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JAG2
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 16327884 |
Observational study of gene-disease association. (HuGE Navigator) |
| 16899352 |
Observational study of gene-disease association. (HuGE Navigator) |
| 15292061 |
JAG2 was found to be overexpressed in malignant plasma cells from MM patients; coculture assay demonstrated that JAG2 induced the secretion of IL-6, VEGF, and IGF-1 in stromal cells; JAG2 overexpression may be an early event in the pathogenesis of MM |
| 11700865 |
expression required for spermatogenesis in humans and rats |
Recent Publications on JAG2: |  |
The Notch ligands Jagged2, Delta1, and Delta4 induce differentiation and expansion of functional human NK cells from CD34(+) cord blood hematopoietic progenitor cells.
Notch receptor signaling is required for T cell development, but its role... | 3rd November, 2009
| Department of Pathology, Case Western Reserve University School of
| Biol Blood Marrow Transplant. 2009 Sep;15(9):1026-37.
DOI Direct Link |
Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation.
Hedgehog signaling is aberrantly activated in glioma, medulloblastoma,... | 29th October, 2009
| M & M Medical Bioinformatics, Hongo 113-0033, Japan.
| Curr Mol Med. 2009 Sep;9(7):873-86.
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Ligand-dependent Notch signaling is involved in tumor initiation and tumor maintenance in pancreatic cancer.
PURPOSE: Aberrant activation of the Notch signaling pathway is commonly... | 23rd October, 2009
| Department of Pathology, The Sol Goldman Pancreatic Cancer Research
| Clin Cancer Res. 2009 Apr 1;15(7):2291-301. Epub 2009 Mar 3.
DOI Direct Link |
Differential regulation of splenic CD8- dendritic cells and marginal zone B cells by Notch ligands.
The importance of Notch signaling to maintain CD8- dendritic cells (DCs)... | 8th October, 2009
| Department of Immunology, Juntendo University School of Medicine, 2-1-1
| Int Immunol. 2009 Mar;21(3):295-301. Epub 2009 Jan 30.
DOI Direct Link |
Integration of IRF6 and Jagged2 signalling is essential for controlling palatal adhesion and fusion competence.
In mammals, adhesion and fusion of the palatal shelves are essential... | 15th September, 2009
| Faculty of Life Sciences, University of Manchester, Oxford Road,
| Hum Mol Genet. 2009 Jul 15;18(14):2632-42. Epub 2009 May 13.
DOI Direct Link |
→View more research publications. |
JAG2 results (if any) from reagent suppliers | 
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Jagged2 (H-143) Antibody sc-5604
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, JAG2, 3714, 14q32.33, NM_002226, ...
http://www.scbt.com/datasheet-5604-jagged2-h-143-antibody.ht...
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PE Anti-mouse Jagged 2 Antibody Anti-Jagged - BioLegend
Other Names: HJ2, Jagged2, Jagged-2 precursor, JAG2. Structure: A single pass transmembrane protein consisting of a large extracellular N-terminal which ...
http://www.biolegend.com/pe-anti-mouse-jagged-2-antibody-532...
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p51A antibody (ab2506) | Abcam
Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and ...
http://www.abcam.com/p51A-antibody-ab2506.html...
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Cell Surface Molecules / GPCRs
Jagged 2 (JAG2) polyclonal antibody, PAB-10532, $175.00. Junction cell adhesion molecule 2 (Jcam2) polyclonal antibody, PAB-10226, $190.00 ...
http://www.orbigen.com/dictionary/cat1089.htm...
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The goal of cell regulation is to deliver the proper quantity of ...
JAG2. AP6213a. MMP8. AP6232a. PSEN2. AM1100a. VEGF3. AP2511d. EZH1. AP1571a. KChIP1. AP6214a. MMP9. AP6304a. PSN1. AM1101a. VEGF4. AP2512a. EZH2. AP1573c ...
http://www.abgent.com/downloads/Cellular_Function_Diseases.p...
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Signaling Pathways: Notch Signaling
In mammals, members of the Delta-like (DLL1, DLL3, DLL4) and the Jagged (JAG1, JAG2) families, which are located in the signal-sending cell, ...
http://www.cellsignal.com/reference/pathway/Notch.html...
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