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JUN
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18065414 |
ER stress increases MTHFR expression and IRE1 and c-Jun mediate this activation |
| 18073204 |
Nef binding to the MHC-I cytoplasmic tail stabilizes the interaction of a tyrosine in the MHC-I cytoplasmic tail with the natural tyrosine binding pocket in AP-1 |
| 17920329 |
c-Jun may sense the strength of genotoxic stress through DNA-damage dependent phosphorylation of T95, which in turn augments c-Jun transactivation by JNKs. |
| 17495958 |
Coordinated down- and up-regulation of the various AP-1 subunits in the course of epidermal wound healing is important for its undisturbed progress, putatively by influencing inflammation and cell-cell communication. |
| 17639289 |
Ras/MAPK cascade acts as the upstream signaling for AP-1 activation and IL-8 expression in toxin A-stimulated intestinal epithelial cells. |
| 17703412 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18062835 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17845581 |
Transactivation by AP-1 increased luciferase expression 85-fold, in the absence of stimulation. Synergistic interactions were demonstrated between Ets1, GATA-3 and AP-1. |
| 17637753 |
The AP-1 factor regulates the expression of cyclin D and E2F (the latter in turn regulates E2F-downstream genes), leading to cell cycle progression and breast cancer cell proliferation. |
| 18032824 |
AP-1 and NF-kappaB transcription factors are activated and EGF-R is expressed in these cells and associated with COX-2 and VEGF production | →View more information from publications. |
Recent Publications on JUN: |  |
Suppressive effects of T-412, a flavone on interleukin-4 production in T cells.
Interleukin (IL)-4 has been suggested as a molecular therapeutic target to... | 3rd November, 2009
| Lab of Pathology, College of Oriental Medicine, Daejeon University,
| Biol Pharm Bull. 2009 Nov;32(11):1875-9.
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Inhibition of double-stranded RNA-induced inducible nitric oxide synthase expression by fraxinellone and sauchinone in murine microglia.
Fraxinellone and sauchinone, isolated from natural substance, are known to... | 3rd November, 2009
| Department of Pharmacology, Seoul National University College of Medicine,
| Biol Pharm Bull. 2009 Nov;32(11):1870-4.
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A peptide from a ras effector-domain blocks ras-dependent cardiac hypertrophy in myocytes.
PNC-2 is a peptide corresponding to an effector domain (residues 96-110)... | 3rd November, 2009
| Molecular Cardiology Program, NY Harbor VA Medical Center, Brooklyn, New
| Ann Clin Lab Sci. 2009 Fall;39(4):351-60.
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Interstitial flow induces MMP-1 expression and vascular SMC migration in collagen I gels via an ERK1/2-dependent and c-Jun-mediated mechanism.
The migration of vascular smooth muscle cells (SMC) and fibroblasts into... | 3rd November, 2009
| The City College of New York/CUNY.
| Am J Physiol Heart Circ Physiol. 2009 Oct 30.
DOI Direct Link |
The Bile Acid Sensor Farnesoid X Receptor Is a Modulator of Liver Immunity in a Rodent Model of Acute Hepatitis.
Immune-mediated liver diseases including autoimmune and viral hepatitis... | 3rd November, 2009
| *Dipartimento di Medicina Clinica e Sperimentale, University of Perugia,
| J Immunol. 2009 Oct 30.
DOI Direct Link |
→View more research publications. |
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