ITGB3. Binds, in vitro, ITGAV/ITGB5. ...
http://www.genwaybio.com/product_info.php?products_id=5022...
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Human Soluble Receptor Non-Hematopoietic Panel Proteome Profiler Array
ITGAV. 3685. D13, D14. Jagged 1. JAG1, CD339. 182. D15, D16. JAM-B/VE-JAM. CD322 , JAM2. 58494. D17, D18. JAM-C. JAM3. 83700. D19, D20. LRP-6. ___. 4040 ...
http://www.rndsystems.com/pdf/ARY012.pdf...
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Mouse CD & Other Cellular Antigens
CD51, VitronectinR, Integrin αv, Itgav, 125, 24kD, IntgF, platelets, megakaryocytes, endoth, osteoblasts, melanoma, adhesion, CD51/CD61 binds
vitronectin, ...
http://www.ebioscience.com/ebioscience/whatsnew/mousecdchart...
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Integrin
EGFR · ITGA4 (CD49d), ITGAV (CD51), PDGFRA · ERBB2 · ITGA5 (CD49e), ITGAX (CD11c ), PDGFRB · EZR (Ezrin), ITGA6 (CD49f), ITGB1 (CD29), VEGFR ...
http://www.invitrogen.com/site/us/en/home/Products-and-Servi...
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