Recent Publications on : |  |
The Leu33Pro polymorphism in the ITGB3 gene does not modify BRCA1/2-associated breast or ovarian cancer risks: results from a multicenter study among 15,542 BRCA1 and BRCA2 mutation carriers.
Integrins containing the beta(3) subunit are key players in tumor growth...
Direct Link | 31st October, 2009
| IHCC (International Hereditary Cancer Centre), Department of Genetics and
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Ticagrelor yields consistent dose-dependent inhibition of ADP-induced platelet aggregation in patients with atherosclerotic disease regardless of genotypic variations in P2RY12, P2RY1, and ITGB3.
The platelet P2Y(12) receptor is the target of clopidogrel therapy, which...
Direct Link | 29th October, 2009
| Cardiovascular Research Unit, University of Sheffield, Sheffield, UK.
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| [Clinicomorphological characteristics of renal disorders in patients with genetic thrombophilia]
| 6th October, 2009
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Do studies in humans better depict Th17 cells?
CD4(+) T helper (Th) lymphocytes represent a heterogeneous population of...
Direct Link | 30th September, 2009
| Department of Internal Medicine, Center of Excellence for Research,
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External validation suggests Integrin beta 3 as prognostic biomarker in serous ovarian adenocarcinomas.
BACKGROUND: The majority of women with ovarian cancer are diagnosed in...
Direct Link | 25th September, 2009
| Department of Oncology, Institute of clinical sciences, University of
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Genetics of Platelet Reactivity in Normal, Healthy Individuals.
Summary Background: The Platelet Function Analyzer-100 (PFA-100) is widely...
Direct Link | 11th September, 2009
| Department of Molecular and Experimental Medicine, The Scripps Research
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Genotype-phenotype relationship for six common polymorphisms in genes affecting platelet function from 286 healthy subjects and 160 patients with mucocutaneous bleeding of unknown cause.
Polymorphisms affecting platelet receptors and intracellular proteins have...
Direct Link | 11th September, 2009
| University of Murcia, Centro Regional de Hemodonacion, Murcia, Spain.
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Influence of cyclooxygenase-1 genotype on ex vivo aspirin response in patients at risk for stroke.
BACKGROUND: We sought to determine whether cyclooxygenase-1 (PTGS1)...
Direct Link | 5th September, 2009
| Department of Pharmacy Practice, College of Pharmacy, University of
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Genetic testing in the diagnostic evaluation of inherited platelet disorders.
Inherited disorders of platelets give rise to rare bleeding syndromes...
Direct Link | 28th August, 2009
| Centre de Reference des Pathologies Plaquettaires, Plateforme
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Molecular defects in ITGA2B and ITGB3 genes in patients with Glanzmann's thrombasthenia.
Summary Background: Glanzmann's thrombasthenia (GT) is an autosomal...
Direct Link | 21st August, 2009
| Department of Haematology, All India Institute of Medical Sciences, New
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A field synopsis and meta-analysis of genetic association studies in peripheral arterial disease: The CUMAGAS-PAD database.
In an electronic search of the literature, the authors systematically...
Direct Link | 17th July, 2009
| Department of Biomathematics, University of Thessaly, Larissa, Greece.
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Association and gene-gene interaction of SLC6A4 and ITGB3 in autism.
Autism is a heritable neurodevelopmental disorder with substantial genetic...
Direct Link | 10th July, 2009
| Institute for Human Genomics, University of Miami, Miller School of
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Simultaneous genotyping of human platelet antigen-1 to 17w by polymerase chain reaction sequence-based typing.
BACKGROUND AND OBJECTIVES: Genotyping for human platelet antigen (HPA)...
Direct Link | 3rd July, 2009
| Blood Center of Zhejiang Province, Zhejiang, China.
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Overexpression of malignancy-associated laminins and laminin receptors by angiotropic human melanoma cells in a chick chorioallantoic membrane model.
Background: As distinct from intravascular/lymphatic dissemination,...
Direct Link | 28th May, 2009
| Department of Pathology, University of Miami Miller School of Medicine,
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| Platelet GP IIIA polymorphism HPA-1 (PLA1/2) is associated with hypertension as the primary cause for end-stage renal disease in hemodialysis patients from Greece.
| 6th May, 2009
| Renal Unit,
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