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ITGB3
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18056258 |
a structural change in the conformation of anti-GPIIIa49-66 antibody contributes to its binding to the beta3 integrin and subsequent antibody-induced platelet fragmentation and aggregate dissolution |
| 17912026 |
Truncated beta3 may act as an anti-integrin and play a crucial role in cell migration, which is an important process in tumor invasion and metastasis. |
| 18208809 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18214290 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18260892 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18343248 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17959856 |
Fourteen of the antibodies reacted with a 29-kDa GPIIIa fragment comprising only the GPIIIa hybrid and plextrin-semaphorin-integrin homology domains |
| 18162078 |
Real-time PCR showed that ETOH significantly altered the expression of genes involved in cell adhesion. There was an increase in the expression of alpha and beta Laminins 1, beta Integrins 3 and 5, Secreted phosphoprotein1 and Sarcoglycan epsilon. |
| 18062611 |
Report observed that alphav-beta3 integrins and Focal Adhesion Protein-Tyrosine Kinases co-localize and that fibrillin filament attachment sites to endothelial cells merge with these molecules. |
| 18041653 |
oxidant systems external to platelets did not activate GP IIb/IIIa receptors while increased intra-platelet iron was associated with appearance of cytosolic oxidizing species and with GP IIb/IIIa receptor activation | →View more information from publications. |
Recent Publications on ITGB3: |  |
The Leu33Pro polymorphism in the ITGB3 gene does not modify BRCA1/2-associated breast or ovarian cancer risks: results from a multicenter study among 15,542 BRCA1 and BRCA2 mutation carriers.
Integrins containing the beta(3) subunit are key players in tumor growth... | 31st October, 2009
| IHCC (International Hereditary Cancer Centre), Department of Genetics and
| Breast Cancer Res Treat. 2009 Oct 30.
DOI Direct Link |
Ticagrelor yields consistent dose-dependent inhibition of ADP-induced platelet aggregation in patients with atherosclerotic disease regardless of genotypic variations in P2RY12, P2RY1, and ITGB3.
The platelet P2Y(12) receptor is the target of clopidogrel therapy, which... | 29th October, 2009
| Cardiovascular Research Unit, University of Sheffield, Sheffield, UK.
| Platelets. 2009 Aug;20(5):341-8.
DOI Direct Link |
[Clinicomorphological characteristics of renal disorders in patients with genetic thrombophilia]
AIM: To characterize the course and clinicomorphological features of... | 6th October, 2009
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| Ter Arkh. 2009;81(8):30-6.
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Do studies in humans better depict Th17 cells?
CD4(+) T helper (Th) lymphocytes represent a heterogeneous population of... | 30th September, 2009
| Department of Internal Medicine, Center of Excellence for Research,
| Blood. 2009 Sep 10;114(11):2213-9. Epub 2009 Jun 3.
DOI Direct Link |
External validation suggests Integrin beta 3 as prognostic biomarker in serous ovarian adenocarcinomas.
BACKGROUND: The majority of women with ovarian cancer are diagnosed in... | 25th September, 2009
| Department of Oncology, Institute of clinical sciences, University of
| BMC Cancer. 2009 Sep 23;9:336.
DOI Direct Link |
→View more research publications. |
ITGB3 results (if any) from reagent suppliers | 
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ITGB3 antibody, CD61 Antibody, Hamster Monoclonal Antibody
Buy quality hamster ITGB3 antibody (interacts with target species: mouse reacts with: rat nb), anti-ITGB3, CD61 antibody, hamster monoclonal antibody, ...
http://www.genwaybio.com/product_info.php?products_id=74068...
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p-Integrin β3 (Tyr 747) Antibody sc-101707
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, ITGB3, 3690, 17q21.32, NM_000212 ...
http://www.scbt.com/datasheet-101707-p-integrin-beta3-tyr-74...
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INTEGRIN B3 antibody, Integrin -beta3 (Phospho-Tyr773) Antibody ...
Disease: Defects in ITGB3 are a cause of Glanzmann thrombasthenia (GT) [MIM: 273800]; also known as thrombasthenia of Glanzmann and Naegeli. ...
http://www.genwaybio.com/product_info.php?products_id=210224...
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Page 1 of 2 e-mail: info@rockland-inc.com Visit our website at ...
(1995) Localization of the human homolog of the yeast cell division control 27 gene (CDC27) proximal to ITGB3 on human chromosome 17q21.3. Somat. Cell Mol. ...
http://www.rockland-inc.com/objects/catalog/product/extras/1...
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CYR61 protein, Protein CYR61 recombinant protein
In skin fibroblasts it binds ITGA6/ITGB1, in endothelial cells, binds ITGAV/ ITGB3 and in platelets, ITGA2B/ITGB3. Binds, in vitro, ITGAV/ITGB5. ...
http://www.genwaybio.com/product_info.php?products_id=5022...
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A9041 Arg-Gly-Asp-Ser ≥95% (HPLC)
assay, ≥95% (HPLC). composition, Peptide content, ~70%. Gene Information, human ... ITGA2B(3674), ITGB3(3690). mouse ... Itgb3(16416). storage temp. −20°C ...
https://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=A90...
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Search Results
Stock# - 008819 Strain name - B6.129S2-Itgb3/JSemJ JAX® Mice Database Site Section: JAX® Mice and services · jaxmice.jax.org/strain/008819.html - ...
http://www.jax.org/search/Main.jsp?sg=4&qt=drs&page=2...
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