|
| |
Dcr-2
| Symbol: | Dcr-2 | | Name(s): | Dicer-2 | | Type: | protein-coding | | Organism: | Drosophila melanogaster | | Synonyms: | CG6493, DCR2, DICER, dicer2 | | Links: |
Pubmed,
Entrez Gene,
Map Viewer.
|
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17381278 |
Dicer-1 and Dicer-2 are required for short interfering RNA (siRNA)-directed mRNA cleavage by facilitating distinct steps in the assembly of the RNA-induced silencing complex (RISC). |
| 15066284 |
SiRNAs must first interact with Dcr-2 to reach the R3 "holo-RISC" complex. Dcr-2 assembles into RISC along with the siRNAs, indicating that its role extends beyond the initiation phase of RNAi. |
| 14512631 |
results indicate that R2D2 bridges the initiation and effector steps of the Drosophila RNAi pathway by facilitating small interfering RNA (siRNA) passage from Dicer to RNA-initiated silencing complex (RISC) |
| 16554838 |
Dcr-2 is a host susceptibility locus for virus infections. |
| 15066283 |
Dicer-2 is required for siRNA-directed mRNA cleavage, though its RNase III activity is not required. Dicer-2 facilitates distinct steps in the assembly of siRISC. |
Dcr-2 results (if any) from reagent suppliers | 
|
Search Bioportfolio and other Life Science Sites for Dcr-2,
or search for Dcr-2 on BioPortfolio's antibody search engine.
This page has been viewed 126 times
Recent Search Terms used to find this page: dcr2 gene drosophila | TNF Dicer | Drosophila Dcr2 | dicer 2 dicer 1 | Drosophila DCR2 antibody | Dicer 2 antibody | .
Resources from the NCBI used on this page, NCBI's standard disclaimer applies.
|
