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JAK2
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18055983 |
Eight mutation-positive cases were identified, including one with a previously undescribed mutant JAK2 exon 12 allele and another with biallelic involvement. |
| 18056003 |
JAK2 exon 12 mutations were detected in 4 out of 20 polycythemia vera and idiopathic erythrocytosis V617F-negative patients and were only present in the myeloid lineage |
| 18230964 |
observations suggest that the clinical phenotype of the JAK2 exon 12 mutation is partly different from that of the JAK2 V617F mutation |
| 18092959 |
Higher haemoglobin and lower platelet levels in the JAK2 V617F mutation positive essential thrombocythemia patients. |
| 18216871 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18239666 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18270328 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18294066 |
Observational study of genetic testing. (HuGE Navigator) |
| 18297539 |
Observational study of genotype prevalence. (HuGE Navigator) |
| 18306358 |
Observational study of genotype prevalence. (HuGE Navigator) | →View more information from publications. |
Recent Publications on JAK2: |  |
Correlation of JAK2 V617F mutant allele quantitation with clinical presentation and type of chronic myeloproliferative neoplasm.
Activating JAK2 V617F mutation is present in many patients with chronic... | 3rd November, 2009
| Clinical Pathology Department, William Beaumont Hospital, Royal Oak,
| Ann Clin Lab Sci. 2009 Fall;39(4):345-50.
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Hormonal control of luminescence from lantern shark (Etmopterus spinax) photophores.
The velvet belly lantern shark (Etmopterus spinax) emits a blue... | 3rd November, 2009
| Laboratory of Marine Biology, Catholic University of Louvain, B-1348
| J Exp Biol. 2009 Nov;212(Pt 22):3684-92.
DOI Direct Link |
JAK2 Gets Histone H3 Rolling.
Activation of JAK2 is implicated in normal hematopoiesis as well as... | 3rd November, 2009
| Department of Medicine, Brigham and Women's Hospital and Harvard Medical
| Cancer Cell. 2009 Nov 6;16(5):365-6.
DOI Direct Link |
JAK2 V617F Mutation Detection: Laboratory Comparison of Two Kits Using RFLP and qPCR.
Aim: The JAK2 V617F mutation has been implicated in a variety of diseases... | 3rd November, 2009
| 1 Department of Pathology & Laboratory Medicine, American University of
| Genet Test Mol Biomarkers. 2009 Oct 30.
DOI Direct Link |
Expression of estrogen receptor alpha increases leptin-induced STAT3 activity in breast cancer cells.
Adipositas correlates with an enhanced risk of developing malignant... | 31st October, 2009
| Junior Research Group, Paul-Ehrlich-Institute, Langen, Germany.
| Int J Cancer. 2009 Oct 28.
DOI Direct Link |
→View more research publications. |
Press Releases on JAK2:
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| YM BIOSCIENCES REPORTS CYT997 ORAL VASCULAR DISRUPTING AGENT RESULTS PRESENTED AT AACR-NCI-EORTC MEETING |
17th November, 2009 |
YM BioSciences Inc. |
MISSISSAUGA, ON, Nov. 17 /PRNewswire-FirstCall/ - YM BioSciences Inc. (NYSE Amex: YMI; TSX: YM), a life sciences product development company that identifies and advances a diverse portfolio of
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| TargeGen Announces Successful Completion of Clinical Trial of JAK2 Inhibitor TG101348 in Myelofibrosis Patients |
22nd October, 2009 |
TargeGen, Inc. |
SAN DIEGO, Oct. 22 /PRNewswire/ -- TargeGen, Inc. today announced that the Company has successfully completed a 59 patient, multicenter clinical trial of TG101348, an oral, potent,
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| New Chromosomal Abnormality Identified in Leukemia Associated with Down Syndrome |
18th October, 2009 |
St. Jude Children's Research Hospital |
Study led by St. Jude Children's Research Hospital investigators expands understanding of acute lymphoblastic leukemia in children with Down syndrome, fueling hope
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| Cephalon Provides Clinical Update on Lestaurtinib in Relapsed Acute Myelogenous Leukemia |
19th June, 2009 |
Cephalon, Inc. |
FRAZER, Pa., June 19 /PRNewswire-FirstCall/ -- Cephalon, Inc. (Nasdaq: CEPH) today announced results from a pivotal clinical trial of lestaurtinib (CEP-701) in patients
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| Biomedical Sciences Companies Expanding in Asia Invested More Than US$500 Million in Singapore |
18th May, 2009 |
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ATLANTA, May 18 /PRNewswire/ -- Global biomedical sciences companies invested more than US$500 million in
Singapore in the year 2008. This rides on Singapore's strong scientific
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JAK2 results (if any) from reagent suppliers | 
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